Isolation of Helicobacter pylori from the intestinal mucosa of patients with Crohn's disease.

Background: Helicobacter species are associated with inflammatory bowel disease in rodents and in nonhuman primates. Therefore, we prospectively investigated the presence of Helicobacter species in the intestinal mucosa of patients with and without Crohn's disease by culture and polymerase chain reaction (PCR) assays.

Materials And Methods: Mucosal fragments were obtained from the ileum, different colon regions, and rectum of 43 patients with Crohn's disease and of 74 patients without inflammatory bowel disease.

Helicobacter species in the intestinal mucosa of patients with ulcerative colitis.

In a search for Helicobacter species in the intestinal mucosae of 42 patients with ulcerative colitis (UC) and 74 without UC, only H. pylori was found. Although the bacterium was detected in UC patients by culture (7.

Factors associated with treatment failure of Helicobacter pylori infection in a developing country.

Background: Although no regimen can eradicate in 100% of patients, factors that may affect the eradication rates have been poorly studied.

Goal: To evaluate factors associated with treatment failure.

Study: One hundred patients were treated with pantoprazole plus clarithromycin and furazolidone for eradication.