Predicting Preoperative Pathologic Grades of Bladder Cancer Using Intravoxel Incoherent Motion and Amide Proton Transfer-Weighted Imaging.

Rationale And Objectives: To investigate the predictive value of intravoxel incoherent motion (IVIM) combined with amide proton transfer-weighted (APTw) imaging for the preoperative grading of bladder cancer (BC).

Materials And Methods: A total of 69 patients with histopathologically confirmed BC underwent diffusion-weighted imaging (DWI), IVIM, and APTw imaging at 3.0 T MRI.

Research on the Causes of Gas Explosion Accidents Based on Safety Information Transmission.

To better explain the cause of gas explosion accidents, based on the existing accident-causation theory, this paper proposes an accident-causation model of gas explosion accidents based on safety information transmission. Based on this, a new method for the prevention of gas explosion accidents can be developed. By analysing the connection between safety information transmission and the causal factors of gas explosion accidents, it is inferred that the loss of safety information transmission is the key factor leading to accidents.

Demethylzeylasteral exhibits strong inhibition towards UDP-glucuronosyltransferase (UGT) 1A6 and 2B7.

Inhibition of UDP-glucuronosyltransferase (UGT) isoforms can result in severe clinical results, including clinical drug-drug interactions (DDI) and metabolic disorders of endogenous substances. The present study aims to investigate the inhibition of demethylzeylasteral (an important active component isolated from Tripterygium wilfordii Hook F.) towards three important UGT isoforms UGT1A6, UGT1A9 and UGT2B7.