The Role of Implant Coronal Surface Properties on Early Adhesion of Streptococcus Oralis-An In Vitro Comparative Study.

Dental implant coronal surfaces designed with the primary goal of maintaining crestal bone levels may also promote bacterial adhesion, leading to soft tissue inflammation and peri-implant bone loss. Achieving an optimal surface roughness that minimizes bacterial adhesion while preserving crestal bone is crucial. It is hypothesized that a specific threshold surface roughness value may exist below which, and above which, initial bacterial adhesion does not statistically change.

Accuracy of the Apple Watch Series 9 for Measures of Energy Expenditure and Heart Rate at Rest and During Exercise: Impact of Skin Pigmentation.

Background: The Apple Watch provides promising health data that could aid in increasing exercise adherence; regular exercise can help individuals manage and prevent diseases such as obesity and cardiovascular disease. However, the impact of skin pigmentation on the accuracy of the Apple Watch Series 9 for measures of energy expenditure (EE) and heart rate (HR) is unknown.

Purpose: The purpose of this study was to determine the accuracy of the Apple Watch Series 9 on various skin pigmentations for measures of EE and HR.

A review of portal vein embolization prior to hepatic resection.

Primary and metastatic liver cancers are increasing in incidence, and the approaches with the longest survival are resection and transplantation. Posthepatectomy liver failure (PHLF) is the leading cause of mortality following liver resection. PHLF is largely due to liver insufficiency due to the insufficient size of the future liver remnant (FLR).

Spectrum of Imaging Findings and Complications After Hepatic Transarterial Chemoembolization for Liver Tumors.

This study reviews the spectrum of imaging findings and complications after transarterial chemoembolization (TACE) for the treatment of primary liver tumors (hepatocellular carcinoma, cholangiocarcinoma) and liver metastases. The review encompasses a spectrum of imaging criteria for assessing treatment response, including the modified Response Evaluation Criteria in Solid Tumors guidelines, tumor enhancement, and apparent diffusion coefficient alterations.We discuss the expected posttreatment changes and imaging responses to TACE, describing favorable and poor responses.

Percutaneous mesocaval shunt creation for portal thrombosis in a patient with a JAK2V617F mutation.

Myeloproliferative neoplasms (MPN) are the most common cause of noncirrhotic, nontumoral portal vein thrombosis (PVT). Over 90 % of MPN patients with PVT carry the JAK2V617F mutation. Compared to other etiologies of PVT, patients with JAK2V617F MPNs are at increased risk of developing significant portal hypertension.

Umbilical Cord Stem Cell Lysate: A New Biologic Injectate for the Putative Treatment of Acute Temporomandibular Joint Inflammation.

Objective: To compare in vivo, the acute anti-inflammatory effects of a lysate derived from human umbilical perivascular mesenchymal cells with the cells themselves in both an established hind-paw model of carrageenan-induced inflammation and also in the inflamed temporomandibular joint.

Study Design: Human umbilical cord perivascular cells were harvested and cultured in xeno- and serum-free conditions to P3. In addition, P3 cells were used to prepare a proprietary 0.

Impact of the COVID-19 Pandemic on Liver Cancer Staging at a Multidisciplinary Liver Cancer Clinic.

Unlabelled: To compare liver cancer resectability rates before and during the COVID-19 pandemic.

Background: Liver cancers usually present with nonspecific symptoms or are diagnosed through screening programs for at-risk patients, and early detection can improve patient outcomes. In 2020, the COVID-19 pandemic upended medical care across all specialties, but whether the pandemic was associated with delays in liver cancer diagnosis is not known.

Intraarterial Therapies for the Management of Hepatocellular Carcinoma.

Image-guided locoregional therapies play a crucial role in the management of patients with hepatocellular carcinoma (HCC). Transarterial therapies consist of a group of catheter-based treatments where embolic agents are delivered directly into the tumor via their supplying arteries. Some of the transarterial therapies available include bland embolization (TAE), transarterial chemoembolization (TACE), drug-eluting beads-transarterial chemoembolization (DEB-TACE), selective internal radioembolization therapy (SIRT), and hepatic artery infusion (HAI).

