[Intranasal vaccination with live measles vaccines within the framework of measles eradication strategy].

The authors discuss the possibility of intranasal revaccination with live measles vaccine. Intranasal vaccination is no less effective than subcutaneous. It induces generalized immune response and formation of anti-measles IgA in the nasopharyngeal mucosa.

[Efficiency of revaccination against epidemic parotitis and immunological safety].

Seventy-eight children aged 6-7 years were subcutaneously revaccinated with L-3 live mumps vaccine. The vaccine is slightly reactogenic and completely safe. The level of antibodies increased on day 10 postvaccination in 80% of children with initially low antibody titers.

[Possibilities of measles vaccination in children with counterindications and duration of preservation of postvaccinal immunity].

A study was made of the clinicoimmunological reactions in 2056 children with different somatic diseases, in children frequently falling ill and in those with tuberculous infection vaccinated against measles. Of these, 912 children were vaccinated after carrying out the treatment and health measures and 1144 children remained without those measures; 192 practically healthy children were vaccinated with the same series of vaccines. The treatment and health measures carried out before vaccination decrease the rate and intensity of the clinical manifestations of the measles vaccinal process and enhance antibody formation.

[Septic metastatic staphylococcal destruction of the lungs in adults].

The author analyzes results of diagnostics and treatment of 152 patients with septic metastatic staphylococcal destruction of the lungs. Specific features of the clinical course of the disease are described. Under consideration are questions of the complex pathogenetic treatment of this group of patients by means of using antibiotic and immune therapy, fat emulsions (lipofundin), exchange plasmapheresis, ultraviolet irradiation of blood etc.

[Study of the biological activity of spleen extracts containing inhibitor of DNA-ase I].

Fractions of calf spleen extracts possessing the increased potency to inhibit the activity of DNase 1 were obtained by chromatography on columns with Sephadex G-200 and CM-cellulose. The fractions containing the most powerful inhibitor of DNase 1 increased the survival rate of sublethally irradiated mice and hamsters. A possible role of the DNase 1 inhibitor in cure effects is discussed.

[Results of the surgical treatment of lung cancer].

Clinical observations and autopsy findings indicate that radical surgery for lung cancer is followed in most cases by tumor progression. The first signs of the progression would more frequently develop during two years postoperatively, and these were due to metastases in distal organs (49.6%) and lymph nodes (35.

[Age aspects of remote outcome of acute lung suppuration].

Among 375 patients (adults and children) having acute suppurative processes in the lung, treated conservatively, 165 were examined in later terms up to 15 years, using modern bronchological methods, considerable changes being revealed in 66.2%: residual cavities, chronic abscesses, bronchitis deformans and bronchiectases. In children suppuration in the lung showed a more grave course, but reparative processes were much better pronounced.

[The relationship between the doubling time of human lung tumor volume and the labelling index].

The value of the labelling index (incubation with H3-thymidine) was compared with the doubling time of tumour volume (by repeated roentgenograms) for 3 tumours of human lungs: two squamous cell carcinomas taken at various differentiation levels and a hamartoma. The minimum doubling time (178 days) was shown for the squamous cell carcinoma with a lower differentiation level and the greatest labelling index value (19.0%).