[n]Cycloparaphenylenes as Compatible Fluorophores for Melt Electrowriting.

Fluorescent probes are an indispensable tool in the realm of bioimaging technologies, providing valuable insights into the assessment of biomaterial integrity and structural properties. However, incorporating fluorophores into scaffolds made from melt electrowriting (MEW) poses a challenge due to the sustained, elevated temperatures that this processing technique requires. In this context, [n]cycloparaphenylenes ([n]CPPs) serve as excellent fluorophores for MEW processing with the additional benefit of customizable emissions profiles with the same excitation wavelength.

On the Stability of Electrohydrodynamic Jet Printing Using Poly(ethylene oxide) Solvent-Based Inks.

Electrohydrodynamic (EHD) jet printing of solvent-based inks or melts allows for the producing of polymeric fiber-based two- and three-dimensional structures with sub-micrometer features, with or without conductive nanoparticles or functional materials. While solvent-based inks possess great material versatility, the stability of the EHD jetting process using such inks remains a major challenge that must be overcome before this technology can be deployed beyond research laboratories. Herein, we study the parameters that affect the stability of the EHD jet printing of polyethylene oxide (PEO) patterns using solvent-based inks.

Cryo-Electrohydrodynamic Jetting of Aqueous Silk Fibroin Solutions.

The incorporation of 3D-printing principles with electrohydrodynamic (EHD) jetting provides a harmonious balance between resolution and processing speed, allowing for the creation of high-resolution centimeter-scale constructs. Typically, EHD jetting of polymer melts offers the advantage of rapid solidification, while processing polymer solutions requires solvent evaporation to transition into solid fibers, creating challenges for reliable printing. This study navigates a hybrid approach aimed at minimizing printing instabilities by combining viscous solutions and achieving rapid solidification through freezing.

Melt Electrowriting of Nylon-12 Microfibers with an Open-Source 3D Printer.

This study demonstrates how either a heated flat or cylindrical collector enables defect-free melt electrowriting (MEW) of complex geometries from high melting temperature polymers. The open-source "MEWron" printer uses nylon-12 filament and combined with a heated flat or cylindrical collector, produces well-defined fibers with diameters ranging from 33 ± 4 to 95 ± 3 µm. Processing parameters for stable jet formation and minimal defects based on COMSOL thermal modeling for hardware design are optimized.

Ultrafast 3D printing with submicrometer features using electrostatic jet deflection.

Additive manufacturing technologies based on layer-by-layer deposition of material ejected from a nozzle provide unmatched versatility but are limited in terms of printing speed and resolution. Electrohydrodynamic jetting uniquely allows generating submicrometer jets that can reach speeds above 1 m s, but such jets cannot be precisely collected by too slow mechanical stages. Here, we demonstrate that controlling the voltage applied to electrodes located around the jet, its trajectory can be continuously adjusted with lateral accelerations up to 10 m s.

[Immunological disturbances in psoriatic patients exposed to radionuclides and corrective complex therapy with dibazol and hepatoradioprotective diet].

In an inpatient setting, 67 and 70 patients with psoriasis living in contaminated and uncontaminated with radionuclides territories respectively were studied in the time-related course of some qualitative indices of immunity. Significant deviations from the norm were recordable, especially in those patients residing in the contaminated with radionuclides tcrritiry. Combined treatment involving the use of dibazol and hepatoradioprotective diet in the experiment group of psoriatic patients proved to be significantly more effective than in patients of the control group who were treated by the generally accepted method.

[Ecovariant differences of Escherichia coli strains with respect to colicinogenicity and colicin resistance].

The analysis of 173 Escherichia coli strains, isolated from different sources, for colicinogenicity and colicin resistance revealed that frequency of these signs increased in the following order: water in open reservoirs, intestine, extraintestinal localizations. In most cases resistance to 5 or more bacterial colicins was due to the absence of the corresponding receptors to colicins. Colicin resistance and colicinogenicity render E.

[A nutrient medium for the isolation of escherichiae with persistence properties].

