Serial left ventricular ejection fraction in acute myocardial infarction by cross-sectional echocardiography: correlation of changing ejection fraction with clinical course.

Left ventricular volume and ejection fraction were measured in 22 survivors of acute myocardial infarction by means of two-dimensional echocardiography and using a Simpson's rule algorithm. Ten of the 22 patients experienced complications. For the group as a whole, there were no significant trends in left ventricular volume and ejection fraction between the first and third days and the third month after infarction.

Measurement of left ventricular ejection fraction after acute myocardial infarction. A serial cross sectional echocardiographic study.

Left ventricular ejection fraction was assessed by biplane cross sectional echocardiography in 65 patients with a first acute myocardial infarction on the first day. In 30 patients (group 1) measurements were repeated on the third day and in another 35 patients (group 2) at three months. Changes in ejection fraction of 0.

Early two-dimensional echocardiographic measurement of left ventricular ejection fraction in acute myocardial infarction.

Left ventricular volume and ejection fraction were measured by 2-dimensional echocardiography from 2 orthogonal apical long axis views in 90 patients admitted with acute transmural myocardial infarction. Results were correlated with worst Killip class during hospital stay, enzymatic infarct size (peak CK-MB) and mortality. We used two algorithms, a biplane area-length algorithm and a modification of Simpson's rule.

Immediate and longer-term effects of nicardipine, at rest and during exercise, in patients with coronary artery disease.

Haemodynamic effects of nicardipine were studied in 12 patients with coronary artery disease. After 10 mg i.v.

Diet and pump-treated diabetes: a long-term follow-up.

Long-term effects of a liberalized diabetes diet without meal-planning and food-exchange were investigated in lean type-I diabetic patients treated by continuous subcutaneous insulin infusion (CSII). Food intake, body weight, HbA1c levels and serum lipids were recorded during conventional s.c.

Thallium-201 scanning to decide CCU admission in patients with non-diagnostic electrocardiograms.

To determine the value of thallium-201 scintigraphy as a decisive factor in admission policy for patients with acute chest pain and nondiagnostic electrocardiograms, we undertook a prospective study in 149 such patients. The interval between pain and scan never exceeded 12 hr. Of 57 patients in whom a defect was seen, 34 had an acute infarction, 7 developed infarction within 2 months, and in 11 coronary heart disease was proven by angiography or strongly suggested by stress tests (ECG and thallium-201 scan).

The definition of myocardial infarction during aortocoronary bypass surgery.

In a study of 392 aortocoronary bypass (CABG) patients, we found 16 patients with a postoperative new Q wave, 29 patients with new intraventricular conduction disturbance, 17 patients with cardiogenic shock, and 14 patients with excessive CK-MB activity. Those criteria were considered as diagnostic of perioperative acute myocardial infarction (AMI). Listing the 392 patients in a Venn diagram: five patients had three positive criteria, eight had two, 43 had one, and 336 had none.

Comparison of two-dimensional echocardiography with radionuclide angiography during dynamic exercise for the detection of coronary artery disease.

Two-dimensional echocardiography (2DE) was performed during 30-degree left lateral decubitus bicycle exercise in 52 patients who underwent cardiac catheterization for suspected coronary artery disease (CAD). Adequate echocardiograms were obtained in 39 patients (75%). Thirty-five of these patients underwent radionuclide angiography (RNA) with the same exercise protocol as for echocardiography.

Risk of operative mortality in surgery for coronary heart disease (a multiple regression analysis of perioperative hemodynamic and electrocardiographic data).

Using multiple regression analysis, we examined perioperative hemodynamic and electrocardiographic variables as predictors of operative mortality in surgery for coronary heart disease. Data were first analyzed as univariates and, if significantly related to mortality, they were subjected to stepwise logistic multivariate regression analysis. The preoperative predictor variables were: heart rate, ventricular arrhythmia and ST-T shift.

beta-Blockade and acute myocardial infarction.

Results from experimental and clinical studies suggest that beta-blockade may have beneficial effects in acute myocardial infarction. These effects relate to decrease of cardiac work and improvement of metabolism without deleterious effects on perfusion of the ischemic myocardium. Several well designed randomized controlled studies with beta blockers have been carried out in the acute phase of myocardial infarction.

Effects of cardiac rehabilitation after myocardial infarction: changes in coronary risk factors and long-term prognosis.

Prognosis during 5 years of follow-up after first myocardial infarction (MI) in a group of men (aged 40 to 55 years) was related to risk factors determined at the time of MI. Progression of coronary artery disease (CAD) was measured by the occurrence of severe angina pectoris, recurrent myocardial infarction, and cardiac death. Only smoking and serum cholesterol level influenced prognosis.

Left ventricular thrombus following acute myocardial infarction: a prospective serial echocardiographic study of 96 patients.

In a prospective serial study of 96 patients with acute myocardial infarction, two dimensional echocardiography identified left ventricular thrombus in 18 patients. The majority of thrombi (15) developed within the first 4 days after admission. In three patients thrombi were identified for the first time 4 months after the acute episode.

Infarct size estimation from serial CK MB determinations: peak activity and predictability.

In 198 patients with acute myocardial infarction serial measurements of plasma creatine kinase isoenzyme MB (CK MB) were performed at four hour intervals. In every patient, maximal CK MB activity (peak activity) was compared with calculated total release per litre plasma. In 28 patients (group 1) sufficient plasma samples were available for calculation of the apparent first order inactivation constant kd.

Two dimensional echocardiography in the diagnosis of left ventricular thrombus. A prospective study of 67 patients with anatomic validation.

Seventy-two patients, in whom a high prevalence of left ventricular thrombus (LVT) was anticipated, were studied prospectively by two-dimensional echocardiography (2DE). Adequate echocardiograms were obtained in 67 patients (93 percent). Presence or absence of LVT was verified at surgery in 51 patients undergoing aneurysmectomy, and at autopsy in 16 patients dying from acute myocardial infarction.

Serologic evidence of ureaplasma urealyticum infection in women with spontaneous pregnancy loss.

Among 71 couples with histories of pregnancy wastage, 84.5% were colonized with Ureaplasma urealyticum and/or Mycoplasma hominis; whereas in couples with successful deliveries the incidence was 25.4%.

Efficacy of antibiotic therapy in preventing spontaneous pregnancy loss among couples colonized with genital mycoplasmas.

Evidence suggests that genital mycoplasmas play a role in spontaneous abortion, prematurity, and perinatal morbidity and mortality rate. Since these organisms are sensitive to antibiotics, three treatment regimens were assessed for efficacy in preventing spontaneous pregnancy loss. The pregnancy loss rate was significantly reduced from 96% to 47.

Identification and distribution of Echinostoma lindoense, E. audyi and E. revolutum (Trematoda; Echinostomatidae).

The closely related Echinostoma lindoense, E. audyi and E. revolutum can be differentiated by morphological characteristics of their adults and cercariae.

The ultrastructure of the amebocyte-producing organ in Biomphalaria glabrata.

The amebocyte-producing organ (APO) in normal and echinostome-sensitized Biomphalaria glabrata was studied at the ultrastructural level. The APO in unexposed snails consists of small clusters of primary ameboblasts resting on the epithelial cells lining the pericardium. The ameboblasts are held in a loose reticulum formed by extensions from smooth muscle and few fibroblastic cells.