Acid-Induced in Situ Phase Separation and Percolation for Constructing Bi-Continuous Phase Hydrogel Electrodes With Motion-Insensitive Property.

Conducting polymer hydrogels have gained attention in the bioelectronics field due to their unique combination of biocompatibility and customizable mechanical properties. However, achieving both excellent conductivity and mechanical strength in a hydrogel remains a significant challenge, primarily because of the inherent conflict between the hydrophobic nature of conducting polymers and the hydrophilic characteristics of hydrogels. To address this issue, this work proposes a simple one-step acid-induced approach that not only promotes the gelation of hydrophilic polymers but also facilitates the in situ phase separation of hydrophobic conducting polymers under mild conditions.

Synergistic effects of carbon and heat under disturbance of human activities: Evidence from a resource-based city of China.

For resource-based cities, the rapid development of industrialization and urbanization has led to significant carbon emissions (CEs), accelerated the rise of urban land surface temperatures (LSTs) and hindered sustainable urban development. This study constructed a model to measure the carbon-heat relationship to clarify the complex relationship between LSTs and CEs in resource-based cities. The results show that:1) High-temperature areas are primarily concentrated around the urban center and large industrial zones, with average LSTs reaching a peak of 35.

Arsenic exposure at environmentally relevant levels induced metabolic toxicity in development mice: Mechanistic insights from integrated transcriptome and metabolome.

Emerging evidence has linked arsenic exposure and metabolic homeostasis, but the mechanism is incompletely understood, especially at relatively low concentrations. In this study, we used a mouse model to evaluate the health impacts and metabolic toxicity of arsenic exposure in drinking water at environmentally relevant levels (0.25 and 1.

An Hsp70 promoter-based mouse for heat shock-induced gene modulation.

Physical therapy is extensively employed in clinical settings. Nevertheless, the absence of suitable animal models has resulted in an incomplete understanding of the in vivo mechanisms and cellular distribution that respond to physical stimuli. The objective of this research was to create a mouse model capable of indicating the cells affected by physical stimuli.

How to perceive and map the synergy between CO and air pollutants: Observation, measurement, and validation from a case study of China.

Cities occupy a central position in addressing climate change and promoting sustainable regional development. Synergistic control of urban gas emissions at the city level is one of the main issues typically explored. The confounding effect and the interactions between the urban indicators of population and area have been ignored in previous studies.

An Ultra-Low-Power Analog Multiplier-Divider Compatible with Digital Code for RRAM-Based Computing-in-Memory Macros.

This manuscript presents an ultra-low-power analog multiplier-divider compatible with digital code words, which is applicable to the integrated structure of resistive random-access memory (RRAM)-based computing-in-memory (CIM) macros. Current multiplication and division are accomplished by a current-mirror-based structure. Compared with digital dividers to achieve higher precision and operation speed, analog dividers present the advantages of a reduced power consumption and a simple circuit structure in lower precision operations, thus improving the energy efficiency.

Single nanowire-based fluorescence lifetime thermometer for simultaneous measurement of intra- and extra-cellular temperatures.

A silicon nanowire-based fluorescence lifetime thermometer (NWFLT) was fabricated for the simultaneous measurement of intra- and extra-cellular temperatures. Using the NWFLT, an obvious heterogeneity of the temperature was found along the longitude direction of the NWFLT, especially between the inside and outside of the cell.

Tubular Polypyrrole with Chloride Ion Dopants as an Ultrafast Organic Anode for High-Power Lithium-Ion Batteries.

Polypyrrole (PPy), as a representative p-type conductive polymer, attracts wide attention for energy storage materials. However, the sluggish reaction kinetics and low specific capacity of PPy impede its application in high-power lithium-ion batteries (LIBs). Herein, tubular PPy with chloride and methyl orange (MO) anionic dopants is synthesized and investigated as an anode for LIBs.

