Publications by authors named "Liangxue Zhu"
Article Synopsis
- KDM1A is overexpressed in epithelial ovarian cancer (EOC) and plays a significant role in promoting malignant behaviors of EOC cells.
- The study utilized various assays and mouse models to investigate the effects of KDM1A, ZFP64, and CENPL on EOC cell functions and found that knocking down these proteins inhibited EOC cell behavior.
- The research concluded that KDM1A enhances EOC progression through the activation of the ZFP64/CENPL pathway, promoting cell proliferation, migration, and invasion while reducing apoptosis.
The aim of this study is to investigate the role of CDGSH iron-sulfur domain 2 (CISD2) in colorectal cancer (CRC). The purpose of this study was to investigate the role of CDGSH iron-sulfur domain 2 (CISD2) in colorectal cancer (CRC) progression. The expression of CISD2 in CRC cell lines was measured by western blotting.
View Article and Find Full Text PDFPurpose: Colon cancer is a common malignant tumor of the digestive system. This project verified the negative role of protein tyrosine phosphatase (SHP-2) in the regulation of colon cancer and further clarified the key targets and molecular mechanisms in the regulation process.
Patients And Methods: The expression levels of SHP-2 in colon cancer tissues, adjacent tissues, normal colon cell lines, and cancer cell lines were detected via Quantitative Real-time PCR (qRT-PCR).