Readmission of patients with hypertriglyceridemia-induced acute pancreatitis: a prospective cohort study.

Background: Acute pancreatitis (AP) is a common cause of acute hospital admissions in digestive system diseases. In East Asia, hypertriglyceridemia is gradually emerged as the second most common cause of pancreatitis. Vigilance for recurrence and unplanned readmissions due to other causes is still necessary after discharge.

Mesenchymal stem cells therapy for the treatment of non-union fractures: a systematic review and meta-analysis.

Background: This meta-analysis aimed to pool the existing evidence to determine the clinical efficacy and safety of mesenchymal stem cells (MSC) in patients with non-unions.

Methods: A systematic search in PubMed and Scopus was performed until October 2024 to gather pertinent studies. The inclusion criteria included participants with non-unions, the intervention of MSC administration, a comparator of standard treatment (bone graft), and outcomes focused on healing rate, healing time, or side effects.

MiR-146a Reduces Inflammation in Experimental Pancreatitis via the TRAF6-NF-κB Signaling Pathway in Mice.

Background: The initial inflammatory response plays a pivotal role in the development of acute pancreatitis. MiR-146a is believed to play a key role in negatively regulating inflammation and potentially contributes to anti-inflammatory activity in acute pancreatitis, though its mechanism remains largely unexplored.

Objectives: This study aimed to explore the effects of miR-146a on AP in mice and clarify its regulatory mechanisms in pancreatic inflammation and damage.

Shapley-based saliency maps improve interpretability of vertebral compression fractures classification: multicenter study.

Purpose: Evaluate the classification performance and interpretability of the Vision Transformer (ViT) model on acute and chronic vertebral compression fractures using Shapley significance maps.

Materials And Methods: This retrospective study utilized medical imaging data from December 2018 to December 2023 from three hospitals in China. The study included 942 patients, with imaging data comprising X-rays, CTs, and MRIs.

Simultaneously ammonium and perchlorate remove via the partial nitrification-anammox coupled sulfur autotrophic system.

In this study, partial nitrification-anammox coupled sulfur autotrophic (PNA-SA) system was constructed for removing ammonium and perchlorate from composite wastewater simultaneously. The removal rates of ammonium and perchlorate could reach 94.2% and 93.

Evaluating the effectiveness of ultrasound-assisted wound debridement in managing diabetic foot ulcers: A systematic review and meta-analysis.

Background: Diabetic foot ulcers (DFUs) present a significant clinical challenge due to their high prevalence and profound impact on morbidity. Ultrasound-assisted wound debridement (UAWD) has emerged as a potential therapeutic modality to improve healing outcomes in DFU management.

Aim: To evaluate the efficacy of UAWD in treating DFUs on wound closure rates, treatment duration, and quality of life outcomes.

Differential contributions of microbial necromass to humic acid during composting of organic wastes.

Microbial necromass is a crucial source of stable organic matter in composting, yet its role in the humification process remains poorly understood. This study aims to explore the contribution of microbial necromass carbon (MNC) to humic acid (HA) formation during the composting of sewage sludge (SS), kitchen waste (KW), and pig manure (PM), and to examine the involvement of fungal communities in microbial necromass humification. The results show that fungal necromass carbon (FNC) consistently contributes more to MNC than bacterial necromass carbon (BNC), with FNC accounting for over 60% of MNC across all treatments.

Pattern Separation and Pattern Completion Within the Hippocampal Circuit During Naturalistic Stimuli.

Pattern separation and pattern completion in the hippocampus play a critical role in episodic learning and memory. However, there is limited empirical evidence supporting the role of the hippocampal circuit in these processes during complex continuous experiences. In this study, we analyzed high-resolution fMRI data from the "Forrest Gump" open-access dataset (16 participants) using a sliding-window temporal autocorrelation approach to investigate whether the canonical hippocampal circuit (DG-CA3-CA1-SUB) shows evidence consistent with the occurrence of pattern separation or pattern completion during a naturalistic audio movie task.

Connectome-based biophysical models of pathological protein spreading in neurodegenerative diseases.

Neurodegenerative diseases are a group of disorders characterized by progressive degeneration or death of neurons. The complexity of clinical symptoms and irreversibility of disease progression significantly affects individual lives, leading to premature mortality. The prevalence of neurodegenerative diseases keeps increasing, yet the specific pathogenic mechanisms remain incompletely understood and effective treatment strategies are lacking.

Determinants of conventional and contrast-enhanced ultrasound diagnosis of fat-poor angiomyolipoma <5 cm.

Purpose: This study aims to assess the diagnostic efficacy of conventional ultrasound (CUS) and contrast-enhanced ultrasound (CEUS) in detecting fat-poor angiomyolipomas(AML) with dimensions less than 5 cm. Additionally, the study seeks to identify independent indicators for predicting the presence of fat-poor AML.

Methods: We conducted a retrospective analysis of patients diagnosed with renal AML and renal cell carcinoma, who were admitted and underwent surgery at Fujian Provincial Hospital from January 2013 to October 2023.

The Spatial Distribution of Brain Metastasis Is Determined by the Heterogeneity of the Brain Microenvironment.

It is now understood that brain metastases do not occur randomly but have distinct spatial patterns depending on the origin of the cancer. According to the "seed and soil" hypothesis, the final colonization of metastatic cells is the result of their adaptation to the altered environment. To investigate the most favorable microenvironment for brain metastasis, we analyzed neuroimaging data from 177 patients with breast cancer brain metastasis and 548 patients with lung cancer brain metastasis to create a replicable probabilistic map of metastatic locations.

