Positron emission tomography probes for stem cell monitoring: a review.

Stem cells possess unique self-renewal and differentiation capacities, that are central to cell replacement and tissue regeneration. The therapeutic potential of stem cell applications has garnered increasing attention in recent years for a spectrum of human diseases, from ischemic disorders to oncological challenges. Despite their potential, a comprehensive understanding of the biological behavior, efficacy, and safety of these cells remains elusive, hindering their clinical adoption.

New diagnostic strategy for multiple myeloma: A review.

Multiple myeloma (MM) is the second most prevalent hematological malignancy and is distinguished by the aberrant proliferation of monoclonal plasma cells inside the bone marrow and production of M-protein. This condition frequently results in bone deterioration, acute kidney damage, anemia, and hypercalcemia. However, the clinical manifestations and accompanying symptoms of MM vary and may change as the condition evolves.

Development and external validation of a multiparametric MRI-based radiomics model for preoperative prediction of microsatellite instability status in rectal cancer: a retrospective multicenter study.

Objectives: To establish and validate a radiomics model based on multiparametric magnetic resonance imaging (MRI), and to predict microsatellite instability (MSI) status in rectal cancer patients.

Methods: A total of 199 patients with pathologically confirmed rectal cancer were included. The MSI status was confirmed by immunohistochemistry (IHC) staining.

Genome-wide identification and characterization of the gene family in Chinese cabbage ( L. ssp. ).

Ovate family proteins (OFPs) are a class of proteins with a conserved OVATE domain that contains approximately 70 amino acid residues. OFP proteins are plant-specific transcription factors that participate in regulating plant growth and development and are widely distributed in many plants. Little is known about OFPs in to date.

[Effects of soil water content on H2O and CO2 exchange in tomato leaves in different seasons].

With tomato variety "L402" as test crop, this paper studied its photosynthetic and transpiration characteristics in different seasons under different soil water contents. Three treatments were installed, i. e.

[Multicenter phase II study of modified FOLFIRI regimen in the advanced colorectal cancer patient refractory to fluoropyrimidine and oxaliplatin].

Objective: To evaluate the efficacy and safety of modified FOLFIRI regimen in advanced colorectal cancer (CRC) patients refractory to fluoropyrimidine and oxaliplatin.

Methods: The modified FOLFIRI regimen consisted of intravenous infusion of irinotecan 180 mg/m2 d1 + LV 200 mg/m2 dl + 5-Fu 400 mg/m2 bolus dl plus 46-hour intravenous infusion of 5-Fu 2.4 g/m2, every 2 weeks as one cycle.

[Cold tolerance and wintering cultivation effect of different Welsh onion varieties].

With Welsh onion Zhangqiu as the contrast, this paper measured the physiological indices including electrolyte leakage, malondialdehyde content, protective enzyme activity, chlorophyll content, photosynthetic rate and root vitality of two introduced Welsh onion varieties Chunwei and Changhao, and identified their cold tolerance and wintering cultivation effect. The results showed that during wintering cultivation, all test Welsh onion varieties suffered low temperature stress, which led the electrolyte leakage and malondialdehyde content arrived at the maximum, while the chlorophyll content and photosynthetic rate dropped to the bottom at 15 January. At this time, the function data of physiological indices were 0.

[Protective effect of amifostine on cisplatin-induced nephrotoxicity and its mechanism].

Objective: To investigate the sites and pattern of renal toxicity in rats treated with cisplatin and the protective effect of amifostine, and to understand whether Fas/FasL system is involved in cisplatin-induced nephrotoxicity.

Methods: Forty-eight Sprague-Dawley rats were randomly divided into 3 groups: control group (0.9% saline solution), cisplatin group (6 mg/kg) and amifostine group (cisplatin 6 mg/kg + amifostine 200 mg/kg).

[Phase II clinical trial on China manufactured recombinant human interleukin-11 derivative in the prevention and treatment of chemotherapy-induced thrombocytopenia].

Objective: This phase II clinical trial was designed to evaluate the efficacy and toxicity of recombinant human interleukin-11 (rhIL-11) derivative manufactured in China in the prevention and treatment of chemotherapy-induced thrombocytopenia in cancer patients.

Methods: A total of 100 cancer patients with chemotherapy-induced thrombocytopenia (< or = 75 x 10(9)/L) were studied by self-cross control. Ninty-one of them received 2 cycles of chemotherapy.

[Vinorelbine plus cisplatin in the treatment of advanced non-small cell lung cancer previously treated with taxane-based chemotherapy].

Objective: To evaluate the efficacy and toxicity of vinorelbine plus cisplatin in the treatment of advanced non-small cell lung cancer (NSCLC) previously treated with taxane-based chemotherapy.

Methods: Thirty patients (0 - 1 score ECOG performance status) with stage IIIB/IV NSCLC previously treated with taxane-based chemotherapy were eligible for the study. Fifteen patients received the regimen of vinorelbine plus cisplatin (NP), the others received mitomycin, vindesine plus cisplatin (MVP).

[Result of phase II clinical trial of herceptin in advanced Chinese breast cancer patients].

Objective: To observe the clinical efficacy and adverse effects of herceptin for advanced Chinese breast cancer patients.

Methods: Thirty-one pathologically proved advanced breast cancer women were treated by herceptin. In the first week, a loading dose 4 mg/kg was administered by intravenous infusion and from the second week, a routine dose of 2 mg/kg was given every week for at least 3 months.