Determination of sweetener specificity of horse gut-expressed sweet taste receptor T1R2-T1R3 and its significance for energy provision and hydration.

Studies carried out in several species have demonstrated that detection of low-calorie sweeteners in the lumen of the intestine, by the sweet receptor, T1R2-T1R3, initiates a signaling pathway leading to enhanced expression and activity of intestinal Na/glucose cotransporter 1, SGLT1. This results in an increased gut capacity to absorb glucose, sodium chloride and water, the basis for oral rehydration therapy. Horses express T1R2, T1R3 and downstream signaling elements in the intestinal tissue.

Listening to the "wives" of the "female husbands".

SUMMARY This article treats two of the central queer texts of eighteenth-century Britain, the autobiographical narrative of Charlotte Charke, a well-known cross-dressing actress who spent a portion of her life as a husband to another woman, and Henry Fielding's pamphlet, The Female Husband. Focusing on these texts, this study moves away from the traditional subject of such work-the female husbands themselves- and instead centers on the wives and lovers of these figures. In this way, the author offers a model of what she calls a project of imaginary coalition-building across time between contemporary femmes and the differ-ently-but still queerly-desiring feminine women in Charke's and Fielding's texts.