Synopsis of recent research by authors named "Liangkun Weng"
- Liangkun Weng's research primarily investigates the molecular mechanisms underlying inflammatory diseases and metabolic disorders, focusing on the role of NLRP3 inflammasome and E3 ubiquitin ligases.
- One significant study shows that N-butanol extract from Broussonetia papyrifera root bark alleviates atopic dermatitis by promoting NLRP3 degradation through targeting E3 ubiquitin ligase WWP1.
- Another key finding indicates that hyperhomocysteinemia activates the NLRP3 inflammasome, contributing to hepatic steatosis and insulin resistance via MDM2-mediated ubiquitination of heat shock factor 1.
