Publications by authors named "Liesbeth de Vries"
This article describes the translation and cultural adaptation process of the WRITIC (Writing Readiness Inventory Tool in Context) into European Portuguese. We examined the content and convergent validity, test-retest, and interrater reliability on the norm-referenced subdomain of the Portuguese (PT) WRITIC Task Performance (TP). To establish content validity, we consulted six experts in handwriting.
View Article and Find Full Text PDFIntroduction: Early evaluation of writing readiness is essential to predict and prevent handwriting difficulties and its negative influences on school occupations. An occupation-based measurement for kindergarten children has been previously developed: Writing Readiness Inventory Tool In Context (WRITIC). In addition, to assess fine motor coordination two tests are frequently used in children with handwriting difficulties: the modified Timed Test of In-Hand Manipulation (Timed TIHM) and the Nine-Hole Peg Test (9-HPT).
View Article and Find Full Text PDFFluorescent labels are well suited as tracers for cancer drug monitoring. Identifying cellular target regions of these drugs with a high resolution is important to assess the working principle of a drug. We investigate the applications of label-free nonresonant four-wave mixing (NR-FWM) microscopy in biological imaging in combination with fluorescence imaging of fluorescently labeled cancer drugs.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to assess and compare the effectiveness of the Nine-Hole Peg Test (9-HPT) and the Timed Test of In-Hand Manipulation (Timed-TIHM) in determining children's readiness to write, as measured by the Writing Readiness Inventory Tool In Context-Task Performance (WRITIC-TP).
- Results showed that both tests had similar correlations with handwriting readiness, but neither outperformed the other, indicating they assess different aspects of fine motor performance.
- The reliability of the Timed-TIHM was confirmed, but limitations included an uneven number of participants in subgroups, suggesting the need for further research on fine motor skills and handwriting proficiency across various age groups.
Article Synopsis
- The study evaluated how well a new kindergarten handwriting readiness assessment predicts handwriting performance in first grade.
- The assessment included the WRITIC, Beery-Buktenica VMI, and Nine-Hole Peg Test, which measure various skills needed for effective handwriting.
- Key findings showed that all three assessments, along with factors like sustained attention and gender, were significant predictors of handwriting success, with WRITIC being the strongest indicator for quality and Beery VMI and 9-HPT for speed.
Article Synopsis
- The Writing Readiness Inventory Tool in Context (WRITIC) measures writing readiness in Dutch kindergarten children aged 5 and 6, demonstrating strong content and construct validity.
- Expert evaluations (94.4% agreement) and factor analysis confirmed the tool's reliability and identified two main performance factors for paper-and-pencil tasks.
- Significant differences between good and poor performers in two subdomains, "Sustained attention" and "Task performance," suggest WRITIC is an effective tool for classroom use.
Purpose: Molecular optical imaging using monoclonal antibodies is slow with low tumour to background ratio. We used anti-HER2 VHHs conjugated to IRDye 800CW to investigate their potential as probes for rapid optical molecular imaging of HER2-positive tumours by the determination of tumour accumulation and tumour to background levels.
Methods: Three anti-HER2 VHHs (11A4, 18C3, 22G12) were selected with phage display and produced in Escherichia coli.