A nano-copper particle-modified zinc anode as a protective coating enables dendrite-free aqueous zinc-ion batteries.

Aqueous zinc-ion batteries (AZIBs) have become one of the hotspots in large-scale energy storage due to their advantages of high safety, low cost, and environmental friendliness. However, the metallic Zn anode is prone to dendritic growth and electrochemical corrosion on the surface during cycling, posing a serious challenge to the cycling life of AZIBs. Herein, a simple, low-cost and suitable for mass production method is reported to construct an anti-corrosive nano-copper particle protective coating on the surface of a metallic zinc (Cu-Zn) anode.

Clinical features of MOGAD with brainstem involvement in the initial attack versus NMOSD and MS.

Objective: To assess the characteristics of Myelin oligodendrocyte glycoprotein (MOG) antibody-associated disorder (MOGAD) with brainstem involvement in the first event (BSIFE) and make comparisons with aquaporin-4-IgG seropositive neuromyelitis optica spectrum disorder (AQP4-IgG-NMOSD) and multiple sclerosis (MS).

Methods: From 2017 to 2022, this study identified MOG-IgG-positive patients with brainstem or both brainstem and cerebellum lesions in the first episode. As a comparison group, AQP4-IgG-NMOSD (n = 30) and MS (n = 30) patients with BSIFE were enroled.

Central sleep apnea and daytime sleepiness in Niemann-Pick type C disease: a report of 2 cases.

Unlabelled: Niemann-Pick disease type C (NPC) is an autosomal recessive hereditary disease in which sphingomyelin and cholesterol are deposited in various organs of the body. The clinical manifestations of NPC include neurologic symptoms and cataplexy; other symptoms related to sleep have seldom been reported. One previous study described various sleep disorders including chronic insomnia, obstructive sleep apnea, restless legs syndrome, and rapid eye movement sleep behavior disorder, thus suggesting that sleep disorders in patients with NPC are more prevalent than previously thought and warrant close attention.

Uniform Bi-BiO nanoparticles/reduced graphene oxide composites for high-performance aqueous alkaline batteries.

Aqueous alkaline batteries (AABs) with the merits of both high energy density and power density have emerged as one of the most promising candidates for the new generation of energy storage devices, while their practical applications are still limited by the lack of high-performance electrode materials, especially for the anode materials. Herein, metallic bismuth-bismuth oxide nanoparticles (Bi-BiO), with numerous heterogeneous interfaces, are successfully anchored and uniformly distributed on reduced graphene oxide (rGO) sheets. When Bi-BiO/rGO-20 electrode is used as the anode material for an AAB, it shows a high specific capacity of 288.

Minimal Manifestation Status Indicates a Stable State in Myasthenia Gravis: A Quantitative Study.

Introduction: Minimal manifestation (MM) or better was recommended as the treatment goal for myasthenia gravis (MG). The sustainability of this status has not been described quantitatively in patients who had attained or are close to it.

Methods: Patients who were with no or slight impact on daily living were recruited and followed at baseline and 3, 6, and 12 months.

Characteristics of Patients with Meningeal Carcinomatosis Combined with Myelopathy.

Objective: To explore the disease manifestations and radiological characteristics of patients with meningeal carcinomatosis (MC) combined with myelopathy.

Patients And Methods: The detailed medical information of patients who suffered from MC with myelopathy in record system were collected and reviewed.

Results: In these patients, five cases were male and two cases were female.

Therapeutic Effects of Batoclimab in Chinese Patients with Generalized Myasthenia Gravis: A Double-Blinded, Randomized, Placebo-Controlled Phase II Study.

Introduction: We investigated the safety and explore potential efficacy of batoclimab administered subcutaneously in Chinese patients with generalized myasthenia gravis (gMG).

Methods: A randomized, double-blinded, placebo-controlled, parallel phase II study was conducted. First, in the double-blinded treatment period, eligible patients received batoclimab (680 mg), batoclimab (340 mg), or placebo on days 1, 8, 15, 22, 29, and 36.

Transcranial alternating current stimulation for treating depression: a randomized controlled trial.

Treatment of depression with antidepressants is partly effective. Transcranial alternating current stimulation can provide a non-pharmacological alternative for adult patients with major depressive disorder. However, no study has used the stimulation to treat first-episode and drug-naïve patients with major depressive disorder.

