Diagnostic challenges of diffuse leptomeningeal glioneuronal tumor in an adult female: illustrative case.

Background: Diffuse leptomeningeal glioneuronal tumor (DLGNT) is a rare central nervous system tumor, especially in adult females. Typically, it presents with leptomeningeal enhancements in the basal cisterns and spinal cord. However, varied radiological and pathological features can complicate the diagnosis, as the present case illustrates.

Chinese Doctoral Students Involved in Interdisciplinary Learning Score Higher on Scientific Creativity: The Roles of Teamwork Skills and Collaborative Behaviors.

Despite the growing recognition of the value of interdisciplinary learning in doctoral education, there is still a gap in the literature supporting the relationship between it and doctoral students' scientific creativity in China. Based on a questionnaire survey of 457 doctoral students from the humanities and social sciences on the Chinese Mainland, this study adopted structural equation modeling to examine the relationships among interdisciplinary learning, teamwork skills, collaborative behaviors, and scientific creativity. The results indicated that there was a weak positive correlation between interdisciplinary learning and the scientific creativity of doctoral students.

Multi-functional, conformal systems with ultrathin crystalline-silicon-based bioelectronics for characterization of intraocular pressure and ocular surface temperature.

Technologies that established in vivo evaluations of soft-tissue biomechanics and temperature are essential to biological research and clinical diagnostics, particularly for a wide range of eye-related diseases such as glaucoma. Of importance are advanced bioelectronic devices for high-precise monitoring of intraocular pressure (IOP) and various ocular temperatures, as clinically proven uses for glaucoma diagnosis. Existing characterization methods are temporary, single point, and lack microscale resolution, failing to measure continuous IOP fluctuation across the long-term period.

Exploring the effects of an online learning platform in stage III cardiac rehabilitation for individuals with coronary heart disease: Randomized controlled study.

The objective of this study is to assess the influence of blended education methodologies, utilizing an online education platform, among stage III cardiac rehabilitation (CR) patients diagnosed with coronary heart disease (CHD). Between June and August 2021, a cohort of 90 patients diagnosed with CHD, previously discharged from a second-class hospital 1 year earlier, were randomly allocated into 2 groups: the experimental and control groups, with each comprising 45 patients. Patients in the control group received out-of-hospital CR education via WeChat, while those in the experimental group received blended CR education utilizing an online education platform.

Needs and Constraints for Cardiac Rehabilitation Among Patients with Coronary Heart Disease Within a Community-Based Setting: A Study Based on Focus Group Interviews.

Objective: This study aimed to explore the needs and constraints to cardiac rehabilitation (CR) among patients diagnosed with coronary heart disease (CHD) in a community-based setting, and thereby facilitating the implementation of effective CR programs for this population.

Methods: Focus group interviews were used as the primary research methodology. A total of 11 community-dwelling individuals diagnosed with CHD were selected from a community hospital to participate in in-depth interviews, aiming to discern and analyze their requirements and constraints experienced concerning medical resources and healthcare agency.

Association Between the Serum α-Klotho Level and Insulin Resistance in Adults: NHANES 2007-2016.

Objective: This study aimed to investigate the relationship between serum α-Klotho levels and insulin resistance (IR), a precursor to type 2 diabetes.

Methods: The study analyzed data from 4,758 adult participants in the National Health and Nutrition Examination Survey (NHANES) spanning from 2007 to 2016. The relationship between α-Klotho concentration and IR was assessed using the Homeostatic Model Assessment of Insulin Resistance (HOMA-IR) and odds ratios (OR) derived from logistic regression models.

Illumina and Nanopore sequencing in culture-negative samples from suspected lower respiratory tract infection patients.

Objective: To evaluate the diagnostic value of metagenomic sequencing technology based on Illumina and Nanopore sequencing platforms for patients with suspected lower respiratory tract infection whose pathogen could not be identified by conventional microbiological tests.

Methods: Patients admitted to the Respiratory and Critical Care Medicine in Shanghai Ruijin Hospital were retrospectively studied from August 2021 to March 2022. Alveolar lavage or sputum was retained in patients with clinically suspected lower respiratory tract infection who were negative in conventional tests.

Reversible Transformation and Distribution Determination of Diverse Pt Single-Atom Species.

In single-atom catalysts (SACs), the complexity of the support anchoring sites creates a vast diversity of single-atom species with varied coordination environments. To date, the quantitative distribution of these diverse single-atom species in a given SAC has remained elusive. Recently, CeO-supported metal SACs have been extensively studied by modulating their local environments via numerous synthetic strategies.

The bidirectional association of C-peptide with cardiovascular risk in nondiabetic adults and patients with newly diagnosed type 2 diabetes mellitus: a retrospective cohort study.

Background: Recent literature reported the biological role of C-peptide, but this role is still controversial and unclear. The primary aim of this study was to investigate associations between C-peptide and cardiovascular biomarkers as well as events.

Methods: A total of 55636 participants who had a health examination from 2017 to 2021 were included.

