Publications by authors named "Lidys Rivera"
Background: Cystic Fibrosis (CF) is the most common life limiting genetic disorder, characterized by chronic respiratory failure secondary to inflammation and chronic bacterial lung infection. Pseudomonas aeruginosa lung infection is associated with more severe lung disease and rapid progression of respiratory failure when compared to Staphylococcus aureus infection. We hypothesized that a specific signature of epigenetic factors targeting specific gene transcripts contributes to the increased morbidity seen in CF patients with chronic Pseudomonas infection.
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- Bronchopulmonary dysplasia (BPD) is a chronic lung condition affecting very-low-birth-weight preterm infants, linked to inadequate lung development and a reliance on supplemental oxygen.
- The increasing incidence of BPD has been attributed to improved survival rates of these infants, but diagnosing and managing the condition remains challenging due to the lack of reliable biomarkers and the similarity of symptoms with other diseases like pulmonary hypertension (PH).
- Current research is focusing on developing prevention strategies, identifying potential biomarkers for early detection and targeting experimental therapies, while also summarizing guidelines for BPD and PH diagnosis and management.