Neurodevelopmental outcome of patients with congenital gastrointestinal malformations: a systematic review and meta-analysis.

Aim: Children with congenital gastrointestinal malformations may be at risk of neurodevelopmental impairment due to challenges to the developing brain, including perioperative haemodynamic changes, exposure to anaesthetics and postoperative inflammatory influences. This study aggregates existing evidence on neurodevelopmental outcome in these patients using meta-analysis.

Method: PubMed, Embase and Web of Science were searched for peer-reviewed articles published until October 2019.