Publications by authors named "Liesl Schroedl"

Article Synopsis
  • Dermatologic patient education materials often exceed a seventh- to eighth-grade reading level, prompting the study to evaluate large language models (LLMs) like ChatGPT and DermGPT for generating simpler content.
  • The study focuses on generating patient education materials for both common and rare skin conditions at specified fifth- and seventh-grade reading levels while maintaining the original message.
  • Results indicated that current materials have a higher average reading level (around 9.35 for common and 9.50 for rare conditions), and while LLMs produced PEMs at lower reading levels, consistency in meaning varied, with GPT-4 showing a stronger performance for fifth-grade content.
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Article Synopsis
  • * It has been linked to the development of certain secondary tumors, primarily from follicular germ cells.
  • * The authors present three cases where individuals had both a melanocytic nevus and nevus sebaceus to illustrate this uncommon occurrence.
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Objective: The purpose of this meta-analysis was to determine whether perioperative fascia iliaca compartment blockade (FICB) decreases mortality in patients with hip fracture.

Methods: MEDLINE (PubMed and Ovid platforms), Web of Science, EMBASE, and Cochrane Database of Systemic Reviews were screened for "fascia iliaca compartment block, hip fracture" articles in English, in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, from January 1, 2005, to March 1, 2020. All relevant randomized controlled trials and cohort and case-control studies were included for analysis.

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The COVID-19 pandemic stimulated adoption of teledermatology via video and telephone modalities by outpatient dermatology clinics. However, it was unknown how patient-related factors may have impacted, whether video or phone visits were used, and if visit modality impacted management. Consequently, we conducted a retrospective cross-sectional study of teledermatology visits occurring between March 30, 2020 and May 30, 2020 at an urban tertiary care center.

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Cidofovir is a broad-spectrum antiviral agent that has shown efficacy against skin lesions caused by human papillomavirus (HPV). We present a case of extensive verruca vulgaris lesions refractory to imiquimod that was responsive to topical cidofovir therapy, and analyze other case series in the literature of successful treatment of benign HPV-associated skin lesions with topical cidofovir. Topical cidofovir's favorable response rate and tolerability make it a useful treatment option for patients of differing ages and immune status who have nonmalignant HPV-associated skin lesions and desire topical therapy.

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Background/objectives: The COVID-19 pandemic necessitated rapid implementation of telemedicine at medical centers across the United States. As telemedicine is expected to persist beyond the pandemic in subspecialties like pediatric dermatology, there is growing concern that socioeconomic factors may contribute to inequitable telemedicine access. This study aims to identify factors associated with disparities in telemedicine use among pediatric dermatology patients during the pandemic.

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Obesity affects nearly one billion globally and can lead to life-threatening sequelae. Consequently, there is an urgent need for novel therapeutics. We have previously shown that laminin, alpha 4 () knockout in mice leads to resistance to adipose tissue accumulation; however, the relationship between and obesity in humans has not been established.

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Laminins are extracellular matrix proteins that reside in the basement membrane and provide structural support in addition to promoting cellular adhesion and migration. Through interactions with cell surface receptors, laminins stimulate intracellular signaling cascades which direct specific survival and differentiation outcomes. In metabolic tissues such as the pancreas, adipose, muscle, and liver, laminin isoforms are expressed in discrete temporal and spatial patterns suggesting that certain isoforms may support the development and function of particular metabolic cell types.

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