Synopsis of recent research by authors named "Liang Yuh Chew"
- Liang Yuh Chew's recent research focuses on the molecular mechanisms governing neural stem cell (NSC) dynamics, highlighting processes such as SUMOylation, autophagy, and specific signaling pathways that affect NSC reactivation and regeneration in Drosophila, essential for tissue homeostasis.
- The studies collectively reveal the intricate interplay of cellular pathways, including the Nrf2-Keap1 signaling in relation to ecdysone and their roles in processes like dendrite pruning, a critical aspect of neural network development and remodeling.
- Chew's findings emphasize the significance of microtubule dynamics and specific proteins, such as Patronin and Msps, in NSC functionality and dendrite morphology, providing insights relevant to understanding neurodevelopmental and neurodegenerative conditions in a broader context.