[Dynamics of a CD3-lymphocytes contents during intraabdominal sorption-transmembranous dialysis in patients with extended peritonitis].

The analysis of clinical and laboratory material in patients, suffering extended peritonitis,was conducted. There was established, that application of the sorption-transmembranous dialysis and abdominal cavity sanation guarantees the CD3 lymphocytes protection and the endotoxicosis severity reduction.

[The sorption therapy in complex treatment of abdominal sepsis].

The results of diagnosis and treatment of 31 patients, suffering abdominal sepsis of various origin, are analyzed. There was elaborated algorithm of postoperative treatment ot the patients. Depending on peculiarities of postoperative tactic of treatment, all the patients were divided into two groups.

[Bile secretion in the liver caused by verapamil].

Verapamil was studied for its effects on secretory function of liver in rats. In the animals with low initial level of bile secretion, infusion of verapamil resulted in increase of the bile flow conjugated with taurine bile salts and ester of cholesterol, and in reduction of the non-conjugated bile salts secretion, as well as bile salts conjugated with glycine. In the animals with high initial level of the liver secretory function, verapamil decreased the bile flow, the secretion of unconjugated bile salts, and bile salts conjugated with taurine and glycine, phospholipids, cholesterol and its ester.

[The action of calcium regulating agents on the biliary secretion of adenyl nucleotides].

Many types of cells release ATP under the action of specific physiological signals. It is known that the ATP and other adenyl nucleotides is involved in the regulation of bile secretion too. The aim of our experiments was to determinate the influence of noradrenaline, fMLP and verapamile on the biliary secretion of adenyl nucleotides in bile-fistula rats.

[Effect of dalargin on the bile acid spectrum in human bile].

Effects were studied of dalargin on the bile acids spectrum in the bile of patients with duodenal ulcer. Dalargin has been shown to increase the bile concentration of tauro- and glycochilates, with the concentration of free bile acids remaining unchanged or being on the decrease.

[The effect of lactin on histamine-stimulated gastric secretion and choleresis].

Lactine was found to depress the level of the histamine secretion of the gastric juice and to reduce the debit of hydrochloric acid in dogs. This peptide suppressed mainly the spontaneous choleresis and alters the compound composition of the bile. Large doses of the hormone obviously suppress the transport of bilirubin into the secret.

[The effect of substance P on histamine-stimulated gastric juice release and bile formation].

The substance P was shown to be able to increase the level of histamine-induced stomach secretion and the debit of free hydrochloric acid in dogs. This peptide increases the volume velocity of the choleresis and the content of bile acids and protein in the bile. The substance P alters the range of the bile acids as well.