The effect of ethanol vapour exposure on atrial and ventricular walls of chick embryos.

Objective: To study the effects of ethanol vapour exposure on atrial and ventricular walls of heart in chick embryo.

Methods: The study design was experimental, conducted at Islamabad Centre of College of Physicians and Surgeons, Pakistan. One hundred and eighty chicken eggs were divided into two groups, experimental and control, of 90 eggs each.

Role of oxidative injury in affecting the foetal & placental weights on exposure to tobacco smoke.

Objective: To investigate the role of oxidative injury in affecting foetal and placental weights in mice by exposing them to tobacco smoke with or without supplementation with antioxidants.

Methods: The randomized control trial of pregnant mice at day one of gestation was conducted at Anatomy Department CPSP Regional Center Islamabad, from March 2005 to October 2005. The mice were divided into three groups: Group C had controls, while the two other groups, groups S and SV were exposed to secondary tobacco smoke in a whole body exposure chamber with and without supplementation with vitamins respectively.

Atrial and ventricular septal changes in ethanol vapour exposed chick embryos.

Objective: To study the effects of ethanol vapour exposure on development of atrial and ventricular septa of chick embryo.

Methods: The experimental study was conducted at the College of Physicians and Surgeons, Islamabad, from 2006 to 2007. The experimental and control groups were further divided into three subgroups based on the day of sacrifice.

The effect of prenatal administration of valproic acid on the survivability and day of hatching of chick embryo.

Objective: To assess the effects of prenatal administration of valproic acid on the survivability and day of hatching of chick embryo in comparison with age-matched controls.

Methods: The experimental study was conducted at the Department of Anatomy, Regional Centre of College of Physicians and Surgeons Pakistan, Islamabad, from February 2010 to February 2011. Fertilised chicken eggs were divided into two groups, labelled as experimental group-A and control group-B.

Wound healing in rat skin subjected to loud noise stress; a light microscopic study.

Objective: To determine the effect of loud noise stress on wound healing in a skin tissue.

Methods: The randomised control trial was conducted at the Department of Anatomy, College of Physicians and Surgeons Pakistan Regional Centre, Islamabad, from September 2007 to September 2008. The study comprised 240 male Sprague Dawley rats who were randomised into control group A and experimental group B.

The developmental gross morphology of pancreas in chick embryo after prenatal administration of valproic acid.

Objective: To determine the effects of prenatal administration of valproic acid on the developmental gross morphology of pancreas in chick embryo.

Study Design: Experimental study.

Place And Duration Of Study: Anatomy Department, Regional Centre, College of Physicians and Surgeons, Islamabad, from February 2010 to February 2011.

Quantitative analysis of macrophages in wound healing of rat skin subjected to loud noise stress.

Background: Factors affecting skin wound healing have always been a central consideration in medical practice. Loud noise is biological stressor affecting the body systems at various levels. The present study was taken to study the effect of loud noise stress on the macrophages during wound healing process in male rat skin.

Ethanol vapour induced dilated cardiomyopathy in chick embryos.

Objective: To study the effects of ethanol vapour inhalation on the heart chambers of chick embryo.

Methods: The case-control study was conducted at the College of Physicians and Surgeons Pakistan regional centre in Islamabad from January to October 2007. Both experimental and control groups were divided into three subgroups each, based on the day of the sacrifice.

Effects of immobilisation and re-mobilisation on superficial zone of articular cartilage of patella in rats.

Objective: To determine the staining grades and morphological changes in the cells of articular cartilage of patella on immobilisation and re-mobilisation in rats.

Methods: A total of 120 Sprague Dawley rats were divided into four groups of 30 animals. The study was done between July and December 2009.

Effect of passive cigarette smoke on mouse placenta and the role of antioxidants.

Objective: To study the effects of passive cigarette smoke on the architecture of mouse placenta and to observe the preventive role of antioxidants if any.

Methods: It was a randomized control trial. Female mice of Balb C strain (51) were mated and grouped as follows: Groups, C: control, S: exposed to smoke and SV: exposed to smoke and given antioxidants (vitamin C, E) and sacrificed at 19 dpc (days post coitus).

A comparative histological study of the surface epithelium and high endothelial venules in the subepithelial compartments of human nasopharyngeal and palatine tonsils.

Objective: To compare the thickness and organization of surface epithelium, and high endothelial venules in subepithelial compartments of human nasopharyngeal and palatine tonsils, with reference to functional differences.

Study Design: Comparative cross-sectional.

Place And Duration Of Study: The Anatomy Department of CPSP Regional Centre, Islamabad, from January to December 2005.

Effect of ethanol vapour exposure on survival of chick embryos.

Objective: To determine the survival of chick embryos after ethanol vapour exposure by noting the number of dead and alive embryos and comparing with age-matched controls.

Study Design: Experimental study.

Place And Duration Of Study: Department of Anatomy at the regional centre of College of Physicians and Surgeons, Islamabad, from February 2006 to February 2007.

Derangement of chick embryo retinal differentiation caused by radiofrequency electromagnetic fields.

The possible adverse effects of radiofrequency electromagnetic fields (EMF) emitted from mobile phones present a major public concern. Biological electrical activities of the human body are vulnerable to interference from oscillatory aspects of EMF, which affect fundamental cellular activities, in particular, the highly active development process of embryos. Some studies highlight the possible health hazards of EMF, while others contest the hypothesis of biological impact of EMF.

Influence of cimetidine and bromocriptine on prolactin levels in rat fertility.

The present study was designed to see the effects of parenterally administered drugs cimetidine and bromocriptine affecting serum prolactin upon the fertility of adult male albino rats. Ninety adult young male albino rats between the ages of 60 to 120 days were selected. The animals were divided into three groups.

Dose related shifts in the developmental progress of chick embryos exposed to mobile phone induced electromagnetic fields.

Background: The possible adverse effects of Electromagnetic Fields (EMFs) emitted from mobile phones present a major public concern today. Some studies indicate EMFs effects on genes, free radical production, immunological and carcinogenic effects. On the other hand there are studies which do not support the hypothesis of any biological impacts of EMFs.

Effect of passive tobacco smoking on fertility of female mice.

Objective: To determine the adverse effects of passive tobacco smoking on fertility of female mice and the preventive role of antioxidants, if any.

Study Design: Randomized controlled trial.

Place And Duration Of Study: Anatomy Department, CPSP Regional Centre, Islamabad, from February to July 2005.