The spatial configuration of buildings: A vital consideration impossible to ignore in regulating urban land surface temperature? Evidence from 35 Chinese cities.

Land urbanization not only efficiently met the requirements of social development but also brought severe heating effects, especially the changes in Land Surface Temperature (LST). The effects of building density on LST and driving relation of the configuration of buildings remain poorly understood over large areas. Using Landsat 8 satellite imagery acquired from the summer of 2019, this study quantified the heating effects (k) of building density on LST across 35 cities in China, and further analyzed the driving relation of the configuration of buildings such as the size, shape, and spatial distribution on k.

Tunable Berreman mode in highly conductive organic thin films.

The unique performances of Epsilon-near-zero (ENZ) materials allow them to play a crucial role in many optoelectronic devices and have spawned a wide range of inventive uses. In this paper, we found that the modified PEDOT:PSS film formed with a kind of so-called "Metastable liquid-liquid Contact (MLLC)" solution treatment method can achieve a wide tuning of ENZ wavelength from 1270 nm to 1550 nm in the near-infrared region. We further analyzed the variation trend of imaginary permittivity for these samples with different ENZ wavelengths.

A new method of hotspot analysis on the management of CO and air pollutants, a case study in Guangzhou city, China.

Emission inventory plays an important role in designing effective emission control strategies. Currently, there is unbalanced development of CO and air pollutant emission inventories in China and the spatial information of both cannot be obtained simultaneously, which prevents a collaborative control strategy. In this study, we developed a unified emission inventory including both CO and air pollutants, then utilized spatial mapping methods to identify the co-hotspots of both CO and air pollutants at a high spatial resolution (1 × 1 km).

A one-pot electrochemical synthesis of 2-aminothiazoles from active methylene ketones and thioureas mediated by NHI.

The electrochemical preparation of 2-aminothiazoles has been achieved by the reaction of active methylene ketones with thioureas assisted by ᴅʟ-alanine using NHI as a redox mediator. The electrochemical protocol proceeds in an undivided cell equipped with graphite plate electrodes under constant current conditions. Various active methylene ketones, including β-keto ester, β-keto amide, β-keto nitrile, β-keto sulfone and 1,3-diketones, can be converted to the corresponding 2-aminothiazoles.

Correlation of CT-derived pectoralis muscle status and COVID-19 induced lung injury in elderly patients.

Objectives: To explore the association between CT-derived pectoralis muscle index (PMI) and COVID-19 induced lung injury.

Methods: We enrolled 116 elderly COVID-19 patients linked to the COVID-19 outbreak in Nanjing Lukou international airport. We extracted three sessions of their CT data, including one upon admission (T1), one during the first 2 weeks when lung injury peaked (T2) and one on day 14 ± 2 (T3).

Simultaneous Monitoring of the Adenosine Triphosphate Levels in the Cytoplasm and Nucleus of a Single Cell with a Single Nanowire-Based Fluorescent Biosensor.

Simultaneous monitoring of the ATP levels at various sites of a single cell is crucial for revealing the ATP-related processes and diseases. In this work, we rationally fabricated single nanowire-based fluorescence biosensors, by which the ATP levels of the cytoplasm and nucleus in a single cell can be simultaneously monitored with a high spatial resolution. Utilizing the as-fabricated single nanowire biosensor, we demonstrated that the ATP levels of the cytoplasm were around 20-30% lower than that of the nucleus in both L929 and HeLa cells.

A perception of the nexus "resistance, recovery, resilience" of vegetations responded to extreme precipitation pulses in arid and semi-arid regions: A case study of the Qilian Mountains Nature Reserve, China.

Unprecedented pulses of extreme precipitation due to climate change are causing significant stresses and impacts on regional and even global ecosystems. However, the relationship of vegetation response to this disturbance is unclear, such as phase characteristics, extent, timing, and degree. We summarize the nexus between vegetation resistance, recovery, and resilience under three stages of extreme precipitation pulses: duration, lagging, and post-disturbance, and then construct a pragmatic scheme to quantify and validate this complex relationship based on precipitation and Normalized Difference Vegetation Index (NDVI) data for the Qilian Mountains Nature Reserve (QMNR) from 2000 to 2020.

