The dysregulation of protein-coding genes involved in various biological functions is closely associated with the progression of thyroid cancer. This study aimed to investigate the effects of dysregulated gene expressions on the prognosis of classical papillary thyroid carcinoma (cPTC). Using expression profiling datasets from the Cancer Genome Atlas (TCGA) database, we performed differential expression analysis to identify differentially expressed genes (DEGs).
View Article and Find Full Text PDFThe use of antagonistic microorganisms and their volatile organic compounds (VOCs) to control plant fungal pathogens is an eco-friendly and promising substitute for chemical fungicides. In this work, endophytic bacterium ETR-B22, isolated from the root of Gagnep., was found to exhibit strong antagonistic activity against 12 fungal pathogens found in agriculture.
View Article and Find Full Text PDFThree new substituted bithiophenes (⁻), and one new sulf-polyacetylene ester, ritroyne A () were isolated from the whole plant of together with twelve known substituted thiophenes. The structures were elucidated on the basis of extensive spectroscopic analysis including 1D and 2D NMR as well as MS. Furthermore, the absolute configuration of ritroyne A () was established by computational methods.
View Article and Find Full Text PDFThis work, for the first time, investigated the diversity of endophytic fungi harbored in the xylem and phloem of the root of Sophora tonkinensis Gapnep from three geographic localities with emphasis on the influence of the tissue type and geographic locality on endophytic fungal communities and their potential as biocontrol agents against phytopathogens of Panax notoginseng. A total of 655 fungal strains representing 47 taxa were isolated. Forty-two taxa (89.
View Article and Find Full Text PDFGuang Pu Xue Yu Guang Pu Fen Xi
December 2008
Quaternized polyvinyl alcohol (QAPVA) and phosphate monoester polyvinyl alcohol (PMPVA) were self-assembled into polyion complex (PIC) membrane. The infrared spectra (IR) of PIC membrane dipped in 95% ethanol for 48 h were studied in the temperature range of 20-120 degrees C with an interval of 20 degrees C by analyzing the temperature dependent variations of OH stretch vibration base bands (upsilonOH) at >3000 cm(-1). Hydrogen-bond of water in 95% ethanol with PIC was studied.
View Article and Find Full Text PDFFour new triterpenoids, kadlongilactones C-F (2-5), containing a consecutive hexacyclic [7,7,5,6,6,6] ring system, were isolated from the leaves and stems of Kadsura longipedunculata. In comparison with the NMR data of kadlongilactones A (1) and D (3), a significant phenomena was discovered that ring D of 3 inverted from a half-chair in 1 to a half-boat conformation when the HO-16 group changed from alpha- to beta-orientation. The structures of 2-5 were established on the basis of detailed spectroscopic analysis, and DFT computational methods were applied in the structural validation of compounds 3 and 5.
View Article and Find Full Text PDF[structure: see text]. A new hexacyclic alkaloid, calydaphninone (1), containing a 4-azatricyclo[5.2.
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