Publications by authors named "Liansheng Ruan"
Objectives: Homocysteine is a modifiable, independent risk factor for cardiovascular disease. The association between hyperhomocysteinemia and metabolic syndrome with the presence of early carotid artery atherosclerosis remains unknown in middle-aged Chinese adults.
Methods: Chinese adults (n = 1607) of Han ethnicity, age 35 to 65 y, and living in their communities >2 y were surveyed.
Article Synopsis
- Metabolic syndrome (MetS) is linked to genetic factors and environmental influences, increasing the risk for heart disease and diabetes.
- Researchers conducted a genome-wide association study with over 12,720 participants in China, identifying new genetic signals related to triglyceride levels, particularly highlighting the role of the BUD13 gene alongside the established APOA5 signal.
- The study also found that the ALDH2 gene variant (rs671), common in East Asians, is associated with MetS, with stronger effects observed in individuals who consume alcohol.
Magnesium (Mg) and calcium (Ca) are essential for numerous kinds of metabolisms in human body. To investigate the associations between Mg and Ca and the ratio of Ca to Mg (Ca/Mg) in whole blood with metabolic syndrome (MetS) in a Chinese population, a matched case-control study including 204 MetS patients and 204 healthy controls (aged 48-89) was carried out in 2011. MetS were diagnosed according to the criteria of Chinese Diabetes Society.
View Article and Find Full Text PDF[Incidence of obesity and its modifiable risk factors in Chinese adults aged 35-74 years: a prospective cohort study].
Zhonghua Liu Xing Bing Xue Za Zhi
April 2014
Objective: To examine the incidence of obesity and its modifiable risk factors in Chinese adults aged 35-74 years.
Methods: A total of 27 020 participants aged 35 to 74 years from two prospective cohort studies in China were followed up in the years of 2007 and 2008. Obesity and overweight were defined as body mass index ≥ 28.
Objective: To investigate the association between physical activity (PA) and the incidence of metabolic syndrome (MS) in Chinese adults.
Methods: Data on PA and other variables were obtained at the baseline examination of China Multi-center study of Cardiovascular Epidemiology in 1998 and of International Collaborative study of Cardiovascular Disease in Asia(InterASIA) during 2000 - 2001. Follow-up study was conducted in 2007 - 2008.