Publications by authors named "Liesbeth Vanheeswijck"
Background: Lysine methyltransferase 2A () rearrangements are commonly found in juvenile acute myeloid leukaemia (AML). Although distinct diseases, there is a known clinical overlap between -rearranged AML and juvenile myelomonocytic leukaemia (JMML). Both occur in infancy or early childhood and present with abnormal monocytosis.
View Article and Find Full Text PDFThe Challenges of Crizotinib Treatment in a Child With Anaplastic Large Cell Lymphoma.
J Pediatr Pharmacol Ther
August 2021
Survival in cases involving childhood malignancy is reaching nearly 80% in high-income countries, yet cancer remains one of the leading disease-related causes of death in children. In adult oncology the role of targeted therapies is established, but information regarding the use of these therapies in children is limited, largely because targeted therapies were developed in the context of adult pathologies. The few pediatric reports regarding crizotinib, an anaplastic lymphoma kinase (ALK) inhibitor, seem promising.
View Article and Find Full Text PDFArticle Synopsis
- Obesity can cause a sleep problem called obstructive sleep apnea (OSA) in kids, so it's important to check for it early.
- The study checked if using a device that measures oxygen levels at night (oximetry) could help screen for OSA in overweight kids, instead of the more complex sleep test (polysomnography).
- The results showed that oximetry wasn't very good on its own for finding OSA, so we need to look for better ways to test for it in the future.