Publications by authors named "Liege M A Carvalho"

Article Synopsis
  • Zika virus (ZIKV) is linked to serious birth defects, making it tough to diagnose infections during pregnancy; this study focused on tracking neutralizing antibodies in infants born to mothers who had confirmed ZIKV infections.
  • A total of 98 neonates were tested for ZIKV neutralizing antibodies (nAb) while also checking for evidence of vertical transmission and any clinical abnormalities over two years.
  • The results showed that many infants had evidence of vertical transmission but did not produce ZIKV nAb, challenging its usefulness for diagnosing congenital infections and raising questions about their susceptibility to future infections.
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Background: The signs and symptoms of Zika virus infection are usually mild and self-limited. However, the disease has been linked to neurological complications such as Guillain-Barré syndrome and peripheral nerve involvement, and also to abortion and fetal deaths due to vertical transmission, resulting in various congenital malformations in newborns, including microcephaly. This review aimed to describe the o signs and symptoms that characterize the congenital Zika syndrome.

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A comprehensive cohort study including an entomological surveillance component can contribute to our knowledge of clinical aspects and transmission patterns of arbovirosis. This article describes the implementation of a populational-based birth cohort study that included an entomological surveillance component, and its associated challenges in a low-income community of Rio de Janeiro, Brazil. The participants were recruited in two periods: from 2012 to 2014, and from 2015 to 2017.

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The objective of the present study was to estimate the prevalence of soil-transmitted helminthiasis and evaluate the sanitary conditions and the role of a mass treatment campaign for control of these infections in Santa Isabel do Rio Negro. A cross-sectional survey was carried out in 2002, to obtain data related to the sanitary conditions of the population and fecal samples for parasitological examination in 308 individuals, followed by a mass treatment with albendazole or mebendazole with coverage of 83% of the city population in 2003. A new survey was carried out in 2004, involving 214 individuals, for comparison of the prevalences of intestinal parasitosis before and after the mass treatment.

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