Magnetic Barkhausen noise (MBN) is one of the most effective methods for determining the easy axis of ferromagnetic materials and for evaluating texture and residual stress in a nondestructive manner. MBN signals from multiple angles and different magnetization sections can be used to characterize magnetic anisotropy caused by various magnetization mechanisms. This paper reviews the development and application of magnetic anisotropy detection technology, and the MBN anisotropy models that take into account domain wall motion and magnetic domain rotation are analyzed thoroughly.
View Article and Find Full Text PDFNanotechnology
December 2023
While studying time fractional fluid flow problems it is typical to consider the Caputo derivative, however, these models have limitations including a singular kernel and an infinite waiting time from a random walk perspective. To help remedy this problem, this paper considers a tempered Caputo derivative, giving the system a finite waiting time. Initially, a fast approximation to a generalised tempered diffusion problem is developed using a sum of exponential approximation.
View Article and Find Full Text PDFBased on relevant literature, this study adopted entrepreneurial learning theory to construct a relationship model between entrepreneurial learning and entrepreneurial intention. In this framework, entrepreneurial learning was divided into three dimensions: entrepreneurial education learning, experiential learning, and social network learning. A questionnaire survey was conducted among 1,399 undergraduate students in Zhejiang Province to investigate how entrepreneurial learning influenced entrepreneurial intention, while considering the mediating effect of entrepreneurial self-efficacy.
View Article and Find Full Text PDFZhonghua Wei Zhong Bing Ji Jiu Yi Xue
July 2022
Objective: To analyze protein profiles in septic patients, and to find potential new targets for the diagnosis and treatment of sepsis.
Methods: A cross sectional observational study was conducted. From January to December 2019, 12 septic patients and 9 healthy volunteers were recruited in the emergency intensive care unit (EICU) of the emergency department of the Affiliated Hospital of Southwest Medical University.
Tumor deposits (TD) of colorectal cancer (CRC) in the 8 edition of TNM classification (TNM 8) were staged as N1c, but the number of TDs was ignored. The aim of this study was to analyze the association of TD with CRC and verify the rationale for TD staging in the TNM 8. A total of 517 patients with CRC, surgically treated from Aug.
View Article and Find Full Text PDFThe aim of the present study was to evaluate the efficacy and safety of imatinib mesylate in unresectable gastrointestinal stromal tumor (GIST) and to discuss its therapeutic regimen. A patient with unresectable GIST is described, and several key clinical studies are reviewed, including the clinical trials B2222 and S0033, which contain recently reported results of the long-term clinical outcome of imatinib in patients with unresectable or metastatic GIST. The recent results of the two studies demonstrate the long-term efficacy and safety of imatinib for unresectable or metastatic GIST.
View Article and Find Full Text PDFHepatolithiasis, originally as oriental cholangiohepatitis, especially prevails in Asia, but globalization and intercontinental migration have also converted the endemic disease dynamics around the world. Characterized by its high incidence of ineffective treatment and recurrence, hepatolithiasis, always, poses a therapeutic challenge to global doctors. Although the improved surgical and non-surgical techniques have evolved over the past decade, incomplete clearance and recurrence of calculi are always so common and disease-related mortality from liver failure and concurrent cholangiocarcinoma still exists in the treatment of hepatolithiasis.
View Article and Find Full Text PDFZhonghua Wei Chang Wai Ke Za Zhi
October 2015
Objective: To observe the impact of intraoperative peritoneal chemotherapy with Lobaplatin on the safety of postoperative bowel function and complications in patients with advanced colorectal cancer.
Methods: A total of 103 colorectal cancer patients undergoing surgical operations in our department between October 2013 and October 2014 were prospectively enrolled in this study and were randomly divided into peritoneal chemotherapy group(55 cases) and control group(48 cases) according to the random table. In therapy group, patients were treated with peritoneal implantation of 40 mg Lobaplatin intraoperatively and followed by intravenous chemotherapy using FOLFOX regimen with Oxaliplatin, Fluorouracil and Leucovorin.
When gene therapy is performed for the treatment of malignant tumors, gene transfer efficiency and selectivity are highly important. Polymer vehicle microspheres are a novel type of therapy, which have been developed rapidly in recent years and are able to control drug release, prolong the biological half-life of drugs, decrease side effects and achieve targeted delivery. The present study was designed to construct a polymer microsphere-encapsulated recombinant adenovirus with human tissue inhibitors of the matrix metalloproteinase-1 (TIMP-1) gene, and to discuss its characterization for the purpose of liver cancer gene therapy.
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