Publications by authors named "Liebin Zhao"

Background: Previous studies have shown that electrocardiographic (ECG) alarms have high sensitivity and low specificity, have underreported adverse events, and may cause neonatal intensive care unit (NICU) staff fatigue or alarm ignoring. Moreover, prolonged noise stimuli in hospitalized neonates can disrupt neonatal development.

Objective: The aim of the study is to conduct a nationwide, multicenter, large-sample cross-sectional survey to identify current practices and investigate the decision-making requirements of health care providers regarding ECG alarms.

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Article Synopsis
  • The rapid growth of digital health presents opportunities for elderly patients with chronic diseases, but a digital divide limits their use of digital health technologies (DHTs).
  • The study examined factors affecting DHT adoption among older adults, extending the UTAUT theory to include technology anxiety and demographic predictors.
  • Findings suggest that improving facilitating conditions and usage experiences, along with targeted education and support, can reduce technology anxiety and enhance the acceptance of DHTs in this vulnerable group.
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Leukemia classification relies on a detailed cytomorphological examination of Bone Marrow (BM) smear. However, applying existing deep-learning methods to it is facing two significant limitations. Firstly, these methods require large-scale datasets with expert annotations at the cell level for good results and typically suffer from poor generalization.

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Background: To promote the shared decision-making (SDM) between patients and doctors in pediatric outpatient departments, this study was designed to validate artificial intelligence (AI) -initiated medical tests for children with fever.

Methods: We designed an AI model, named Xiaoyi, to suggest necessary tests for a febrile child before visiting a pediatric outpatient clinic. We calculated the sensitivity, specificity, and F1 score to evaluate the efficacy of Xiaoyi's recommendations.

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Objective: This study aimed to investigate the composite effects of different kinds of phthalates on depression risk in the U.S population.

Methods: 11731 participants were included from the National Health and Nutrition Examination Survey (NHANES), a national cross-sectional survey.

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It has proved that the auscultation of respiratory sound has advantage in early respiratory diagnosis. Various methods have been raised to perform automatic respiratory sound analysis to reduce subjective diagnosis and physicians' workload. However, these methods highly rely on the quality of respiratory sound database.

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Introduction: Complicated outpatient procedures are associated with excessive paperwork and long waiting times. We aimed to shorten queuing times and improve visiting satisfaction.

Methods: We developed an artificial intelligence (AI)-assisted program named .

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A wearable electrocardiogram (ECG) device is an effective tool for managing cardiovascular diseases. This paper presents a low power clinician-like cardiac arrhythmia watchdog (CAW) for wearable ECG devices. The CAW is based on a novel P-QRS-T detection algorithm that makes use of clinical features to identify abnormalities.

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Objective: This study aimed to establish a pediatric lower respiratory tract infections (PLRTIs) database based on the structured electronic medical records (SEMRs), to provide a brief overview and the usage process of the SEMRs and the database.

Methods: All the medical information is recorded by a clinical information system developed by Eureka Systems Company. A plugin of the software was used to set the properties of items of the SEMR.

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Objective: This study aimed to evaluate the relationship between daily dietary intake of fiber (DDIF) and short sleep duration (SSD) in the presence of di(2-ethylhexyl) phthalate.

Methods: Data of 13,634 participants in this study were collected from the National Health and Nutrition Examination Survey (NHANES). The sum of urinary mono-2-ethyl-5-carboxypentyl phthalate, mono-(2-ethyl-5-hydroxyhexyl) phthalate, mono-(2-ethyl)-hexyl phthalate, and mono-(2-ethyl-5-oxohexyl) phthalate was used to evaluate the level of di(2-ethylhexyl) phthalate (DEHP) exposure.

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Article Synopsis
  • * High DDIR (≥1.8 mg/day) was linked to less lung impairment despite high DBP exposure, as seen with urinary mono-benzyl phthalate (MBP) levels.
  • * The results suggested that individuals with low DDIR faced significantly higher risks of lung function impairment and neutrophil levels with higher DBP exposure, indicating that riboflavin might help mitigate these effects.
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Secundum atrial septal defect (ASD) is one of the most common congenital heart diseases (CHDs). This study aims to evaluate the feasibility and accuracy of automatic detection of ASD in children based on color Doppler echocardiographic images using convolutional neural networks. In this study, we propose a fully automatic detection system for ASD, which includes three stages.

