Publications by authors named "Lidiane V de Castro-Hoshino"

Unlabelled: The use of foods to color other foods () should be considered in food production. In this study, freeze-dried canistel ( (Kunth) Baehni) pulp underwent a photostability test. A blue LED light with a maximum intensity of 420 nm was utilized to induce photodegradation of the pulp.

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  • Onychomycosis, a common fungal nail infection, necessitates new antifungal treatments due to existing resistance and treatment limitations.
  • This study developed antifungal nail lacquers using oregano essential oil (OEO), rosemary essential oil (REO), and biogenic silver nanoparticles (bioAgNPs), which showed promising antifungal activity and effective nail permeation.
  • Results indicated that these formulations not only reduced fungal hyphae and spores in treated nails but also maintained stability, optimal pH, and quick drying times, marking a significant advancement in treating onychomycosis with natural ingredients and nanotechnology.
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Objectives: to evaluate the quality and stability of adhesive interfaces established by self-etching adhesives on caries-affected primary dentin (CAD) treated with glutaraldehyde (GA) or silver diamine fluoride (SDF).

Methods: 42 primary molars were exposed to a microbiological caries-inducing protocol and divided into 6 groups according to the adhesive system (Clearfil SE - CL or FL Bond II - FL) and pretreatment (water, GA or SDF) applied on CAD. One tooth from each group was analyzed for surface modification using infrared spectroscopy.

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Erythrosine displays potential photodynamic activity against microorganisms and unhealthy cells. However, erythrosine has high hydrophilicity, negatively impacting on permeation through biological membranes. Combining biological macromolecules and thermoresponsive polymers may overcome these erythrosine-related issues, enhancing retention of topically applied drugs.

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  • * Results showed that thicker ceramics decreased the DC for both resin cements, while only affecting the BS of the light-cured cement in specific cases.
  • * More translucent ceramics generally provided higher DC values compared to less translucent ones, and the dual-cured cement outperformed the light-cured cement in both analyses.
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The environment can modify the physiology and body protective function of the skin. Propolis (PRP) and curcumin (CUR) possess important antioxidant and antimicrobial properties, and they can be administered in a combined way and using photodynamic therapy (PDT). Emulgels can control drug release due to the physicochemical properties of the gel and the emulsion.

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Species of the genus represent the third most common cause of onychomycosis, the most frequent and difficult to treat nail infection. Onychomycosis has been attributed to fungi organized in biofilm and some natural products have proved promising for its treatment. This study aimed to evaluate the antibiofilm activity of propolis extract (PE) and its by-product (WPE) on 7-day preformed biofilms produced by in polystyrene microplates, as well as in an ex vivo model on human nail fragments.

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Some studies have shown that freshwater ecosystems are polluted in a similar proportion to marine ecosystems; however, there are many gaps to be filled in this topic. Here, we investigated whether plastics were consumed by carnivore fishes in a Neotropical floodplain and whether it was connected to seasonality (dry and wet seasons). We also evaluated the association between each type of plastic and the fish species.

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Fungal biofilms have been involved in the pathogenesis of onychomycosis, but the aspects contributing to this association need to be enlightened. This study aimed to investigate the ability of three different fungi to form biofilm on the nail. All evaluated fungi were able to grow on the nails, using them as the only nutritional source and formed a structure strongly suggestive of biofilms.

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Objectives: This study aims to evaluate the opalescence (OP) and color stability of composite resins over a period of 180 days and to compare composite resins' OP with enamel's OP.

Materials And Methods: Twenty human enamel specimens (5.0 × 0.

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  • Fusarium spp., particularly F. oxysporum, is implicated in onychomycosis (nail infections), but its infection process and interactions with human nails are not well understood.
  • This study used human nail models to investigate how F. oxysporum produces biofilms and infects nails, employing various techniques like scanning electron microscopy and histopathology.
  • Results showed that F. oxysporum can thrive on healthy nails, establish a biofilm, and potentially lead to nail infections, contributing to the understanding of its pathogenicity.
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Objective: To evaluate the early stages of the setting process of chemically activated restorative glass-ionomer cements (GICs).