Recent advances in photocatalytic nitrogen fixation: from active sites to ammonia quantification methods.

Photocatalytic nitrogen fixation has become a hot topic in recent years due to its mild and sustainable advantages. While modifying the photocatalyst to enhance its electron separation, light absorption and nitrogen reduction abilities, the role of the active sites in the catalytic reaction cannot be ignored because the N[triple bond, length as m-dash]N nitrogen bond is too strong to activate. This review summarizes the recent research on nitrogen fixation, focusing on the active sites for N on the catalyst surface, classifying common active sites, explaining the main role and additional role of the active sites in catalytic reactions, and discussing the methods to increase the number of active sites and their activation ability.

A Facile Preparation of Multicolor Carbon Dots.

Carbon dots (CDs) have raised broad interest because of their great potential in the fluorescence related fields, such as photocatalysis and bioimaging. CDs exhibit different optical properties when dissolved in various solvents. However, the effects of solvents during the process of preparation on the fluorescence emission of CDs are still unclear.

Sensitive and Stable Thermometer Based on the Long Fluorescence Lifetime of Au Nanoclusters for Mitochondria.

Detecting the temperature of intracellular mitochondria with high sensitivity and stability is crucial to understanding the cellular metabolism and revealing the processes of mitochondria-related physiology. In this paper, employing the long fluorescence lifetime of modified Au nanoclusters (mAuNCs) by 4-(carboxybutyl) triphenylphosphonium bromide, we developed a fluorescence lifetime thermometer with high sensitivity and stability for the temperature of the intracellular mitochondria. A high relative temperature sensitivity of 2.

Effect of 405-nm light-emitting diode on environmental tolerance of Cronobacter sakazakii in powdered infant formula.

Cronobacter sakazakii is an opportunistic pathogen that can survive extreme desiccation, heat, acid, and osmotic stress. This can increase the risk of infection, resulting in severe diseases, mainly in neonates. The inactivation effect of 405 ± 5-nm light-emitting diode (LED) illumination on C.

Convenient Preparation of -Acylbenzoxazines from Phenols, Nitriles, and DMSO Initiated by a Catalytic Amount of (COCl).

A convenient preparation method of -acylbenzoxazines has been developed, in which phenols react with nitriles and dimethyl sulfoxide (DMSO) in the presence of a catalytic amount of (COCl) in CHCN or chloroform to afford the corresponding -acylbenzoxazines in moderate-to-good yields. DMSO acts as a source of HCHO, which is generated in situ from the decomposition of a methoxydimethylsulfonium salt. A regeneration cycle of the methoxydimethylsulfonium salt is proposed, which is initiated by a catalytic amount of (COCl).

TGF-β/Alk5 signaling prevents osteoarthritis initiation via regulating the senescence of articular cartilage stem cells.

Osteoarthritis (OA) is the most common joint disease. The surface of joint cartilage is a defensive and first affected structure of articular cartilage (AC) during the pathogenesis of OA. Alk5 signaling is critical for maintaining AC homeostasis, however, the role and underlying mechanism for the involvement of Alk5 signaling in the phenotypes of articular cartilage stem cells (ACSCs) at the surface of AC is still unclear.

The relationship between intracranial arterial dolichoectasia and intracranial atherosclerosis.

Objective: We aimed to investigate the relationship between intracranial arterial dolichoectasia (IADE) and intracranial atherosclerosis (ICAS).

Methods: Patients with acute ischemic stroke were screened via the Nanjing Stroke Registry Program. Patients were diagnosed with IADE (diameter, height of bifurcation, and laterality of basilar artery) based on magnetic resonance imaging (MRI)/magnetic resonance angiography (MRA) results.