Publications by authors named "Lien Vandaele"
Aims: Little is known about dynamic changes of the left atrial (LA) substrate over time in patients with atrial fibrillation (AF). This study aims to evaluate substrate changes following pulmonary vein isolation (PVI).
Methods And Results: In our prospective observational study, consecutive patients undergoing first PVI-only and redo ablation were included.
Gender-related differences have been reported in patients who underwent pulmonary vein isolation (PVI). Atrial substrate plays a role in the outcomes after ablation but gender-related differences in atrial substrate have never been described in detail. We sought to analyze gender-related differences in atrial remodeling (spontaneous low-voltage zones [LVZs]) and their clinical relevance after PVI.
View Article and Find Full Text PDFBackground: The benefit of an anterior mitral line (AML) in patients with persistent atrial fibrillation (AF) and anterior atrial scar undergoing ablation has never been investigated.
Objective: The purpose of this study was to evaluate the outcomes of AML in addition to standard treatment compared to standard treatment alone (no AML) in this subset of patients.
Methods: Patients with persistent AF and anterior low-voltage zone (LVZ) treated with AML in 3 centers were retrospectively enrolled.
Characterization of Atrial Substrate to Predict the Success of Pulmonary Vein Isolation: The Prospective, Multicenter MASH-AF II (Multipolar Atrial Substrate High Density Mapping in Atrial Fibrillation) Study.
J Am Heart Assoc
January 2023
Article Synopsis
- A study analyzed the relationship between low-voltage zones (LVZs) in the left atrium and the recurrence of atrial fibrillation (AF) in patients who underwent pulmonary vein isolation, finding that a higher percentage of LVZs correlated with increased recurrence rates.
- The research involved 262 patients, showing that more than 5% LVZ in paroxysmal AF and over 15% in persistent AF significantly raised the risk of AF recurrence within 28 months.
- The findings suggest that not all LVZs are equally significant in predicting outcomes; some patients may experience AF recurrence without the expected volume of LVZs, indicating complex underlying heart tissue changes.
Introduction: Different methods are used for atrial fibrillation (AF) cycle length (CL) measurement with variable results. Previous studies of pulmonary vein (PV) CL measurement showed contradictory results on predicting PV isolation (PVI) efficacy. A novel simple method of measuring the average of 10 consecutive Fastest Atrial Repetitive Similar morphology signal (FARS )-CL to characterize local atrial activity rate was evaluated prospectively.
View Article and Find Full Text PDFObjectives: This study investigated whether real-world use of contemporary technologies changed pulmonary vein (PV) reconnection and redo pulmonary vein isolation (PVI) procedure frequencies.
Background: Previous studies consistently reported that following PVI recurrence of PV conduction is observed in >80% of patients.
Methods: Consecutive patients undergoing 529 first and/or redo radiofrequency point-by-point PVI between January 2013 and December 2016 were included.