Novel miRNA markers and their mechanism of esophageal squamous cell carcinoma (ESCC) based on TCGA.

MicroRNAs(miRNAs) are promising biomarkers for early esophageal squamous cell carcinoma (ESCC) detection and prognostic prediction. This study aimed to explore the potential biomarkers and molecular pathogenesis in the early diagnosis of ESCC. Firstly, 48 differentially expressed miRNAs (DEMs) and 1319 differentially expressed genes (DEGs) were identified between 94 ESCC tissues and 13 normal esophageal tissues in TCGA.

Interplay of Trapped Species and Absence of Electron Capture in Moiré Heterobilayers.

Moiré heterobilayers host interlayer excitons in a natural, periodic array of trapping potentials. Recent work has elucidated the structure of the trapped interlayer excitons and the nature of photoluminescence (PL) from trapped and itinerant charged complexes such as interlayer trions in these structures. In this paper, our results serve to add to the understanding of the nature of PL emission and explain its characteristic blueshift with increasing carrier density, along with demonstrating a significant difference between the interlayer exciton-trion conversion efficiency as compared to both localized and itinerant intralayer species in conventional monolayers.

Co-designed metaoptoelectronic deep learning.

A metaoptical system is co-designed with electronic hardware to implement deep learning image recognition. The optical convolution block includes a reflective metasurface to perform one layer of a deep neural network. The optical and digital components are jointly optimized to perform an image classification task attaining 65% accuracy, which is close to the 66% accuracy of a fully-digital network where the optical block is replaced by a digital convolution layer.

Molecular Polaritons Generated from Strong Coupling between CdSe Nanoplatelets and a Dielectric Optical Cavity.

We demonstrate the formation of CdSe nanoplatelet (NPL) exciton-polaritons in a distributed Bragg reflector (DBR) cavity. The molecule-cavity hybrid system is in the strong coupling regime with an 83 meV Rabi splitting, characterized from angle-resolved reflectance and photoluminescence measurements. Mixed quantum-classical dynamics simulations are used to investigate the polariton photophysics of the hybrid system by treating the electronic and photonic degrees of freedom (DOF) quantum mechanically and the nuclear phononic DOF classically.

Mechanically tunable focusing metamirror in the visible.

A compact, flat lens with dynamically tunable focal length will be an essential component in advanced reconfigurable optical systems. One approach to realize a flat tunable lens is by utilizing metasurfaces, which are two-dimensional nanostructures capable of tailoring the wavefront of incident light. When a metasurface with a hyperboloidal phase profile, i.

Polarization-switchable holograms based on efficient, broadband multifunctional metasurfaces in the visible regime.

Gradient metasurfaces provide a novel approach to the phase manipulation of incident electromagnetic waves. Thus, they have the potential to create compact, light-weight optical solutions. An attractive feature of metasurfaces is the ability to integrate multiple optical functionalities into a single surface design.

3D Localized Trions in Monolayer WSe in a Charge Tunable van der Waals Heterostructure.

Monolayer transition metal dichalcogenides (TMDCs) have recently emerged as a host material for localized optically active quantum emitters that generate single photons. (1-5) Here, we investigate fully localized excitons and trions from such TMDC quantum emitters embedded in a van der Waals heterostructure. We use direct electrostatic doping through the vertical heterostructure device assembly to generate quantum confined trions.