Publications by authors named "Lidiani F Santana"

Article Synopsis
  • This study assessed the effects of ethanolic and aqueous extracts from a plant's bark on mice fed a high-fat diet and analyzed the extracts' chemical composition.
  • The results indicated that while the aqueous extract had better antioxidant properties, neither extract significantly affected weight gain or fat accumulation, but they did decrease food intake.
  • Additionally, the extracts increased leptin levels, which might promote feelings of fullness, but negatively impacted other inflammatory and hormonal markers, showing no effective treatment for diet-related metabolic issues.
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Oncological patients show intense catabolic activity, as well as a susceptibility to higher nutritional risk and clinical complications. Thus, tools are used for monitoring prognosis. Our objective was to analyze the nutrition prognosis of patients who underwent radiotherapy, correlating it with outcomes and complications.

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L. (grapevine) is a perennial plant of the Vitaceae family that is widely used to produce grapes and wines. Grape seed oil is rich in fatty acids such as linoleic acid (65-75%), vitamin E (50 mg), and phytosterols in addition to phenolic compounds, such as catechins (414 mg), epicatechins (130.

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Article Synopsis
  • Maternal dietary choices, particularly the intake of polyunsaturated fatty acids (PUFAs), and gut microbiota influence fetal brain development and may play a role in Autism Spectrum Disorder (ASD) risk.
  • Higher consumption of linoleic acid (LA, a n-6 PUFA) is linked to negative effects on gut health and increased inflammation, whereas α-linolenic acid (ALA, a n-3 PUFA) can promote gut health and reduce inflammation.
  • Observational studies suggest that a high intake of n-3 PUFAs, like fish, benefits infant neurodevelopment, indicating that proper maternal nutrition could help lower ASD risk, but more controlled research is needed to determine effective supplementation strategies. *
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The study of medicinal plants, such as the genus (Clusiaceae), in the treatment of non-communicable chronic diseases has aroused the interest of researchers. However, there are no studies in the literature that have investigated the effects of in experimental models of obesity for possible metabolic alterations. Swiss mice receiving a high-fat diet were supplemented with aqueous or ethanolic extract of at doses of 200 or 400 mg/kg/day.

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Background: Studies indicate that different parts of Linn have nutritional properties that mean it can be used as an adjuvant for the treatment of various pathologies.

Methods: The fatty acid composition of the oil extracted from the seeds of Linn was evaluated by gas chromatography, and an acute toxicity test was performed. For the experiment, Swiss mice were fed a balanced or high-fat diet and supplemented with saline, soybean oil, olive oil, or papaya seed oil.

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Article Synopsis
  • Buriti pulp oil contains beneficial bioactive substances and lipids that may help protect against cardiovascular and inflammatory diseases.
  • In a study with 108 Swiss mice over 90 days, various combinations of buriti oil and olive oil were tested, showing stability and effective metabolic interactions without affecting food intake or weight gain.
  • The strongest cardioprotective effect was seen in the group combining buriti oil and extra virgin olive oil, suggesting that this combination could be a valuable dietary supplement for people.
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The fruit and leaves of DC., locally known as , are rich in antioxidant glycosylated quercetin derivatives and phenolic compounds that have beneficial effects on diabetes mellitus, hypertension and general inflammation. We conducted a literature search to investigate the nutraceutical potentials of these phenolic compounds for treating obesity, diabetes mellitus and intestinal inflammatory disease.

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During pregnancy, women undergo metabolic and physiological changes, and their needs are higher, to maintain growth and development of the fetus. If the nutritional status of the expectant mother is not satisfactory, some maternal and neonatal complications can occur. In the second and third trimester of pregnancy, there is a reserve of nutrients in the fetus that can be utilized after birth; thereby, children present an accelerated growth in the first years of life, which is a proven response to the available nutrition pattern.

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is a genus of Clusiaceae, distributed throughout tropical Asia, Africa, New Caledonia, Polynesia, and Brazil. plants contain a broad range of biologically active metabolites which, in the last few decades, have received considerable attention due to the chemical compositions of their extracts, with compounds which have been shown to have beneficial effects in several diseases. Our work had the objective of reviewing the benefits of five species (, , , , and ).

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Olive oil is one of the main ingredients in the Mediterranean diet, being an important ally in disease prevention. Its nutritional composition is comprised of mainly monounsaturated fatty acids, with oleic being the major acid, plus minor components which act as effective antioxidants, such as hydroxytyrosol. Studies have shown that the consumption of olive oil, as well as its isolated components or in synergism, can be a primary and secondary protective factor against the development of cardiovascular diseases since it reduces the concentrations of low-density lipoproteins and increases the concentration of high-density lipoproteins.

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L. is a well-known fruit worldwide, and its highest production occurs in tropical and subtropical regions. The pulp contains vitamins A, C, and E, B complex vitamins, such as pantothenic acid and folate, and minerals, such as magnesium and potassium, as well as food fibers.

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Linn, commonly known as graviola, is one of the most popular plants used in Brazil for weight loss. The aim of this study is to evaluate the therapeutic effects of three different doses (50 mg/kg, 100 mg/kg, and 150 mg/kg) of aqueous graviola leaf extract (AGE) supplemented by oral gavage, on obese C57BL/6 mice. Food intake, body weight, an oral glucose tolerance test (OGTT), an insulin sensitivity test, quantification of adipose tissue cytokines, weight of fat pads, and serum biochemical and histological analyses of the liver, pancreas, and epididymal adipose tissue were measured.

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