Achatina fulica haemocyanin-derived peptides as novel antimicrobial agents.

Haemocyanin-derived peptides were previously found in semi-purified fractions of mucus secretion from the snail Achatina fulica, which exhibited an inhibitory effect on Staphylococcus aureus strains. Here, an in silico rational design strategy was employed to generate new antimicrobial peptides (AMPs) from A. fulica haemocyanin-derived peptides (AfH).

Antibacterial, Antibiofilm and Anti-Virulence Activity of Biactive Fractions from Mucus Secretion of Giant African Snail against Strains.

is an important etiological agent that causes skin infections, and has the propensity to form biofilms, leading to significant mortality and morbidity in patients with wounds. Mucus secretion from the Giant African snail is a potential source of biologically active substances that might be an important source for new drugs to treat resistant and biofilm-forming bacteria such as . This study evaluated the effect of semi-purified fractions from the mucus secretion of on the growth, biofilm formation and virulence factors of .