The possibility of establishing the etiological and epidemiological importance of Escherichia on the basis of the determination of their persistence factors made it necessary to develop simple and, at the same time, informative methods for their indication. For this purpose a new selective medium for the isolation of Escherichia with persistence properties was developed and approved. The use of this medium permits the early detection of persistent strains in the process of their isolation from a human body and environmental objects.

[Viral hepatitis A and B in wounded patients].

Virus hepatitis A and B have certain characteristics traits in personnel with gunshot wounds, especially when the wounds are of medium and high degrees of severity. Virus hepatitis A in the injured men is distinguished by shortened initial period, predominantly of dyspeptic or mixed type, as well as by grave and complicated course sometimes ending with lethal outcome. Virus hepatitis B in the injured men is characterized by the absence of pre-icteric period or weakness of its manifestations in many cases, by the prevalence of mild forms of the disease, as well as by increased tendency to development of chronic forms.

[The use of a bioprofile of Escherichia for its epidemiological marking].

The analysis of the penetrating and expressing capacity of the markers of bacterial persistence, adhesive capacity, antibiotic resistance and colicinogenicity in 254 E.coli strains of 7 groups, isolated from different ecotopes, including different environmental objects and bodies of healthy and sick children, revealed the specific character of their population bioprofiles, i.e.

[The information value of Escherichia coli persistence markers in the bacteriological diagnosis of chronic pyelonephritis in children].

In 181 E. coli strains isolated from sick children having chronic pyelonephritis and risk factors of its development, as well as from healthy children, the complex of phenotypic signs, and among them bacterial persistence markers (antilysozyme, anticomplementary and "anti-interferon" activity), adhesive capacity, antibiotic resistance and colicinogenicity, were analyzed. The specific bioprofiles of E.

[The functional status of the body and work capacity of convalescent patients after typhoid fever].

Convalescents (168 patients) who went through typhoid and 48 sound men (control group) were examined in order to study their clinical and physiological indices, mental and performance capabilities. At the end of inpatient treatment the complete normalization of functional state was marked only in group 1 (convalescents after abortive typhoid). In 96% of patients who went through slight form of disease (group 2) and middle-severe form (group 3) different disorders of functional state of organism were marked.

[A comparative evaluation of the persistence characteristics of Escherichia isolated from different econiches].

The multiple evaluation of the persistence characteristics, including antilysozyme, anti-interferon and anticomplement activity, as well as other biological properties, such as adhesiveness, colicinogenicity and resistance to antibiotics, was carried out in 173 E. coli strains isolated from water, healthy and sick children. This evaluation revealed that each group of E.

[The diagnostic and treatment characteristics of diphtheria in troop units and military medical institutions].

Medical records of 876 servicemen of a young age who have suffered various forms of clinical diphtheria were analysed. (Lethal cases were marked in 52 cases--5.9%).

[The clinico-epidemiological characteristics of brucellosis in young people].

The article describes an outbreak of brucellosis among the servicemen (age 19-32) which was caused by Br. melitensis. 13% of servicemen in the military unit went through this disease.

[New elements in organizing medical care for infectious patients in a mountainous desert locale with a hot climate].

In 1983-1985 the author of this article occupied the post of main infectionist of the 40th Army. During this period a number of new elements were elaborated by him to meet the requirements of medical care to infectious patients. At prehospital phase the nonorganic garrison isolators were deployed with 60-100 patient capacity on the basis of medical companies and separate medical battalions taking into account considerable delays in evacuation of patients.

[Characteristics of chemotherapy of infectious diseases associated with gunshot wounds and trauma].

The experience in treating infectious diseases in wounded and traumatized persons from the contingent of the Soviet Troops in ++Afghanistan is described. The syndrome of the joint effect of the injury and infection is characterized. Features of the chemotherapy of the injured patients with viral hepatitis, malaria, typhoid fever and enteric and ++extra-enteric amebiasis under the ecological and professional stress and with an account of the etiology of the wound infection are presented.