Screening of universal DNA barcodes for identifying grass species of Gramineae.

There is currently international interest in applying DNA barcoding as a tool for plant species discrimination and identification. In this study, we evaluated the utility of four candidate plant DNA barcoding regions [, , -, and internal transcribed spacer ()] in seven genera of Gramineae including , , , , , , and . Fourteen accessions were analyzed, and and showed the highest species, subspecies, and variety discriminatory power, each resolving 11 accessions.

A High-Quality Genome Assembly of .

Sweet sorghum () is a high-quality bio-energy crop that also serves as food for humans and animals. However, there is little information on the genomic characteristics of . In this study, we presented a high-quality assembly of with PacBio long reads, Illumina short reads, high-throughput chromosome capture technology (Hi-C) sequencing data, gene annotation, and a comparative genome analysis.

A de novo assembled high-quality chromosome-scale Trifolium pratense genome and fine-scale phylogenetic analysis.

Background: Red clover (Trifolium pratense L.) is a diploid perennial temperate legume with 14 chromosomes (2n = 14) native to Europe and West Asia, with high nutritional and economic value. It is a very important forage grass and is widely grown in marine climates, such as the United States and Sweden.

Genomic characterization and expression analysis of transcription factors in and .

The plant-specific transcription factor plays important roles in plant development and environment adaptation. and , the C4 model plants, can grow on drought or arid soils. However, there is no systematic information about the genomic dissection and the expression of genes.

High-quality chromosome-scale de novo assembly of the Paspalum notatum 'Flugge' genome.

Background: Paspalum notatum 'Flugge' is a diploid with 20 chromosomes (2n = 20) multi-purpose subtropical herb native to South America and has a high ecological significance. It is currently widely planted in tropical and subtropical regions. Despite the gene pool of P.

Change of vitamin D status and all-cause mortality among Chinese older adults: a population-based cohort study.

Background: The association of vitamin D with all-cause mortality remains controversial and longitudinal evidence exploring the potential effects of change in vitamin D status is limited in the oldest old (aged ≥ 80 years old). We aimed to study the relationship between vitamin D change and all-cause mortality among older Chinese adults including the oldest old.

Methods: The data of Chinese Longitudinal and Health Longevity Study in 2012 and 2014 wave was used for baseline data.

Effects of a prolonged diet regimen on autophagic function in rat islets with aging.

The prevalence of type 2 diabetes increases with age-associated increased susceptibility of islet β-cells and altered dietary patterns, in part because of insufficient compensation of β-cell functional mass in the face of increasing insulin resistance. However, the underlying mechanisms have not been fully elucidated. In the present study, we investigated the effects of a long-term calorie-restricted (CR) or high-fat (HF) diet compared to a normal ad libitum diet on β-cell structure-function relationships and autophagy in the islets of 3- and 24-month-old Fischer 344 rats.

Genomic Insight into the Antimicrobial Resistance of - Six Countries, 2011-2019.

What Is Already Known On This Topic?: () is a zoonotic pathogen causing disease in humans and animals, and the emergence of its increased resistance to antimicrobial agents has become a significant challenge in many countries.

What Is Added By This Report?: Using whole genome sequencing data to accurately predict antimicrobial resistance determinants, it was found that the prevalence of antimicrobial resistance genes was higher in the pig isolates of than in the human isolates and that the prevalence of these genes varied with serotype.

What Are The Implications For Public Health Practice?: The data regarding antimicrobial resistance will help guide rational drug use in the clinic to better protect the health of humans and animals.

Integrative analysis of the metabolome and transcriptome reveal the phosphate deficiency response pathways of alfalfa.

Understanding the mechanisms underlying the responses to inorganic phosphate (Pi) deficiency in alfalfa will help enhance Pi acquisition efficiency and the sustainable use of phosphorous resources. Integrated global metabolomic and transcriptomic analyses of mid-vegetative alfalfa seedlings under 12-day Pi deficiency were conducted. Limited seedling growth were found, including 13.

hydroponics system efficiency for the cuttings of alfalfa ( L.).

The legume plant alfalfa ( L.) is a widely cultivated perennial forage due to its high protein content, palatability, and strong adaptability to diverse agro-ecological zones. Alfalfa is a self-incompatible cross-pollinated autotetraploid species with tetrasomic inheritance.

Comprehensive analysis of coding sequence architecture features and gene expression in .

Coding sequence (CDS) architecture affects gene expression levels in organisms. Codon optimization can increase the gene expression level. Therefore, understanding codon usage patterns has important implications for research on genetic engineering and exogenous gene expression.

Characterization of Two New Mutations From an EMS-Mutagenic Maize Population for Lignocellulosic Biomass Utilization.

Gene mutations linked to lignin biosynthesis are responsible for the phenotypes. The mutants have a brown-reddish midrib associated with changes in lignin content and composition. Maize is caused by a mutation of the cinnamyl alcohol dehydrogenase gene .