Publications by authors named "Lie-Wei Luo"
Article Synopsis
- A bioinformatic analysis revealed 29 gene ontology terms related to immune function and gene transcription in the differentially expressed genes (DEGs) from NGAL overexpressing cells.
- The study identified unique transcription factors for both upregulated and downregulated DEGs, enhancing the understanding of NGAL's role in esophageal squamous cell carcinoma.
Background: Fascin, an actin-bundling protein forming actin bundles including filopodia and stress fibers, is overexpressed in multiple human epithelial cancers including esophageal squamous cell carcinoma (ESCC). Previously we conducted a microarray experiment to analyze fascin knockdown by RNAi in ESCC.
Method: In this study, the differentially expressed genes from mRNA expression profilomg of fascin knockdown were analyzed by multiple bioinformatics methods for a comprehensive understanding of the role of fascin.
A number of snake venom thrombin-like enzymes (TLEs) have already been characterized. Some TLEs play significant roles in vessel injury hemostasis. A novel TLE (Agacutase) was purified from Deinagkistrodon acutus snake venom by the means of Sephadex G-75, DEAE-Sepharose FF, and Sephadex G-25 column chromatography.
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