Publications by authors named "Lifeng Zhang"

Background: CareHPV is a highly promising screening HPV assay that functions as a simplified and rapid point-of-care test, making it particularly well-suited for low-resource areas. It exhibits high sensitivity for detecting cervical precancerous lesions in cross-sectional study design. However, there is still limited evidence on the long-term protection of careHPV testing in the practical setting.

View Article and Find Full Text PDF
Article Synopsis
  • * Physiochemical modifications, including treatment with hydrochloric acid and thermal processes, significantly improve CFA's adsorption capabilities, achieving up to 88% removal of organic carbon and demonstrating effective PFAS adsorption.
  • * CFA shows a unique adsorption behavior, particularly for longer-chain PFAS, with a cost-effective profile, suggesting it could be a viable alternative to traditional carbon-based methods for treating landfill leachate.
View Article and Find Full Text PDF
Article Synopsis
  • LncRNAs play an important role in bladder cancer (BLCA), with this study focusing on how ferroptosis-related lncRNAs (DEFRlncRNAs) impact tumor growth and patient outcomes.
  • Researchers identified an 18-lncRNA signature that predicts patient prognosis and showed that altering the expression of specific lncRNAs like AL355353.2 and AL136084.3 affects cancer cell death in lab experiments.
  • The study found that AL136084.3 interacts with the protein NUPR1, suggesting a potential link in regulating cancer progression and providing insight into possible therapeutic targets.
View Article and Find Full Text PDF

Bone defects have always been a difficult problem in clinical practice. Taxifolin (TAX) is beneficial to bone regeneration. In order to obtain more attractive biomaterials, we extracted cellulose (LC) from larch sawdust and prepared a TAX-loaded hydrogel (DCT) together with L-arginine chitosan (CA).

View Article and Find Full Text PDF

Objectives: Based on the Caregiving Stress Theory and Cognitive Theory of Stress and Coping, this study examined whether increase in caregiving stressors had an impact on subsequent increase in different forms of elder abuse. Additionally, this study evaluated how these relationships were influenced by caregiver (CG) coping strategies.

Method: A group of 800 Chinese primary family CGs and their care recipients (CRs) with mild cognitive impairment or mild-to-moderate dementia were analyzed.

View Article and Find Full Text PDF

A tandem mass tagging-labeled proteomic approach was employed to explore the relationship between quality parameters and protein changes in large yellow croaker fillets refrigerated under carbon dioxide, oxygen, and nitrogen atmospheres. After 96 h, fillets stored in carbon dioxide and nitrogen showed improved texture, water-holding capacity, and color, compared to those stored in oxygen. Functional analysis respectively identified 117 and 65 differentially expressed proteins in carbon dioxide and nitrogen, including key proteins such as troponin, myosin light chain, actin, and collagen types IV and XIII, that were linked to extracellular adhesion, cytoskeleton integrity, energy metabolism, and membrane functions.

View Article and Find Full Text PDF

Background: Robot-assisted surgery (RAS) is being performed with increasing frequency in pediatric oncology. We report our experience with RAS for renal tumors in children and compare the outcomes between RAS and laparoscopic surgery (LAS).

Methods: A total of 23 patients with renal tumor who underwent minimally invasive surgery (MIS) between January 2020 and December 2023 were included in the study.

View Article and Find Full Text PDF

Context-aware emotion recognition (CAER) leverages comprehensive scene information, including facial expressions, body postures, and contextual background. However, current studies predominantly rely on facial expressions, body postures, and global contextual features; the interaction between the agents (target individuals) and other objects in the scene is usually absent or incomplete. In this article, a three-dimensional view relationship-based CAER (TDRCer) method is proposed, which comprises two branches: the personal emotional branch (PEB) and the contextual emotional branch (CEB).

View Article and Find Full Text PDF
Article Synopsis
  • The detection of phosphate ions is important across various fields like chemistry, biology, medicine, environment, and industry, yet current methods, such as blue molybdenum colorimetry, have limitations in cost, complexity, and pre-treatment.
  • This study focuses on developing an electrochemical sensor using an iron metal electrode, which simplifies the detection process while maintaining high efficiency and precision.
  • Characterization of the sensor (Fe-PME) was conducted using cyclic voltammetry, scanning electron microscopy, and energy dispersive X-ray spectroscopy, showing that it effectively responds to varying concentrations of phosphate ions and performs better than traditional methods.
View Article and Find Full Text PDF

As a battery-type anode material for sodium ion capacitors (SICs), titanate (HTiO·HO, HTO) exhibits good rate capability due to its layered structure, easy to insert Na ions and low potential during sodium-ion storage. However, the structure is unstable due to the lattice distortion resulting from the irreversible embedment of Na in the process of sodium storage. So there is a significant mismatch between the dynamic reaction of the HTO anode and the capacitive cathode.

View Article and Find Full Text PDF

The phase with composition TiFeCO, tetra-titanium diiron carbide oxide, was unexpectedly synthesized by high-pressure sinter-ing (HPS) of a stoichiometric mixture with nominal composition TiFe. The TiFeCO phase crystallizes in the space group and can be considered as the TiFe structure filled with C and O atoms co-occupying the same octa-hedral void [occupancy ratio 0.82 (7):0.

