New Directions to Approach Oxidative Stress Related to Physical Activity and Nutraceuticals in Normal Aging and Neurodegenerative Aging.

Oxidative stress (OS) plays, perhaps, the most important role in the advanced aging process, cognitive impairment and pathogenesis of neurodegenerative disorders. The process generates tissue damage via specific mechanisms on proteins, lipids and nucleic acids of the cells. An imbalance between the excessive production of oxygen- and nitrogen-reactive species and antioxidants leads to a progressive decline in physiological, biological and cognitive functions.

Tensiomyography and Statistical Analysis Based Muscle Change Detection in Multiple Sclerosis for Smart Healthcare.

The impact of demyelinization on muscle fiber changes and the type of changes in multiple sclerosis (MS) is very hard to estimate. One of the major problems of MS patients is muscle fatigue and decrease of muscle force in the range of 16-57%. The objective of this research work is to estimate various aspects of muscle changes at tibial muscle (mTA) level using a noninvasive method named as tensiomyography (TMG).

Balance Rehabilitation Approach by Bobath and Vojta Methods in Cerebral Palsy: A Pilot Study.

In cerebral palsy (CP) the basis for rehabilitation comes from neuroplasticity. One of the leading therapeutic approaches used in the management of CP is the NDT Bobath therapy and Vojta therapy consists in trying to program the ideal movement patterns for the age. The aim of our research was to analyze, from a functional point of view, the evolution of the biomechanical parameters characterizing the balance, in children with CP.

Physical Activity Design for Balance Rehabilitation in Children with Autism Spectrum Disorder.

One of the characteristics of autism spectrum disorder (ASD) subjects is postural control deficit, which is significant when somatosensory perception is affected. This study analyzed postural stability evolution after physical therapy exercises based on balance training. The study included 28 children with ASD (average age 8 years, average weight 32.

Monitoring the Role of Physical Activity in Children with Flat Feet by Assessing Subtalar Flexibility and Plantar Arch Index.

Unlabelled: Flat foot is a common pediatric foot deformity which involves subtalar flexibility; it can affect the plantar arch. This study analyzes the evolution of two parameters, i.e.

New Recovery Strategies in Motor and Cognitive Functions, before, during and after Home-Confinement COVID-19, for Healthy Adults and Patients with Neurodegenerative Diseases: Review.

Distancing and confinement at home during the Coronavirus Disease 2019 (COVID-19) outbreak has led to worsening of motor and cognitive functions, both for healthy adults and for patients with neurodegenerative diseases. The decrease in physical activity, the cessation of the intervention of the recovery and the social distance imposed by the lockdown, has had a negative impact on the physical and mental health, quality of life, daily activities, as well as on the behavioral attitudes of the diet. The purpose of this paper was to evaluate the impact of decreasing physical activity and the affected emotional status in healthy adults and patients with neurodegenerative diseases in conditions imposed by the stay at home mandate of COVID-19, along with new interventions, such as telemedicine and telerehabilitation.

Plantar Pressure and Contact Area Measurement of Foot Abnormalities in Stroke Rehabilitation.

Background: Evaluation of plantar pressure in stroke patients is a parameter that could be used for monitoring and comparing how the timing of starting a rehabilitation program effects patient improvement.

Methods: We performed the following clinical and functional evaluations: initial moment (T1), intermediate (T2), and final evaluation at one year (T3). At T1 we studied 100 stroke patients in two groups, A and B (each 50 patients).

Functional muscle balance assessment in multiple sclerosis.

Background: Chronic demyelinisation in multiple sclerosis (MS) involves changes in the muscle structure and development of motor disorders.

Objective: The aim of this research is to assess the muscle balance of thigh muscle in MS using a noninvasive method, to have information about the muscle status prior to the rehabilitation and to prevent muscle damage.

Methods: The studied group consisted of 20 patients: 9 men and 11 women, with a mean age of 42 years.

Morphofunctional changes in distribution of pressure center in multiple sclerosis.

Introduction: Gait evaluation and assessment of motor performance are of utmost importance in the clinical management of multiple sclerosis (MS). A new approach to the analysis of static and dynamic balance of MS patients is the use of complex biomechanical analysis that includes an analysis of the distribution of the center of pressure (DCP) and loading, measured by using the pressure and force platforms.

Patients And Methods: The study was conducted on a total of 18 patients with MS, with the mean age of 41.

Morphofunctional muscle changes influence on foot stability in multiple sclerosis during gait prediction: The rehabilitation potential.

Background: Multiple sclerosis patients may suffer muscle changes that involve gait disorders of the kinetic and kinematic parameters also their gait may be clinically symmetrical or asymmetrical.

Objective: The aim of this study is to analyze how the muscle change, could affect the biomechanical parameters of foot stability during the gait, by disturb the motor control.

Methods: The study group consisted of 13 patients diagnosed with multiple sclerosis, presenting clinically detectable abnormal gait.

Prediction of motor disorders in multiple sclerosis using muscle change structure assessment.

Introduction: The neuropathogenesis of multiple sclerosis (MS) lesions has been explained by several mechanisms, which emphasize the unpredictable nature of these lesions. The aim of this study is to present the neuromuscular changes in MS at the patients without gait or motor disorders using a noninvasive method named tensiomyography (TMG).

Patients And Methods: The studied group included a number of seven MS patients without clinically detected gait disorders, with mean age of 33.

