Clip placement after stereotactic vacuum-assisted breast biopsy.

Purpose: To assess accuracy and usefulness of placement of a localizing clip after stereotactic, vacuum-assisted breast biopsy.

Materials And Methods: Retrospective review was performed of 57 lesions that underwent placement of a localizing clip after stereotactic vacuum-assisted biopsy with an 11-gauge (n = 42) or 14-gauge (n = 15) probe. The clip was placed when images obtained after stereotactic biopsy suggested that the lesion seen at mammography was removed.

Stereotactic core biopsy of calcifications highly suggestive of malignancy.

Purpose: To assess stereotactic core biopsy for evaluation of Breast Imaging Reporting and Data System (BI-RADS) category 5 calcifications (highly suggestive of malignancy).

Materials And Methods: Retrospective review of mammograms revealed 31 women (aged 34-86 years) with BI-RADS category 5 calcifications who underwent 14-gauge stereotactic core biopsy with an automated gun. Records were reviewed to determine the frequency with which stereotactic core biopsy obviated a surgical procedure.

Mammographic findings after stereotactic 14-gauge vacuum biopsy.

Purpose: To evaluate mammographic findings after stereotactic 14-gauge vacuum biopsy.

Materials And Methods: Retrospective review was performed of results at stereotactic 14-gauge vacuum biopsy in 108 lesions in 100 women. The median number of specimens obtained per lesion was 12 (mean, 14; range, 1-50).

Analysis of cancers not diagnosed at stereotactic core breast biopsy.

Purpose: To evaluate the mammographic and histopathologic features of carcinomas not diagnosed at stereotactic core biopsy.

Materials And Methods: A retrospective review revealed 144 surgically confirmed carcinomas preoperatively sampled with stereotactic core biopsy. Diagnosis at stereotactic core biopsy was carcinoma in 116 (81%) lesions, atypical hyperplasia in 21 (15%), and benign findings discordant with those from mammography in seven (5%).

Patterns of mammographically detected calcifications after breast-conserving therapy associated with tumor recurrence.

Background: Some authors have suggested that mammographically evident calcifications that would be considered benign in other situations can be due to carcinoma in women who have undergone breast conservation. This study was undertaken to determine if the pattern of calcifications associated with recurrent tumors detected mammographically differs from that observed in carcinomas developing de novo.

Methods: Mammograms of 22 cases of local tumor recurrence were retrospectively reviewed, and calcifications associated with recurrence were characterized according to the American College of Radiology Breast Imaging Reporting and Data System (BI-RADS) classification.

Impact of core biopsy on the surgical management of impalpable breast cancer.

Objective: The purpose of this study was to compare impalpable breast carcinomas revealed by core biopsy with those revealed by surgical biopsy with respect to the frequency of performing a single surgical procedure and finding tumor at the margins of the lumpectomy specimen.

Materials And Methods: Retrospective review found 197 solitary impalpable breast carcinomas revealed by core biopsy using a 14-gauge needle (n = 90) or surgical biopsy after needle localization (n = 107). Lumpectomy was the surgical treatment in 62 (69%) of the 90 cancers revealed by core biopsy and in 74 (69%) of the 107 cancers revealed by surgical biopsy.

Mammographic features of local recurrence in women who have undergone breast-conserving therapy for ductal carcinoma in situ.

Objective: This study was undertaken to evaluate the mammographic features of local recurrence in women who have undergone breast-conserving therapy for ductal carcinoma in situ (DCIS).

Materials And Methods: Retrospective review revealed 162 women with DCIS treated with breast-conserving therapy from 1978 to 1990 for whom follow-up data were available. Subsequent to therapy, 33 (20%) patients had a pathologically proven carcinoma in the treated breast.

Overdiagnosis of medullary carcinoma: a mammographic-pathologic correlative study.

Purpose: To evaluate the mammographic features of medullary carcinoma, to determine the frequency of pathologic overdiagnosis of this neoplasm, and to assess whether mammography can distinguish true from atypical medullary carcinomas, since this distinction has important prognostic implications.