View Article and Find Full Text PDF
Article Synopsis
  • The proposed co-freezing localized CRISPR-Cas12a (CL-Cas12a) strategy enhances nucleic acid detection for disease diagnosis, enabling rapid and sensitive testing.* -
  • CL-Cas12a can quantitatively detect nucleic acids as low as 98 aM in just 30 minutes and demonstrates high specificity.* -
  • The technique was successfully utilized to identify human papillomavirus infections and lung cancer mutations, showcasing its potential for effective diagnostic and monitoring applications.*
View Article and Find Full Text PDF

The lithium lanthanum titanium oxide (LLTO) perovskite is one type of superior lithium (Li)-ion conductor that is of great interest as a solid-state electrolyte for all-solid-state lithium batteries. Structural defects and impurity phases formed during the synthesis of LLTO largely affect its Li-ion conductivity, yet the underlying Li diffusion mechanism at the atomic scale is still under scrutiny. Herein, we use aberration-corrected transmission electron microscopy to perform a thorough structural characterization of the LLTO ceramic pellet.

View Article and Find Full Text PDF

With the development of automation and intelligent technologies, the demand for autonomous mobile robots in the industry has surged to alleviate labor-intensive tasks and mitigate labor shortages. However, conventional industrial mobile robots' route-tracking algorithms typically rely on passive markers, leading to issues such as inflexibility in changing routes and high deployment costs. To address these challenges, this study proposes a novel approach utilizing active landmarks-battery-powered luminous landmarks that enable robots to recognize and adapt to flexible navigation requirements.

View Article and Find Full Text PDF

Sulfation of polysaccharides can affect their biological activity by introducing sulfate groups. Skin burns occur regularly and have a great impact on normal survival. In this study, sulfated arabinogalactan (SAG) was prepared by sulfation, and polyvinyl alcohol (PVA) was used to prepare hydrogels for the treatment of scalded skin in mouse.

View Article and Find Full Text PDF
Article Synopsis
  • - This study utilized advanced synchrotron-based X-ray imaging to explore the drying process of individual pharmaceutical granules during tablet manufacturing, overcoming challenges in quantifying internal changes through traditional methods.
  • - Two excipients, lactose monohydrate and microcrystalline cellulose, were tested both alone and in combination with active ingredients acetaminophen and carbamazepine, focusing on how moisture content affected drying properties.
  • - Findings indicated that drying time and composition significantly affect pore volume and moisture removal, while active ingredient nature (hydrophilicity vs. hydrophobicity) plays a crucial role in the drying behavior of certain mixtures, particularly influencing acetaminophen more than carbamazepine.
View Article and Find Full Text PDF

Bone defects caused by trauma, infection and congenital diseases still face great challenges. Dihydromyricetin (DHM) is a kind of flavone extracted from Ampelopsis grossedentata, a traditional Chinese medicine. DHM can enhance the osteogenic differentiation of human bone marrow mesenchymal stem cells with the potential to promote bone regeneration.

View Article and Find Full Text PDF

Chemical crosslinking is a method widely used to enhance the mechanical strength of biopolymer-based scaffolds. Polysaccharides are natural and biodegradable carbohydrate polymers that can act as crosslinking agents to promote the formation of scaffolds. Compared to synthetic crosslinking agents, Polysaccharide-based crosslinking agents have better biocompatibility for cell adhesion and growth.

View Article and Find Full Text PDF
Article Synopsis
  • * The researchers developed a new method called localized Cas12a-based cascade amplification (LCas12a-CA), which uses gold nanoparticles to enhance the stability and speed of the detection process.
  • * This method allows for extremely sensitive detection of APE1, with a detection limit over 60 times lower than previous methods, making it a promising tool for cancer diagnosis and prognosis.
View Article and Find Full Text PDF

We present a study of high-performance electrochemical phosphate sensors, which are exquisitely designed and easy to operate. We innovatively utilized the insolubility of nickel phosphate and developed a new type of sensor through electrochemical methods. The experiment first used cyclic voltammetry to determine -0.

View Article and Find Full Text PDF

Objective: This study aimed to investigate the safety and efficacy of a new Chinese device using microwave ablation for treating symptomatic great saphenous vein (GSV) varicose veins (VVs).

Methods: This prospective, single-arm, single-center, cohort study investigated the safety and efficacy of endovenous microwave ablation for the treatment of symptomatic VVs. A total of 50 patients with lower limb varicose veins were enrolled from the Hospital of Chengdu University of Traditional Chinese Medicine.

View Article and Find Full Text PDF
Article Synopsis
  • - The study examines the long-term progression and treatment outcomes of dystrophinopathy in China, focusing on data from 2097 patients over a decade to provide a clearer understanding of the condition's natural course. - The research identifies various genetic variants related to dystrophinopathy, with most patients diagnosed with Duchenne muscular dystrophy (DMD) and a significant percentage confirmed to have received glucocorticoid treatment, which showed benefits like delayed loss of ambulation. - Key findings also highlight the use of cardiac medications among affected patients and the necessity for ventilator support in some cases, emphasizing the need for improved clinical management and treatment strategies for dystrophinopathy in the region.
View Article and Find Full Text PDF

Background: Currently, the treatment outcomes for complex congenital arteriovenous malformations (AVMs) remain unsatisfactory. This article reports on the utilization of an abdominal aortic stent graft, in conjunction with embolization techniques, for managing acute heart failure triggered by complex congenital arteriovenous malformations in the lower limb.

Case Presentation: We present a case involving a patient with congenital AVMs in the lower limb, who had suffered from prolonged swelling in the left lower limb and recently developed symptoms of heart failure.

View Article and Find Full Text PDF