The cross-linking sites and structure of protein-polyphenol complexes are susceptible to the type, structure, weight of polyphenols under nonthermal process. The low bioavailability and poor gastrointestinal instability of curcumin (CUR) hampers its application. Hence, changes in binding mechanism, structural and functional properties between β-lactoglobulin (β-LG) with two different configurations of chlorogenic acids (neochlorogenic acids (3-CQA) and cryptochlorogenic acids (4-CQA) by non-covalent binding under ultrasonic treatment, and the potential capacity for loading CUR were researched.
View Article and Find Full Text PDFBackground: Renal dysfunction has been identified as a risk factor for both stroke and bleeding events in atrial fibrillation (AF) patients, yet the mechanisms remain unclear. We examines the connection between fine fibrillatory wave and estimated glomerular filtration rate (eGFR) decline, alongside chronic kidney disease (CKD).
Methods: Persistent AF patients admitted to Jinan University's First Affiliated Hospital from January 2019 to June 2023 were enrolled.
Objective: Evidence on the association of oxidative balance score (OBS) and visceral adiposity index (VAI) with risk of ischaemic heart disease (IHD) is limited. We aimed to explore the association of OBS and VAI with risk of IHD, and then examined their potential interactive effects.
Design: A cross-sectional study.
Front Cardiovasc Med
November 2022
Objective: To examine the incidence of cardiomyopathy including both alcoholic cardiomyopathy (AC) and other cardiomyopathy (OC) in 204 nations and regions over the 1990-2019 period.
Methods: The present study was conducted using data derived from the GBD 2019 study coordinated by the Institute for Health Metrics and Evaluation (IHME). The GBD 2019 study included epidemiological data pertaining to 369 diseases/injuries, 286 causes of death, and 87 risk factors in 204 nations and regions.
To reveal the basic characteristics and controlling factors of water quality change in the project Wenyu to Chaobai reclaimed water diversion, the water quality in the study area was monitored for one year at seven monitoring sites. Inverse geochemical models of the statistical groups were developed using PHREEQC to elucidate the hydrochemistry characteristics of reclaimed water and the factors. The monitoring results indicated that nitrogen and phosphorus contents were significantly reduced along the river mainly caused by seasonal and location variation.
View Article and Find Full Text PDFTo study the groundwater polluted by nitrate in a landfill site in Beijing, with the pump-and-treat technology, genetic algorithms (GA) and simulated annealing (SA) were used to optimize the cases of 18 planned pumping wells in the groundwater nitrate plume. The optimization method was run to determine the minimum total costs, as a result of the optimal number of wells with the optimal locations and pumping rates. The results of optimization showed that, both GA and SA optimization conditions could reach the desired results, which means that the concentration of nitrate could be reduced to 10 mg x L(-1) after 100 days pumping.
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