Materials And Methods: Retrospective review revealed 25 patients with an initial pathologic diagnosis of medullary carcinoma. Histopathologic slides and mammograms were reviewed.

Spiculated axillary adenopathy.

Purpose: To describe the mammographic and sonographic appearance of a pattern of spiculation of the contour of axillary lymph nodes.

Materials And Methods: Eleven cases of axillary nodes with spiculated contour were prospectively identified on routine mammograms. All cases were in women with breast cancer.

Core needle biopsy of synchronous ipsilateral breast lesions: impact on treatment.

Objective: The purpose of this study was to evaluate the role of core biopsy in the diagnosis of multiple synchronous ipsilateral breast lesions and to determine the impact of this information on patients' management.

Materials And Methods: Of 371 patients who underwent core-needle breast biopsy under stereotaxic (n = 278) or sonographic (n = 93) guidance, 20 (5%) underwent core biopsy of two mammographically separate lesions in the ipsilateral breast on the same date. Fourteen of these 20 patients subsequently underwent surgery.

Nondiagnostic stereotaxic core breast biopsy: results of rebiopsy.

Purpose: To determine the clinical implication of recommendation for repeat biopsy after large-core stereotaxic breast biopsy.

Materials And Methods: Repeat biopsy was recommended in 56 (18%; mean age, 51.0 years) of 314 consecutive women who underwent stereotaxic core biopsy.

Benign and malignant phyllodes tumors: mammographic and sonographic findings.

Purpose: To characterize imaging findings that suggest the benign or malignant histologic nature of phyllodes tumors.

Materials And Methods: Clinical and imaging findings were retrospectively reviewed in 46 women with 51 phyllodes tumors (32 benign, 19 malignant) identified at preoperative mammography. Thirty of these tumors were also evaluated with preoperative sonography.

Pseudoangiomatous stromal hyperplasia: mammographic, sonographic, and clinical patterns.

Purpose: To analyze the mammographic, ultrasonographic (US), and clinical patterns of pseudoangiomatous stromal hyperplasia (PASH).

Materials And Methods: Preoperative mammographic and US images, clinical records, and histologic assessments were reviewed in seven cases of PASH as the sole component or dominant stromal component of a clinically or mammographically defined mass lesion. In five, a PASH tumor was diagnosed at image-guided 14-gauge core-needle biopsy; in two, it was diagnosed at surgical excisional biopsy.

Recurrent carcinoma after breast conservation: diagnosis with stereotaxic core biopsy.

Purpose: To evaluate the utility of stereotaxic core biopsy (SCB) in diagnosing recurrent carcinoma after breast-conserving therapy (BCT).

Materials And Methods: Of 316 patients evaluated with SCB, 17 (5%) had nonpalpable lesions in breasts previously treated with BCT. Surgical correlation was obtained in 14 patients.

Stereotaxic core biopsy of impalpable spiculated breast masses.

Objective: The role of stereotaxic core biopsy in evaluating mammographically detected lesions that have a high probability of being malignant is still debated. This study was undertaken to assess the use of stereotaxic core biopsy in evaluating spiculated masses, by determining the frequency with which core biopsy reduced the number of surgical procedures performed in the management of these highly suspicious lesions.

Materials And Methods: Forty-three impalpable spiculated breast masses in 43 patients were sampled with stereotaxic core biopsy.

Mammography immediately after stereotaxic breast biopsy: is it necessary?

Objective: The purpose of this study was to determine whether mammography immediately after stereotaxic core breast biopsy should be performed routinely to diagnose hematoma, to confirm the sampling site, and to establish a new baseline for future mammograms.

Materials And Methods: Stereotaxic core biopsies of 113 mammographically indeterminate or suspicious lesions were performed by use of a dedicated stereotaxic table with digital imaging, a 14-gauge needle, and an automated gun. The indication for biopsy was a mass with or without calcifications in 59 cases (52%) and calcifications without a mass in 54 cases (48%).