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Standard echocardiographic view recognition is a prerequisite for automatic diagnosis of congenital heart defects (CHDs). This study aims to evaluate the feasibility and accuracy of standard echocardiographic view recognition in the diagnosis of CHDs in children using convolutional neural networks (CNNs). A new deep learning-based neural network method was proposed to automatically and efficiently identify commonly used standard echocardiographic views.

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Aim: This study examined the effect on pediatric nursing handover quality and efficiency when a standardized e-handover system was implemented.

Background: Handover quality is an important aspect of nursing quality management; however, handover quality among nursing staff is poor.

Methods: A prospective interventional study was carried out in a general pediatrics ward from December 2019 to November 2020.

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Objectives: This study aimed to assess the associations of caesarean delivery (CD) with risk of wheezing diseases and changes of immune cells in children.

Design: The cross-sectional study was conducted between May, 2020 and April, 2021.

Setting And Participants: The study was conducted in Shanghai Children's Medical Center, Shanghai, China.

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Artificial intelligence (AI) has been deeply applied in the medical field and has shown broad application prospects. Pre-consultation system is an important supplement to the traditional face-to-face consultation. The combination of the AI and the pre-consultation system can help to raise the efficiency of the clinical work.

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Objectives: We sought to develop a nomogram to predict Mycoplasma pneumoniae (Mp) infection among hospitalized children with community-acquired pneumonia (CAP) and compare it with another model developed from age and duration of fever.

Methods: Data on 5904 CAP children who were enrolled at Shanghai Children's Medical Center were retrospectively collected and divided into a training set (n = 4133) and a validation set (n = 1771). The model's performance was determined by concordance index (C-index), calibration curves, Brier scores, and decision curve analyses (DCAs).

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. Auscultation of lung sound plays an important role in the early diagnosis of lung diseases. This work aims to develop an automated adventitious lung sound detection method to reduce the workload of physicians.

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Leukemia is the most common malignancy affecting children. The morphologic analysis of bone marrow smears is an important initial step for diagnosis. Recent publications demonstrated that artificial intelligence is able to classify blood cells but a long way from clinical use.

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Objectives: The purpose of this article was to establish and validate clinically applicable septic shock early warning model (SSEW model) that can identify septic shock in hospitalized children with onco-hematological malignancies accompanied with fever or neutropenia.

Methods: Data from EMRs were collected from hospitalized pediatric patients with hematological and oncological disease at Shanghai Children's Medical Center. Medical records of patients (>30 days and <19 years old) with fever (≥38°C) or absolute neutrophil count (ANC) below 1.

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To establish a structured and integrated platform of clinical data and biobank data, and a client to retrieve these data. Initially, the hospital information system (HIS) and biobank information system (BIS) were integrated through the patients' ID numbers. Then, natural language processing (NLP) was used to process the integrated unstructured clinical information.

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Article Synopsis
  • - The study assessed an AI algorithm's effectiveness in detecting breath sounds in children with pulmonary diseases, using data collected at the Shanghai Children's Medical Center from May to December 2019.
  • - A total of 112 children contributed 672 breath sound recordings, with the AI showing a detection accuracy of 77.7%, significantly outperforming general pediatricians who had an accuracy of 59.9%.
  • - Results indicated that the AI's performance varied by patient age, with the highest accuracy (81.3%) observed in children under 12 months, especially in identifying specific sounds like crackles and wheezes.
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Background: Many studies suggest that patient satisfaction is significantly negatively correlated with the waiting time. A well-designed healthcare system should not keep patients waiting too long for an appointment and consultation. However, in China, patients spend notable time waiting, and the actual time spent on diagnosis and treatment in the consulting room is comparatively less.

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In order to investigate the clinical features of pregnant women and their neonates with coronavirus disease 2019 (COVID-19) and the evidence of vertical transmission of COVID-19, we retrieved studies included in PubMed, Medline and Chinese databases from January 1, 2000 to October 25, 2020 using relevant terms, such as 'COVID-19', 'vertical transmission' . in 'Title/Abstract'. Case reports and case series were included according to the inclusion and exclusion criteria.

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Article Synopsis
  • COVID-19 infection rates in children are lower than in adults, but the reasons for this difference remain unclear.
  • A study involving 248 confirmed and 56 suspected pediatric COVID-19 cases in two hospitals examined associations between initial symptoms, age, and vaccinations, finding that many children were asymptomatic.
  • The results indicated no significant difference in symptom severity between children vaccinated with BCG and those without, suggesting that immune function maturity may influence symptom severity in young patients.
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