Analysis of neuromuscular parameters in patients with multiple sclerosis and gait disorders.

Unlabelled: Gait is a motor activity that requires understanding the dynamics and functional anatomical elements that make possible its cyclical conduct. Patients with multiple sclerosis record impaired balance and gait due to the process of demyelination, disorders that can be estimated by quantifying neuromuscular and cortical parameters. The aim of this paper is to present both an analysis of these parameters in the thigh muscles and an evaluation of cortical parameters obtained by visual evoked potentials (VEP).

Analysis of foot and ankle disorders and prediction of gait in multiple sclerosis rehabilitation.

Background: Multiple sclerosis (MS) is a disease of the central nervous system probably based on the autoimmune mechanism against myelin and the action of lymphocyte T. In the last 50 years, more than 150 descriptive studies regarding MS have focused on the etiopathogeny, treatment, diagnosis and prevention of the progressive evolution of MS. Most recently, studies in the field of rehabilitation and diagnosis have tried to present the postural aspects of control/foot and ankle control and gait pattern in MS.

Complex assessment in progressive multiple sclerosis: a case report.

Unlabelled: The study presents the case of a patient with progressive multiple sclerosis in relapses (PPMS) and proposes a comprehensive neuromuscular and biomechanical evaluation in order to achieve a predictive picture of gait evolution and balance disorders with disease progression.

Patient And Methods: The evaluation included: clinical, functional and neuromuscular evaluation by tensiomyography (TMG) and biomechanics (by RSscan platform force). Elements evaluated included the calf muscle groups (tibialis anterior and gastrocnemius) and the following parameters were assessed from neuromuscular point of view: contraction time, sustain time, delay, relax time and displacement amplitude after electrical stimulation.

Tensiomyography method used for neuromuscular assessment of muscle training.

Background: Within the structure of the skeletal muscle, there are fascicles of muscular fibers that are made up of serially distributed contractile elements. These elements are controlled by the nervous system, control which results in obtaining the muscular strength required for movement and its control. This study presents the neuromuscular assessment using tensiomyography method (TMG).

Biomechanical disorders of foot in multiple sclerosis.

Multiple sclerosis (MS) has a multifactorial etiology located at the interaction point of environmental factors--nutritional, geographic, infectious, etc.--with genetic factors, which confers susceptibility to disease or alters its development. This research presents a case study focused on complex assessment of a patient using clinical and functional assessment, biomechanical gait evaluation using RSScan force plate.

Morphofunctional aspects of lower limb in multiple sclerosis.

Gait, as an expression of the locomotive system, needs a complex biomechanical analysis, which allows the description of multiple sclerosis (MS) specific patterns, MS patients having a polymorphism of motion patterns. The studied group consisted of 13 MS patients with gait disorders, average age of the group was of 36 years. The evaluation of the subjects comprises: clinical evaluation (anamnesis, neurological examination), paraclinical evaluation (MRI), functional evaluation, neuro-physiologic evaluation and biomechanical evaluation.

Neuromuscular assessment in the study of structural changes of striated muscle in multiple sclerosis.

Unlabelled: The aim of this research is to present the results of neuromuscular assessment using tensiomyography (TMG) in multiple sclerosis for prediction the muscle changes. This study consists of 20 patients, selected conform to certain criteria. Thus, according to diagnosis and MS level, the studied group was divided into two subgroups: subgroup A, consisting of 13 MS patients with clinically detectable gait disorders, and subgroup B, made up of seven MS patients without clinically detectable gait disorders.

The three-dimensional modeling of the complex virtual human elbow joint.

The paper presents the algorithm to obtain a 3D virtual human elbow joint using CT images. For that purpose, we used CAD parametric software, which allows defining models with a high level of difficulty including complex 3D shapes. The virtual biomechanical system of the human elbow containing bones, ligaments and muscles is studied using the finite elements method and will be prepared for kinematical and dynamical simulations.

Neuromuscular investigation in diabetic polyneuropathy.

The aim of this paper is to present to new method for assessment diabetic polyneuropathy, before the moment of first clinical sign. Our working presents the method of tensiomyography (TMG) for assess the muscle composition rapports with muscle fibers types I and II. This composition can help to have an image regards the neuromuscular potential of muscle during diabetic process.

New approaches to cancellous bone bio-modeling.

The purpose of our research is to develop a model of cancellous bone that would allow us to forecast the changes in this structure under various mechanical forces and to simulate the dynamics of the cancellous bone behavior under these circumstances. At the same time, the suggested model will allow the measurement of the tension/forces applied onto the bone structure, with the purpose of comparing these with the in vitro values, identification of the areas with increased trauma risk, and simulation of the behavior of cancellous substance under different mechanical stimuli, which affect the growth and aging of the bone, as well as to study the materials used in endoprostheses. Two groups of methods have been used for this purpose: micro-anatomical methods - for the visualization of bone structures, and bio-mathematical methods (finite element method) - for the modeling of these structures.

Morpho-physiological aspects of rapports between bone and marrow bone.

Border between bone and marrow bone has many problems regards differentiation, cells topography, dynamic process of osteoclasto-genesis. So, this study tries to present morphophysiological aspects of this border, using lots of bone fragments that include compact and spongious bone. We observed genesis process of trabecular bone near the chondroclast zone and the osteoblast between sinusoid capillars.