In this paper, we report self-assembled sonogels formed from 1,4-naphthalenedicarbonyldinicotinic acid hydrazide (NDC-NN3) in some liquids including ethanol, tetrahydrofuran (THF), 1,4-dioxane, -propanol, -butanol and -pentanol. When the clear solution of NDC-NN3 in the selected liquids mentioned above at a suitable concentration was irradiated with ultrasound waves at room temperature, a sonogel was formed. Upon heating, the sonogel dissolved gradually and finally became a clear solution again.
View Article and Find Full Text PDFObjective: To evaluate the feasibility and efficacy in selected T4a glottic cancer (thyroid cartilage invasion adherence to the anterior commissure) treated with frontolateral vertical partial laryngectomy (FLVPL) and laryngeal framework reconstruction using titanium mesh.
Methods: Six patients with the limited T4a glottic cancer with thyroid cartilage destruction adherence to the anterior commissure, underwent FLVPL from 2009 to 2016 in Sun Yat-Sen University Cancer Center. All patients were followed up postoperatively.
As one of the most important and fruitful methods, supramolecular self-assembly has a significant advantage in designing and fabricating functional soft materials with various nanostructures. In this research, a low-molecular-weight gelator, ,'-di(pyridin-4-yl)-pyridine-3,5-dicarboxamide (PDA-N4), was synthesized and used to construct self-assembled gels a solvent-mediated strategy. It was found that PDA-N4 could form supramolecular gels in mixed solvents of water and DMSO (or DMF) at high water fraction (greater than or equal to 50%).
View Article and Find Full Text PDFHead and neck squamous cell carcinoma (HNSCC), which occurs frequently worldwide, is characterized by high risk of metastasis. MicroRNAs (miRNAs) play crucial roles in tumorigenesis and cancer development. In this study, miR-29c-5p was identified using three high throughput microarrays.
View Article and Find Full Text PDFObjectives/hypothesis: To evaluate the application and advantages of coblation tonsillectomy with inferior pole capsule preservation in pediatric patients with tonsillar hypertrophy and recurrent tonsillitis.
Study Design: Retrospective chart review.
Methods: A total of 726 children who were diagnosed with either tonsillar hypertrophy or recurrent tonsillitis were included.
Supramolecular organogels are soft materials comprised of low-molecular-mass organic gelators (LMOGs) and organic liquids. Owning to their unique supramolecular structures and potential applications, LMOGs have attracted wide attention from chemists and biochemists. A new "superorganogel" system based on dicarboxylic acids and primary alkyl amines (R-NH) from the formation of organogels is achieved in various organic media including strong and weak polar solvents.
View Article and Find Full Text PDFBackground: The increasing occurrence of radiation-induced second primary squamous cell carcinoma of the oral cavity (RISCCO) after radiotherapy for nasopharyngeal carcinoma (NPC) has become a noteworthy complication that can influence long-term survival. This study aimed to analyze the associations of clinicopathologic characteristics with prognostic factors among patients who developed RISCCO after radiotherapy for NPC.
Methods: A total of 41,446 NPC patients admitted to Sun Yat-sen University Cancer Center (SYSUCC) between August 1989 and January 2019 were reviewed.
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
February 2020
The aim of this study is to explore the application and advantages of combined intrathecal and extrathecal hypothermic plasma tonsillectomy in reducing intraoperative and postoperative hemorrhage in OSA children. We retrospectively reviewed 726 cases who were diagnosed as OSA. All patients were divided into two groups according to the surgical method: 320 cases by total tonsillectomy and 406 cases by combined extracapsular and intracapsular tonsillectomy.
View Article and Find Full Text PDFBackground: The increasing incidence of radiation-induced osteosarcoma of the maxilla and mandible (RIOSM) has become a significant problem that can limit long-term survival. The purpose of this study was to analyze the association of clinicopathologic characteristics with treatment outcomes and prognostic factors of patients who developed RIOSM after undergoing radiotherapy for nasopharyngeal carcinoma (NPC).
Methods: We reviewed the medical records of 53,760 NPC patients admitted to Sun Yat-sen University Cancer Center during the period August 1964 to August 2012.
The N-doped porous carbon monoliths prepared by direct carbonization of IRMOF-3, through an in situ activation and self-templating process, were found to exhibit significantly enhanced performance for the selective adsorption of CO2 compared to pristine IRMOF-3. The transformation from the microporous structure to the meso-macroporous structure opens the pathway for CO2 to more easily access the nitrogen anchors.
View Article and Find Full Text PDFCurrently, the design and construction of an intelligent stimuli-responsive gel system is still a significant challenge. We present here a new gel system from which the formation of heat-set gels, conventional gels and irreversible heat-set gels can be achieved in aromatic solvents. This gel system is based on two-component gelators containing a succinamic acid derivative (SAD) and a primary alkyl amine (R-NH2).
View Article and Find Full Text PDFA rare (3,4,5)-connected self-interpenetrated metal-organic framework with an O-atom lined pore surface has been constructed from Zn(II) and H4L (H4L = 5,5'-(1,3,6,8-tetraoxobenzo[lmn][3,8]phenanthroline-2,7(1H,3H,6H,8H)diyl)-diisophthalic acid), which features an unprecedented 1D + 2D → 3D self-interpenetrated array and shows good controlled drug release properties.
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