SrAlO:Li,Mn phosphor-in-glass film: erosion behavior and luminescence property.

At present, phosphor-in-glass is regarded as a superior encapsulation material substituting for organic materials to resolve the poor thermal stability of WLEDs. However, the serious erosion reaction between commercial red phosphor and the glass matrix restricts the development and application of red phosphor-in-glass. In this work, a novel SrAlO:Li,Mn (SAO) red phosphor-in-glass film (PiGF) with precursor glass BO-(85 - )BiO-5AlO-10CaO was prepared using a low-temperature sintering technique.

The role of the "gut microbiota-mitochondria" crosstalk in the pathogenesis of multiple sclerosis.

Multiple Sclerosis (MS) is a neurologic autoimmune disease whose exact pathophysiologic mechanisms remain to be elucidated. Recent studies have shown that the onset and progression of MS are associated with dysbiosis of the gut microbiota. Similarly, a large body of evidence suggests that mitochondrial dysfunction may also have a significant impact on the development of MS.

Theoretical calculations and photoluminescence properties of SrAlO:Mn red phosphors doped with Li.

The absence of high-efficiency oxide red phosphors restricts the development of high-performance solid-state lighting. In this work, a series of Li doped SrAlO:Mn (SAO-Li) red phosphors were prepared. Theoretical calculation results indicate that Li is inclined to occupy the gap 2 position.

A tree shrew model for steroid-associated osteonecrosis.

Osteonecrosis is a common human disease in orthopedics. It is difficult to treat, and half of patients may need artificial joint replacement, resulting in a considerable economic burden and a reduction in quality of life. Hormones are one of the major causes of osteonecrosis and high doses of corticosteroids are considered the most dangerous factor.

Effects of combined treatment with PD‑L1 Ig and CD40L mAb on immune tolerance in the CBA/J x DBA/2 mouse model.

The embryo is a natural allograft and is the only exception to immune rejection, which reflects maternal immune tolerance towards the embryo. However, pregnancy loss is primarily caused by maternal immune rejection of the embryo. The aim of the present study was to explore the effects of combined treatment of programmed death‑ligand 1 (PD‑L1) immunoglobulin (Ig) and CD40‑ligand (CD40L) monoclonal antibody (mAb) on immune tolerance in an abortion‑prone mating model.

Sitagliptin/Metformin Versus Insulin Glargine Combined With Metformin in Obese Subjects With Newly Diagnosed Type 2 Diabetes.

To compare the therapeutic effects of different regimens in Chinese obese type 2 diabetic mellitus (T2DM) patients. From October 2013 to July 2014, a total of 166 T2DM outpatients who attended the Shanghai Changhai Hospital and the Yijishan Hospital of Wannan Medical College were randomly assigned into an experimental sitagliptin/metformin combined with low caloric diet group (n = 115) and an insulin glargine combined with metformin control group (n = 51). Inclusion criteria were body mass index (BMI) ≥ 25 kg/m and diagnosed with T2DM with glycosylated hemoglobin (glycated hemoglobin A1C [HbA1c]) >9%.

TM7SF1 (GPR137B): a novel lysosome integral membrane protein.

In the previous proteomic study of human placenta, transmembrane 7 superfamily member 1 (TM7SF1) was found enriched in lysosome compartments. TM7SF1 encodes a 399-amino acid protein with a calculated molecular mass of 45 kDa. Bioinformatic analysis of its amino acid sequence showed that it is a multipass transmembrane protein containing a potential dileucine-based lysosomal targeting signal and four putative N-glycosylation sites.

catena-Poly[[tetra-aqua-cobalt(II)]-μ-2,2'-dihydroxy-5,5'-diazenediyldibenzoato].

In the title compound, [Co(C(14)H(8)N(2)O(6))(H(2)O)(4)](n), each 5,5'-diazenediylbis(2-hydroxy-benzoato) ligand acts as a dicarboxyl-ate bridge, leading to the formation of polymeric chains running in the [10] direction. The Co atom is hexa-coordinated in a distorted octa-hedral geometry by six O atoms [Co-O = 2.039 (4)-2.