Publications by authors named "Lidia K Al-Halaseh"

Background: The investigations of snail slime and its possible biological activities have been performed recently.

Aim: This study aimed to evaluate the properties of Helix aspersa snail slime (HAS), and carotenoids-fortified slime (HASC).

Methods: Snails were fed with carrots for 10 days.

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Nanoliposomes (NLs) are ideal carriers for delivering complex molecules and phytochemical products, but ginger by-products, despite their therapeutic benefits, have poor bioavailability due to their low water solubility and stability. Crude ginger extracts (CGEs) and 6-gingerol were individually encapsulated within NLs for in vitro activity assessment. In vitro evaluation of anti-proliferative and anti-inflammatory properties of encapsulated 6-gingerol and CGE was performed on healthy human periodontal ligament (PDL) fibroblasts and MDA-MB-231 breast cancer cells.

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Article Synopsis
  • Cancer is a leading global health issue, and this research focuses on using natural compounds like gallic acid and quercetin within nanoliposomes to explore their effectiveness against various cancer cell lines and bacteria.* -
  • The study detailed the synthesis of these nanocarriers using the thin-film hydration method, with their properties assessed through techniques like Zetasizer and scanning electron microscopy.* -
  • Results indicated that the co-loaded formulation had improved drug loading capacity and cytotoxic effects against lung and breast cancer cells, while the individual nano-quercetin showed lower toxicity levels compared to other formulations.*
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Background: Nutrients are widely used for treating illnesses in traditional medicine. Ginger has long been used in folk medicine to treat motion sickness and other minor health disorders. Chronic non-healing wounds might elicit an inflammation response and cancerous mutation.

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Cosmetics, cosmeceuticals, and variable healthcare products used parabens, among other excipients, for their preservative and antimicrobial activities. Paraben derivatives exhibit distinguished physiochemical properties that enable them to be compatible with the formulation of cosmetic agents in different dosage forms. In addition to their potency and efficacy, parabens are economically efficient as they have low-manufacturing costs.

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Background: The qualified and paradigm jump in the formulation and production of cosmeceuticals refer in some way to the great revolution in nanotechnology. Nowadays, the industry of nano-formulated cosmeceuticals plays a significant and essential role in the evolution and growth of the pharmaceutical industries. This review manuscript focuses on the use of nanocarriers in delivering the cosmetic agents into the target area such as skin, hair, and nails.

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