Leishmania are protozoan parasites that affect humans in various regions, and studying their gene expression can help in understanding their virulence and developing control strategies.
The gene expression in Leishmania primarily involves post-transcriptional regulatory mechanisms, and with the nearing completion of their genome mapping, new research methods are becoming available.
The laboratory has implemented advanced techniques like Drosophila transposon mariner and DNA microarrays to study Leishmania gene regulation, potentially leading to discoveries of genes linked to its virulence.