Material And Methods: Five GICs were evaluated ( = 5): Equia Forte (GC), Equia Forte HT (GC), Ketac Universal (3M ESPE), Maxxion R (FGM) and Riva Self Cure (SDI) by Thermography, Fourier Transform Infrared Attenuated Total Reflectance Spectroscopy (FTIR-ATR) and Gillmore needle indentation mechanical testing. The FTIR-ATR spectra showed the formation of metal carboxylates within the cements and enabled the stabilization time (ST) to be determined and the thermographic camera measured the temperature field images in the sample.

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Phthalocyanine aluminum chloride (Pc) is a clinically viable photosensitizer (PS) to treat skin lesions worsened by microbial infections. However, this molecule presents a high self-aggregation tendency in the biological fluid, which is an direct administration obstacle. This study proposed the use of bioadhesive and thermoresponsive hydrogels comprising triblock-type Pluronic F127 and Carbopol 934P (FCarb) as drug delivery platforms of Pc (FCarbPc)-targeting topical administration.

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  • Researchers tested a hydroalcoholic extract of L. pericarps (ETHOSS) as a potential topical antifungal treatment for onychomycosis, producing it by extracting crushed fruits in ethanol.
  • The extract demonstrated significant antifungal activity against various dermatophyte fungi, with minimum fungicide concentrations between 195.31 and 781.25 μg/mL, while showing low toxicity to human cells.
  • ETHOSS was effective in permeating healthy human nails within an hour and stayed effective for at least 24 hours, indicating its strong potential for treating fungal nail infections.
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Topical administration can enable a more efficient therapy based on the improved bioavailability and patient compliance. Wounds and infections can lead to modifications of skin physiology and body protective function. Propolis (PRP) is utilized for skin protection and treatment.

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Mucoadhesive nanostructured systems comprising poloxamer 407 and Carbopol 974P have already demonstrated good mucoadhesion, as well as improved mechanical and rheological properties. Curcumin displays excellent biological activity, mainly in oral squamous cancer; however, its physicochemical characteristics hinder its application. Therefore, the aim of this study was to develop nanostructured formulations containing curcumin for oral cancer therapy.

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Aim: To evaluate and characterize the etiopathogenesis of the fusarial onychomycosis in an ex vivo study through fragments of sterile human nail, without the addition of any nutritional source.

Materials & Methods: The infection and invasion of Fusarium oxysporum in the nail were evaluated by scanning electron microscopy (SEM), CFU, matrix, histopathology and Fourier Transform Infrared Spectrometer coupled to an equipment with diamond accessory (FTIR-ATR).

Results: F.

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Photodynamic therapy (PDT) is a therapeutic modality that has shown effectiveness in the inactivation of cancer cell lines and microorganisms. Treatment consists of activating the photosensitizer (PS) upon light irradiation of adequate wavelength. After reaching the excited state, the PS can handle the intersystem conversion through energy transfer to the molecular oxygen, generating reactive oxygen species.

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Onychomycosis is a chronic fungal infection of nails, commonly caused by dermatophyte fungi, primarily species of . Because of the limited drug arsenal available to treat general fungal infections and the frequent failure of onychomycosis treatment, the search for new therapeutic sources is essential, and topical treatment with natural products for onychomycosis has been encouraged. Propolis, an adhesive resinous compound produced by honeybees (), has shown multiple biological properties including significant antifungal and anti-biofilm activities .

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Background: Photodynamic therapy (PDT) may have topical indications. In those cases it is important for a topical photosensitizer to penetrate into the tissue to which it has been applied. This study aimed to compare the penetration of two different concentrations of erythrosine into intact and in vitro decayed dentin samples.

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