Sepsis is defined as a life-threatening organ dysfunction syndrome caused by dysregulated host response to infection, characterized by a systemic inflammatory response to infection. The use of antibiotics, fluid resuscitation, and organ support therapy has limited prognostic benefit in patients with sepsis, and its incidence is not diminishing, which is attracting increased attention in medicine. Sepsis remains one of the most debilitating and expensive illnesses.
View Article and Find Full Text PDFObjective: To investigate the impact of different treatment methods on cerebrospinal fluid (CSF) cytokine detection.
Methods: CSF samples were collected from 25 patients. The levels of IL-6, IL-10, IFN-γ, and IL-2 were measured after CSF was stored at room temperature (25°C) or 4°C for 6, 12, and 24 hrs.
Objective: The purpose of this study was to investigate whether local application of methyl nicotinate solution can change the content and proportion of blood cells in peripheral blood samples and to determine whether this treatment is a safe and reliable method for improving peripheral blood collection.
Methods: Routine blood analysis and flow cytometry were used to analyze the contents and proportions of blood cells and T lymphocyte subsets in peripheral blood samples. Experimental blood specimens were collected from earlobes treated with different concentrations of methyl nicotinate solution, and the control group consisted of blood specimens collected from untreated earlobes.
Objective: To investigate the plasma fibrinogen gamma-chain concentration in preeclampsia patients and explore its value in preeclampsia prediction and auxiliary diagnosis.
Methods: Follow-up of pregnant women who regularly attended perinatal care at two hospitals in China was performed, and clinical data and plasma samples were collected at each examination until delivery. The gamma-chain concentration was detected by Western blotting, and Quantity One Software was used for gamma-chain grayscale value measurements.
Objective: To investigate the values of CD64 and CD11b indices of peripheral white blood cells in the early diagnosis of acute exacerbation of chronic obstructive pulmonary disease (AE-COPD) in older adults.
Methods: The study enrolled 86 aged AE-COPD patients, 82 stable-COPD patients admitted in the affiliated hospital of Jiujiang University from March 2011 to December 2013, and simultaneously 84 healthy aged volunteers as a control group. All the subjects were examined in white blood cells, hypersensitive C-reactive protein (hs-CRP), mean fluorescence intensity (MFI) of CD64 and CD11b from peripheral white blood cells within 24 hours after admission.