Bifunctional CoFe/HZSM-5 catalysts orient CO hydrogenation towards liquid hydrocarbons.

Converting CO to liquid (C) hydrocarbons remains a significant hurdle. Our study shows that CoFe/HZSM-5 boosts C selectivity to 73.4%, up from 59% for Fe/HZSM-5.

A Reversible Fluorescent Probe for In Situ Monitoring Redox Imbalance during Mitophagy.

Mitophagy is the lysosome-dependent degradation of damaged and dysfunctional mitochondria, which is closely associated with HO-related redox imbalance and pathological processes. However, development of fast-responding and highly sensitive reversible fluorescent probes for monitoring of mitochondrial HO dynamics is still lacking. Herein, we report a reversible fluorescent probe () that enables real-time imaging of HO-related redox imbalance.

Brain-targeted Near-Infrared Nanobeacon for In Situ Monitoring HS Fluctuation during Epileptic Seizures.

Epilepsy is a neurological brain disease, and its recurrent seizures are related to the reductive substance-powered antioxidant defense system (ADS). However, until now, there has been no report on the study of in situ antioxidant fluctuation during epilepsy of varying severity. In this work, hydrogen sulfide (HS) was selected as the model target, a HS-responsive near-infrared fluorophore was designed and synthesized, and an amphiphilic molecule was synthesized and modified with angiopep-2 peptide at its hydrophilic terminus.

Extracting Effective Image Attributes with Refined Universal Detection.

Recently, image attributes containing high-level semantic information have been widely used in computer vision tasks, including visual recognition and image captioning. Existing attribute extraction methods map visual concepts to the probabilities of frequently-used words by directly using Convolutional Neural Networks (CNNs). Typically, two main problems exist in those methods.

Oxidase-mimicking activity of perovskite LaMnO nanofibers and their application for colorimetric sensing.

Nanomaterials with ABX-type perovskite structure have attracted considerable and increasing attention due to their unique physical and chemical properties as well as promising applications in various fields. In this work, we have developed a simple electrospinning followed by a calcination process to prepare ABO-type perovskite LaMnO nanofibers as efficient oxidase mimics for the detection of l-cysteine. The oxidase-like catalytic activity of the prepared LaMnO nanofibers is heavily dependent on the calcination temperature which results in different sizes of the LaMnO crystals and their crystallinity, and the maximum activity is achieved at the calcination temperature of 700 °C.

Five-year antibody persistence in children after one dose of inactivated or live attenuated hepatitis A vaccine.

In China, both inactivated hepatitis A (HA) vaccine and live attenuated HA vaccine are available. We conducted a trial to evaluate 5-year immune persistence induced by one dose of inactivated or live attenuated HA vaccines in children. Subjects with no HA vaccination history had randomly received one dose of inactivated or live attenuated HA vaccine at 18-60 months of age.

The Uncommon Channel-Based Ln-MOFs for Highly Selective Fe Detection and Superior Rhodamine B Adsorption.

Two new isostructural 3D lanthanide-organic frameworks [H N(Me) ] [Ln (OH)(bpt) (H O) ] (DMF) ⋅(H O) (1-Ln; Ln=Sm and Eu) with a 1D channel (25 Å) have been successfully assembled from the rare trinuclear [Ln (OH)(COO) ] clusters and biphenyl-3,4',5-tricarboxylic acid (H bpt) and exhibit high stability towards water in the pH range 3-10. MOF 1-Eu is a promising luminescent probe for sensing Fe in aqueous solution and is also selective towards rhodamine B (RhB) with a superior adsorption capacity of 735 mg g , which is the highest among the reported Ln-MOFs for RhB removal so far. Periodic DFT calculations further confirmed the selective adsorption of rhodamine B over other dyes.

Manipulation the behavior of supramolecular hydrogels of α-cyclodextrin/star-like block copolymer/carbon-based nanomaterials.

A new supramolecular hydrogel self-assembled between α-cyclodextrin (α-CD) and a star-like block copolymer AE73 was prepared. The cooperation effect of complexation of poly-(ethylene oxide) (PEO) segments with α-CD and the hydrophobic interaction between poly-(propylene oxide) (PPO) blocks resulted in the formation of the supramolecular hydrogel with a strong macromolecular network. Then two kinds of carbon materials (graphene and graphene oxide) were successfully incorporated into the above α-CD/AE73 hydrogel to further enhance the mechanical properties.

Efficacy, safety, and immunogenicity of an enterovirus 71 vaccine in China.

Background: Enterovirus 71 (EV71) is one of the major causative agents of outbreaks of hand, foot, and mouth disease or herpangina worldwide. This phase 3 trial was designed to evaluate the efficacy, safety, and immunogenicity of an EV71 vaccine.

Methods: We conducted a randomized, double-blind, placebo-controlled, multicenter trial in which 10,007 healthy infants and young children (6 to 35 months of age) were randomly assigned in a 1:1 ratio to receive two intramuscular doses of either EV71 vaccine or placebo, 28 days apart.

Immunogenicity, safety, and immune persistence of a novel inactivated human enterovirus 71 vaccine: a phase II, Randomized, double-blind, placebo-controlled Trial.

Background: Vaccination is considered a top priority for the control of human enterovirus 71 (EV71) infection outbreaks.

Methods: On the basis of phase I trial results, we conducted a double-blind, randomized, controlled trial to evaluate the optimal dose, immunogenicity, safety and immune persistence of the vaccine. A total of 480 healthy infants were randomly assigned to receive 2 injections of 100 U of vaccine, 200 U of vaccine, 400 U of vaccine, or placebo.

Optimal vaccination strategies for 2009 pandemic H1N1 and seasonal influenza vaccines in humans.

A randomized clinical trial was conducted to assess whether the immunogenicity of seasonal and pandemic (H1N1/09) influenza vaccines is affected by the order of vaccine administration. 151 healthy adult volunteers were randomized into three groups. All groups received one dose (15 μg haemagglutinin) each of a pandemic H1N1 vaccine and a seasonal trivalent vaccine.

A rapid immune response to 2009 influenza A(H1N1) vaccines in adults: a randomized, double-blind, controlled trial.

A double-blind, randomized, controlled trial involving 706 adults was conducted to evaluate the immunogenicity and safety of different dosages of whole-virion or split-virion H1N1 influenza vaccines with or without aluminum adjuvant. A rapid and strong immune response was induced at day 14 after the first injection. The seroprotection rates ranged from 72.

Preparation and characterization of SARS in-house reference antiserum.

A reference antiserum for SARS is in urgent need in the development of SARS vaccine and other serological test of SARS research. Convalescent serum was collected from clinical confirmed patient. ELISA, Western-blotting and neutralization assay detected specific antibody against SARS coronavirus.

[Observation and comparison of the flowers of Pogostemon cablin from different habitats].

The present work is concerned in the observation and comparison among the flowers of Pogostemon cablin (Blanco) Benth. from 3 different habitats by microscopical identification and electron microscopy scanning. The results provided scientific basis for recognition and distinction of Pogostemon cablin varieties.