Joint Segmentation of Multi-Class Hyper-Reflective Foci in Retinal Optical Coherence Tomography Images.

Hyper-reflective foci (HRF) refers to the spot-shaped, block-shaped areas with characteristics of high local contrast and high reflectivity, which is mostly observed in retinal optical coherence tomography (OCT) images of patients with fundus diseases. HRF mainly appears hard exudates (HE) and microglia (MG) clinically. Accurate segmentation of HE and MG is essential to alleviate the harm in retinal diseases.

Algorithm for Detection and Quantification of Hyperreflective Dots on Optical Coherence Tomography in Diabetic Macular Edema.

To develop an algorithm to detect and quantify hyperreflective dots (HRDs) on optical coherence tomography (OCT) in patients with diabetic macular edema (DME). Twenty OCTs (each OCT contains 128 b scans) from 20 patients diagnosed with DME were included in this study. Two types of HRDs, hard exudates and small HRDs (hypothesized to be activated microglia), were identified and labeled independently by two raters.