Publications by authors named "Liefeng Cai"
Eur J Pharm Sci
July 2021
Article Synopsis
- The study aimed to understand how daptomycin behaves in kidney transplant patients in China, focusing on the population pharmacokinetics (PPK) of the drug.
- A mixed-effects model was used to analyze data from 49 patients, revealing that factors like glomerular filtration rate (GFR) and body weight significantly influence the drug's clearance and distribution.
- The research established a dosing regimen for daptomycin based on GFR and weight, providing guidelines to personalize treatment and minimize toxicity for kidney transplant recipients.
