The Prognostic Significance of the TEAD4 in Hepatocellular Carcinoma.

Background: Abnormal expression of genes causes tumorigenesis, tumor progression, and poor prognosis in hepatocellular carcinoma (HCC). Therefore, the aims of this study were to explore the transcription enhancer domain factor 4 (TEAD4) in patients with liver cancer and its relationship with prognosis.

Methods: HTSeq-FPKM data and corresponding clinical data of HCC patients were obtained from The Cancer Genome Atlas (TCGA).

Preparation of Boron/Sulfur-Codoped Porous Carbon Derived from Biological Wastes and Its Application in a Supercapacitor.

Abundant biomass resources are a good choice for preparing electrode materials for supercapacitors, but developing a versatile and simple synthetic method to convert them into electrode materials remains a challenge. In the present research, our team reports a promising strategy and cost-efficient method to fabricate boron/sulfur-codoped porous carbon from biomass sources, mainly utilizing four biomass materials. Detailed material characterization showed that the samples produced by this approach possess rich B and S doping.

Preparation and Self-Cleaning Performance of Carbon-Based Superhydrophobic Coatings Based on Non-Fluorine and Non-Toxic Corn Straw.

Recently, superhydrophobic surfaces with self-cleaning ability have attracted broad research interest due to their huge potential in daily lives and industrial applications, but the use of fluorinate, toxic organic compounds, and expensive feedstocks make superhydrophobic materials a great challenge in practical application. In this study, we present a facile dip-coating strategy to prepare superhydrophobic coatings with self-cleaning properties based on a non-fluorine and non-toxic system by using eco-friendly corn straw as raw material. During this process, aromatic carbon particles with rough hierarchical structures were prepared firstly via a simple fast pyrolysis process, followed by modification with polydimethylsiloxane (PDMS) in absolute ethanol solvent to decrease the surface free energy.

CXCL5, the upregulated chemokine in patients with uterine cervix cancer, in vivo and in vitro contributes to oncogenic potential of Hela uterine cervix cancer cells.

CXCL5 is showed a surprisingly elevated profile and implicated in tumorigenesis in several tumors. However, the expression and function of CXCL5 in uterine cervix cancer (UCC) remain largely unknown. The current study aimed to elucidate the expression pattern of CXCL5 in human UCC tissues and Hela cervix cancer cell, as well as its functions in Hela cells.

Chemokine CXCL3 mediates prostate cancer cells proliferation, migration and gene expression changes in an autocrine/paracrine fashion.

Introduction: We have previously indicated that CXCL3 was upregulated in the tissues of prostate cancer, and exogenous administration of CXCL3 played a predominant role in the tumorigenicity of prostate cancer cells. In the present study, we further explored the role and the underlying mechanism of CXCL3 overexpression in the oncogenic potential of prostate cancer in an autocrine/paracrine fashion.

Methods: CXCL3-overexpressing prostate cancer cell line PC-3 and immortalized prostate stromal cell line WPMY-1 were established by gene transfection.

IL-8 is upregulated in cervical cancer tissues and is associated with the proliferation and migration of HeLa cervical cancer cells.

Interleukin-8 (IL-8) serves an important function in chronic inflammation and cancer development; however, the underlying molecular mechanism(s) of IL-8 in uterine cervical cancer remains unclear. The present study investigated whether IL-8 and its receptors [IL-8 receptor (IL-8R)A and IL-8RB] contributed to the proliferative and migratory abilities of HeLa cervical cancer cells, and also investigated the potential underlying molecular mechanisms. Results demonstrated that IL-8 and its receptors were detected in HeLa cells, and levels of IL-8RA were significantly increased compared with those of IL-8RB.

Overexpression of CXCL3 can enhance the oncogenic potential of prostate cancer.

Purpose: CXCL3 and its receptor CXCR2 were considered to play particularly important roles in the progression of malignancies. However, the investigations about CXCL3/CXCR2 axis in prostate cancer have been poorly involved. Herein we firstly reported our studies on the expression and biological roles of CXCL3 and CXCR2 in prostate cancer.