Picosecond Lifetimes of Hydrogen Bonds in the Halide Perovskite CHNHPbBr.

The structures and properties of organic-inorganic perovskites are influenced by the hydrogen bonding between the organic cations and the inorganic octahedral networks. This study explores the dynamics of hydrogen bonds in CHNHPbBr across a temperature range from 70 to 350 K, using molecular dynamics simulations with machine-learning force fields. The results indicate that the lifetime of hydrogen bonds decreases with increasing temperature from 7.

Prognostic Factors in Postoperative Brain Metastases Derive From Non-small Cell Lung Cancer: A Retrospective Analysis.

Background: Brain metastases are crucial in cancer progression, requiring focused efforts on the screening, early detection, and treatment. However, accurate forecasting the postoperative prognosis of patients with non-small cell lung cancer brain metastasis remains a challenge. This retrospective study aims to discern the factors that influence the prognosis of such patients.

Keystone taxa drive the synchronous production of methane and refractory dissolved organic matter in inland waters.

The production of both methane (CH) and refractory dissolved organic matter (RDOM) depends on microbial consortia in inland waters, and it is unclear yet the link of these two processes and the underlying microbial regulation mechanisms. Therefore, a large-scale survey was conducted in China's inland waters, with the measurement of CH concentrations, DOM chemical composition, microbial community composition, and relative environmental parameters mainly by chromatographic, optical, mass spectrometric, and high-throughput sequencing analyses, to clarify the abovementioned questions. Here, we found a synchronous production of CH and RDOM linked by microbial consortia in inland waters.

Chisco: An EEG-based BCI dataset for decoding of imagined speech.

The rapid advancement of deep learning has enabled Brain-Computer Interfaces (BCIs) technology, particularly neural decoding techniques, to achieve higher accuracy and deeper levels of interpretation. Interest in decoding imagined speech has significantly increased because its concept akin to "mind reading". However, previous studies on decoding neural language have predominantly focused on brain activity patterns during human reading.

A retrospective comparative study of extensive sinus membrane perforations repairing using collagen membranes with pouch and nonpouch techniques.

Objectives: To evaluate the clinical and radiological outcomes of employing collagen membranes with pouch and nonpouch techniques to repair extensive maxillary sinus membrane perforation.

Study Design: Patients who experienced extensive maxillary sinus membrane perforation (>10 mm) during lateral window maxillary sinus floor elevation (LWMSFE) were included and treated with either the pouch or nonpouch techniques.

Results: The number of patients treated with the pouch technique and those treated with the nonpouch technique was 10 each.

The protective effect of specific yolk antibody against nervous necrosis virus infection in Mandarin fish(Siniperca chuatsi).

Nervous necrosis virus (NNV), a member of the Nodavirus genus, is a highly contagious disease that is found all over the world. As of right now, there aren't many reliable commercial vaccines available to combat this infection. In a previous study, we isolated a Mandarin fish (Siniperca chuatsi)-derived NNV strain, tentatively named MFNNV.

Changes of bacterial necromass and their roles in humus conversion during organic wastes composting from different sources.

This study compared the changes of bacterial necromass carbon (BNC) in composting of three distinct organic wastes [sewage sludge (SW), kitchen waste (KW), and pig manure (PM)] and their relationship with bacterial communities and humus formation. Results revealed that BNC content significantly differed across treatments, with KW exhibiting the highest level at 13 mg/g, followed by PM, where BNC changed between 8 % and 444 % of microbial biomass. Humification index and degree of polymerization indicated that PM had higher humification potential.

Ten-year survival outcomes of video-assisted thoracic surgery open major lung resection for stage I-III non-small cell lung cancer: a large cohort study in China.

Background: Despite the widespread adoption of video-assisted thoracoscopic surgery (VATS) for major lung resection, the 10-year long-term survival outcomes of non-small cell lung cancer (NSCLC) treated with VATS compared with open major lung resection is lacking. The purpose of this study was to analyze the short- and long-term outcomes of VATS open major lung resection for NSCLC.

Methods: The perioperative outcomes and long-term survival of p-stage I-III NSCLC patients who underwent major lung resection via VATS open major lung resection in the Western China Lung Cancer Database (WCLCD) between May 2006 and June 2018 were studied using propensity score matching (PSM).

Expression of CREBBP and EP300 Associated With Tumor Volume in Patients With Grade-3 Glioma: A Retrospective Analysis.

Background: Reliable predictive data are crucial for making accurate treatment decisions in glioma patients, but it can be challenging to obtain due to limited information in many cases. Numerous research studies have indicated the involvement of cyclic adenosine monophosphate (cAMP)-response element binding protein (CREBBP) and E1A binding protein p300 (EP300) in tumorigenesis and tumor progression across various types.

Methods: The messenger RNA (mRNA) expression levels of CREBBP and EP300 were retrospectively analyzed in 17 grade-3 glioma patients.

Silencing of TXNIP attenuates oxidative stress injury in HEI-OC1 by inhibiting the activation of NLRP3 and NF-κB.

Sensorineural hearing loss (SNHL) is the most common type of hearing loss worldwide. The primary mechanism is oxidative injury to the cochlea as a result of oxidative stress. Therefore, exploring antioxidant strategies is particularly important in addressing SNHL.