Percutaneous Biliary Interventions: Clinical Indications, Comparative Effectiveness, Technical Considerations, Complications, and Outcomes.

Percutaneous biliary interventions (PBIs) are commonly performed by interventional radiologists for a variety of clinical indications including biliary infections, strictures, leaks, and postoperative complications. PBIs have high technical and clinical success rates and are relatively safe when compared with more invasive surgical techniques. Percutaneous transhepatic cholangiography and percutaneous biliary drainage play an essential role in the management of common posthepatobiliary complications including biliary strictures and leaks.

The Sigmoidal Nature of Bone Anchorage.

Purpose: The purpose of this study was to show the full evolution of bone anchorage caused by the growth of secondary stability and to determine which empirical model would provide the best quantitative description of this growth.

Materials And Methods: The retention and anchorage of machined (M), grit-blasted and dual acid etched (BAE), and BAE implants with discrete crystals of calcium phosphate (+DCD) were evaluated with both ex vivo and in vivo methods. Ex vivo evaluation of implant retention was tested by measuring the force required to pull implants out of blood-filled osteotomies formed in bovine bone for up to 1 hour.

Incidence and Contemporary Management of Delayed Bleeding Following Pancreaticoduodenectomy.

Background: Delayed bleeding after pancreaticoduodenectomy (PD) is a life-threatening complication. However, the optimal management remains unclear. We summarize our experience of the management of delayed bleeding after PD and define the outcomes associated with different types of management.

Minimally invasive treatment of abdominal lymphocele: A review of contemporary options and how to approach them.

Lymphoceles are lymphatic fluid collections resulting from lymphatic vessel disruption after surgery or trauma. They are most often described following retroperitoneal surgeries such as cystectomies, prostatectomies, renal transplants, and gynecologic surgeries. Most lymphoceles are asymptomatic and resolve spontaneously without treatment.

Adequacy of samples obtained via percutaneous core-needle rebiopsy for EGFR T790M molecular analysis in patients with non-small cell lung cancer following acquired resistance to first-line therapy: A systematic review and meta-analysis.

Micro Abstract: Rebiopsies characterizing resistance mutations in patients with non-small cell lung cancer (NSCLC) can guide personalized medicine and improve overall survival rates. In this systematic review, we examine the suitability of percutaneous core-needle biopsy (PT-CNB) to obtain adequate samples for molecular characterization of the acquired resistance mutation T790M. This review provides evidence that PT-CNB can obtain samples with high adequacy, with a mutation detection rate that is in accordance with prior literature.

Development, Practice Patterns, and Early Clinical Outcomes of a Multidisciplinary Liver Cancer Clinic.

Multidisciplinary care has been associated with improved survival in patients with primary liver cancers. We report the practice patterns and real world clinical outcomes for patients presenting to the Johns Hopkins Hospital (JHH) multidisciplinary liver clinic (MDLC). We analyzed hepatocellular carcinoma (HCC, n = 100) and biliary tract cancer (BTC, n = 76) patients evaluated at the JHH MDLC in 2019.

Characteristics and Outcomes of Percutaneous Biliary Interventions in the United States.

Objective: To explore baseline characteristics, comorbidities, and clinical diagnoses in the prediction of outcomes for inpatient percutaneous biliary interventions in the United States.

Methods: Hospitalizations for percutaneous transhepatic cholangiography and percutaneous biliary drainage were studied using the National Inpatient Sample 2012 to 2015. Associations between baseline characteristics, comorbidities, clinical diagnoses, and outcomes were analyzed using multivariable regression modeling.

The influence of implant design on the kinetics of osseointegration and bone anchorage homeostasis.

Titanium implants have shown considerable success in terms of achieving quick and long-lasting stability in bone through the process of osseointegration. Further work aims to improve implant success rates by modifying implant design on the nano-, micro-, and macro- scales with the goal of achieving higher levels of bone anchorage more quickly. However, the most frequently used methods of analysis do not investigate bone anchorage as a whole but as a series of discrete points, potentially missing relevant insight which could inform the effects of topography on these 3 scale ranges.