The Influence of Loneliness on Pain Outcomes for Adolescents: A Cross-Sectional Survey.

Background: Loneliness, the perception that one's social relationships do not meet the desire for social connection, is a risk factor for poor mental and physical health. Adolescents with chronic pain experience higher rates of peer loneliness which persists over time. Previous studies used a single loneliness measure, limiting our understanding of the nature of their loneliness.

Insights from using an outcomes measurement properties search filter and conducting citation searches to locate psychometric articles of tools used to measure context attributes.

Objectives: To describe our experience with using a methodological outcomes measurement search filter (precise and sensitive versions of a filter designed to locate articles that report on psychometric properties of measurement tools) and citation searches to locate psychometric articles for tools that can be used to measure context attributes. To compare the precise filter when used alone and with reference list checking to citation searching according to number of records found, precision, and sensitivity.

Results: Using the precise filter, we located 130 of 150 (86.

Be Sweet to Babies: evaluation of an instructional video on neonatal pain management by nurses.

Objective: To describe the profile of nurses who work in hospital units that care for newborns; to verify nurses' prior knowledge on breastfeeding, skin-to-skin care and sweet tasting solutions for neonatal procedural pain relief; and to evaluate nurses' perceptions on the feasibility, acceptability and usefulness of the Portuguese version of the "Be Sweet to Babies" video.

Method: A cross-sectional study conducted in four units of a university affiliated hospital in São Paulo. Forty-five (45) nurses who answered the questionnaire and watched the video were included.

Herpes simplex virus: isolation, cytopathological characterization and antiviral sensitivity.

Background: Herpes simplex virus (HSV) infection is an endemic disease and it is estimated that 6095% of the adult population are infected with symptoms that are usually self-limiting, though they can be serious, extensive and prolonged in immunocompromised individuals, highlighted by the emergence of drug-resistant strains. The study of the wild-type HSV strains based on the cytopathogenic features and its antiviral sensitivity are important in the establishment of an antivirogram for controlling the infection.

Objective: This study sought to isolate and examine the cytopathological characteristics of circulating strains of the Herpes simplex virus, from clinical specimens and their sensitivity to commercially available antiherpesvirus drugs, acyclovir, phosphonophormic acid and trifluridine.