Immune-Mediated Cerebellar Ataxia Associated With Neuronal Surface Antibodies.

Background: Immune-mediated cerebellar ataxias (IMCAs) are common in paraneoplastic cerebellar degeneration (PCD) but rarely occur in patients with neuronal surface antibodies (NSAbs). Although cerebellar ataxias (CAs) associated with anti-NMDAR and anti-CASPR2 have been reported in a few cases, they have never been studied systematically. This study aimed to analyze the characteristics of anti-NSAbs-associated CAs.

Sensorineural Hearing Loss as the Prominent Symptom in Meningeal Carcinomatosis.

Sensorineural hearing loss (SNHL) has been reported rarely in patients with meningeal carcinomatosis (MC). We summarized the clinical data of eight MC patients with SNHL and 35 patients reported from publications. In the eight patients with SNHL, the medium onset age was 48 (range from 37 to 66) years and six (75%) were male.

Clinical Characteristics and Management of Cerebral Venous Sinus Thrombosis in Patients with Essential Thrombocythemia.

Background And Objective: Essential thrombocythemia (ET) is a rare cause of cerebral venous sinus thrombosis (CVST). Analysis of the risk factors and treatment therapies of CVST in ET has yielded controversial findings.

Subjects And Methods: We retrospectively investigated the clinical characteristics of CVST events in ET and compared baseline characteristics, causative factors, hematological effects, and treatments between ET patients with and without CVST.

Staphylococcus aureus meningitis complicated with intracranial hemorrhage and cerebral infarction: a case report.

Purpose: The case with staphylococcus aureus meningitis accompanied by intracranial hemorrhage and cerebral infarction is very rare and cerebrovascular complications are often associated with poor outcome.

Materials And Methods: We describe the clinical characteristics and laboratory data of a patient with meningitis accompanied by cerebrovascular complications.

Results: The patient, a young male, was admitted to hospital with 3 weeks of fever, 10 days of slow reaction and 2 days of left limb strength decline.

Clinical characteristics of patients with paraneoplastic myelopathy.

Paraneoplastic myelopathy is rare paraneoplastic neurological syndromes. We reviewed patients through medical records system and screened patients who presented with myelopathy, and/or coexisting cancer, and/or onconeural antibodies. Nine patients were identified as paraneoplastic myelopathy presenting with progressive subacute (2/9) or insidious (7/9) myelopathy.

Diagnosis and treatment of dementia in neurology outpatient departments of general hospitals in China.

Introduction: The status of dementia diagnosis and treatment of neurology outpatients in general hospitals in China remains unclear.

Methods: From neurology outpatients at 36 randomly selected hospitals, we first collected baseline data concerning the number of dementia doctors, memory clinics, and patients diagnosed with dementia. In stage 2, we intervened based on drawbacks discovered in stage 1, implementing a dementia initiative program.

(R)-3-oxobutyl 3-hydroxybutanoate (OBHB) induces hyperketonemiain Alzheimer's disease.

The present study demonstrates the effect of (R)-3-oxobutyl 3-hydroxybutanoate (OBHB) on hyperketonemia in 2 patients with Alzheimer's disease dementia who were performed a mini-mental state examination score of above 11 and 10. The patients were treated with OBHB for 24 months and received usual diet. The patients were administered 15 g of OBHB three times per day for two days.

Prognostic value of copeptin in patients with acute stroke.

Context: There is a need to improve stroke care through the prompt identification of stroke patients at increased risk of an adverse outcome.

Objective: To evaluate the prognostic value of copeptin in patients with stroke.

Methods: We systematically searched PubMed and Embase for relevant studies.

[Clinical diagnosis and analysis of cerebral cortical venous thrombosis].

Objective: To investigate the clinical and radiological characteristics of cortical vein thrombosis for early diagnosis and treatment.

Methods: Retrospective analysis was carried out with the clinical cases of cortical vein thrombosis in 2010. The symptoms, sign, neuroimaging were analyzed and related literatures were reviewed.

[The influence of induced hypertension in acute phase on focal cerebral ischemia injury].

Objective: To study the influence of induced hypertension in acute phase on the infarct volume and regional cerebral blood flow (rCBF) during focal cerebral ischemia in rats.

Methods: The adult rat's models of permanent focal cerebral ischemia were established by permanent middle artery occlusion. Thirty-six rats were divided six groups.