Effect of integrated manual and verbal cueing on functional transfers in chronic stroke survivors: a randomized controlled study.

Purpose: The profession of physical therapy has historically relied on manual facilitation to improve motor control strategies and performance in persons rehabilitating from a stroke, yet there is insufficient evidence to support its use during functional task training. The purpose of this study was to determine the effects of integrated cueing (verbal and manual) and verbal cueing approaches during sit-to-stand training on midline alignment & muscle activation in chronic stroke survivors.

Methods: Twenty-one chronic right-brained stroke survivors with hemiplegia were randomly assigned to the Integrated Cueing or Verbal Only group and outcome measures were recorded using an 18-Camera Motion Capture System, force plates, and surface electromyography (EMG).

Risk factors for in-hospital mortality among patients hospitalized with COVID-19 and end-stage kidney disease.

Aims: The mortality rate for -COVID-19 infection varies significantly depending on age and comorbidities but remains high in hospitalized patients overall. Several retrospective studies have identified patients with end-stage kidney disease (ESKD) to be at increased risk. The objective of this study was to study in-hospital outcomes of ESKD patients at an academic medical center and identify characteristics that place them at a higher risk for in-hospital mortality.

Multi-species synbiotic supplementation increased fecal short chain fatty acids and anti-inflammatory cytokine interleukin-10 in adult men with dyslipidemia; A randomized, double-blind, clinical trial.

Background: Mounting evidence revealed that an imbalance of Gut Microbiota (GM) leads to metabolic disorders. Synbiotics through regulation of GM composition can be an effective intervention in the management of metabolic diseases. This study aimed to investigate the effects of multi-species synbiotic supplementation on serum interleukin10 (IL-10) and fecal Short Chain Fatty Acids (SCFAs) in patients with dyslipidemia.

The feigned annoyance and frustration test to activate the sympathoadrenal medullary system.

When perceived as threatening, social interactions have been shown to trigger the sympathoadrenal medullary system as well as the hypothalamic-pituitary-adrenal axis resulting in a physiologic stress response. The allostatic load placed on human health and physiology in the context of acute and chronic stress can have profound health consequences. The purpose of this study was to develop a protocol for a lab-based stress stimulus using social-evaluative threat.

External handheld loads affect scapular elevation and upward rotation during shoulder elevation tasks.

Altered scapular kinematics is associated with shoulder pain. Resistance exercise is a common treatment; however, the effects of lifting an external load on scapular kinematics is limited. Understanding whether an external handheld load affects scapular kinematics in a healthy population can provide normal values utilized for comparison to individuals with shoulder pain.

High-Intensity interval training reduces transcriptomic age: A randomized controlled trial.

While the relationship between exercise and life span is well-documented, little is known about the effects of specific exercise protocols on modern measures of biological age. Transcriptomic age (TA) predictors provide an opportunity to test the effects of high-intensity interval training (HIIT) on biological age utilizing whole-genome expression data. A single-site, single-blinded, randomized controlled clinical trial design was utilized.

Treating peripheral neuropathy in individuals with type 2 diabetes mellitus with intraneural facilitation: a single blind randomized control trial.

Objective: To evaluate the effectiveness of intraneural facilitation (INF) for the treatment of diabetic peripheral neuropathy (DPN).

Methods: This single-blind, randomized clinical trial enrolled patients with type 2 diabetes mellitus and moderate-to-severe DPN symptoms below the ankle. Patients were randomly assigned to receive INF or sham treatment.

Prospective, Randomized, Double-Blinded, Sham-Controlled Pilot Study of Intraneural Facilitation as a Treatment for Carpal Tunnel Syndrome.

Objective: To perform a pilot study to assess the efficacy of intraneural facilitation, a novel manual technique, in the treatment of carpal tunnel syndrome (CTS).

Design: Patients with clinical and electrodiagnostic evidence of CTS were randomized into intraneural facilitation or sham groups.

Setting: Electrodiagnostic laboratory in a university medical center.

The relationship between kinesiophobia and biomechanics in anterior cruciate ligament reconstructed females.

Objective: Kinesiophobia has been associated with deleterious biomechanical alterations during dual-limb landing tasks in anterior cruciate ligament (ACL) reconstructed females, however, no research has yet investigated single-limb tasks related to ACL injury. The aim of this investigation was to examine the relationship between kinesiophobia and biomechanics during a series of dual and single-limb functional tasks associated with ACL injury risk.

Design: Cross-sectional study.

Integration of Spirituality and Whole Person Care into Doctor of Physical Therapy Curricula: A Mixed Methods Study.

A novel whole person care course, emphasizing spirituality in healthcare, was developed for first-year Doctor of Physical Therapy students with interprofessional collaboration between faculty members of the School of Religion and the School of Allied Health physical therapy program. The course was designed to support compassionate, person-centered care, inclusive of spirituality, using the biopsychosocialspiritual framework. The purpose of this study was to explore physical therapy students' perceptions of spiritual care, identify student comfort level in addressing patient spiritual issues, and assess change in perception of the value of addressing spirituality with completion of a required whole person care course.

The influence of hip flexion mobility and lumbar spine extensor strength on lumbar spine flexion during a squat lift.

Study Design: Cross-sectional; Controlled laboratory study.

Objective: To examine the associations among available hip flexion motion, lumbar extensor strength and peak lumbar flexion during a squat lift task.

Summary Of Background Data: Lumbar spine flexion during lifting can result in increased strain on spinal structures.

The influence of hip extensor and lumbar spine extensor strength on lumbar spine loading during a squat lift.

Weakness of the hip extensors and lumbar spine extensors has been proposed to contribute to greater demands on the lumbar spine during lifting. The purpose of the current study was to examine the associations among strength of the hip and lumbar spine extensors, lumbar spine extensor moments and lumbar paraspinal muscle activation during a squat lift task. Twenty-seven healthy females participated.

The association between ambient fine particulate matter and incident adenocarcinoma subtype of lung cancer.

Background: Adenocarcinoma (AC) is the most common lung cancer among non-smokers, but few studies have assessed the effect of PM on AC among never smokers. The purpose of this study was to assess the association between ambient PM and incident lung AC in the Adventist Health and Smog Study-2 (AHSMOG-2), a cohort of 80,044 non-smokers (81% never smokers) followed for 7.5 years (597,177 person-years) (2002-2011).

The Association between Ambient Fine Particulate Air Pollution and Lung Cancer Incidence: Results from the AHSMOG-2 Study.

Background: There is a positive association between ambient fine particulate matter ≤ 2.5 μm in aerodynamic diameter (PM) and incidence and mortality of lung cancer (LC), but few studies have assessed the relationship between ambient PM and LC among never smokers.

Objectives: We assessed the association between PM and risk of LC using the Adventist Health and Smog Study-2 (AHSMOG-2), a cohort of health conscious nonsmokers where 81% have never smoked.