Impact of stereotaxic core breast biopsy on cost of diagnosis.

Purpose: To determine the frequency with which stereotaxic core biopsy of the breast obviated diagnostic surgical biopsy and to estimate the savings in cost of diagnosis with this procedure.

Materials And Methods: Stereotaxic core biopsy of 182 nonpalpable, mammographically evident lesions was performed, and data from clinical follow-up were obtained. Savings in cost were assessed by using national Medicare reimbursement data and a relative value system based on national physician reviews (Relative Values for Physicians [RVP]).

Displacement of carcinomatous epithelium in surgical breast specimens following stereotaxic core biopsy.

A variety of needling procedures in the breast may lead to dislodgment and displacement of fragments of breast carcinoma into tissue outside the target lesion of the needling procedure. To assess how frequently displaced fragments of carcinoma are seen in surgical breast specimens following stereotaxic core needle biopsies, slides were reviewed from 43 consecutive cases of breast carcinoma in which surgical excision and/or mastectomy had been performed following an initial diagnostic stereotaxic 14-gauge core biopsy procedure. In 12 of 43 (28%) cases, displaced carcinomatous fragments were identified outside of the main tumor mass.

Atypical ductal hyperplasia diagnosed at stereotaxic core biopsy of breast lesions: an indication for surgical biopsy.

Objective: The purpose of this study was to evaluate the prevalence of carcinoma found at surgical biopsy of lesions identified as atypical ductal hyperplasia by stereotaxic core breast biopsy.

Subjects And Methods: Stereotaxic core biopsies of 264 mammographically evident lesions were done with the patients lying prone on a dedicated stereotaxic table, with an automated gun and a 14-gauge needle. Atypical ductal hyperplasia was identified in 25 (9%) of 264 lesions, including four (3%) of 159 masses and 21 (20%) of 105 lesions evident as calcifications.

Assessment of response to therapy of primary breast cancer by mammography and physical examination.

Background: Accurate assessment of response to treatment is necessary to treat appropriately primary breast cancers that are not surgically removed. This retrospective study was undertaken to compare the effectiveness of physical examination (PE) and mammography to assess response of primary breast cancer to medical therapy in women who were ineligible for initial surgical treatment.

Methods: Thirteen women with 14 breast carcinomas were evaluated for interval changes.

Stereotaxic core biopsy of breast carcinoma: accuracy at predicting invasion.

Purpose: To assess the accuracy with which stereotaxic core biopsy of breast carcinoma predicts the presence of invasion.

Materials And Methods: Stereotaxic core biopsy was performed in 63 breast carcinomas in 59 patients in the prone position. All patients subsequently underwent surgery.

Stereotaxic 14-gauge breast biopsy: how many core biopsy specimens are needed?

Purpose: To determine the optimum number of specimens to obtain at stereotaxic core breast biopsy.

Materials And Methods: Stereotaxic biopsies were performed in 145 mammographically evident lesions by using a dedicated table with patients in the prone position. Samples were obtained with an automated gun and a 14-gauge needle.

Non-Hodgkin lymphoma of the breast: imaging characteristics and correlation with histopathologic findings.

Purpose: To determine the imaging characteristics of non-Hodgkin lymphoma (NHL) of the breast and correlate these findings with histopathologic subtype.

Materials And Methods: The authors retrospectively reviewed records in 32 cases of histologically proved NHL in 29 women. Mammography was performed before biopsy in all cases, and breast sonography was performed before biopsy in eight.

Imaging of pregnancy-associated breast cancer.

Purpose: To assess the use of mammography in diagnosis of pregnancy-associated breast cancer (PABC).

Materials And Methods: A retrospective review of medical records between 1973 and 1993 was performed in 85 women with breast cancer diagnosed during pregnancy or within 1 year after pregnancy. In 21 of these women, mammography was performed before biopsy; the mammographic findings in this study group, which had 23 cases of invasive carcinoma, were reviewed for signs of malignancy.