Ultrasmall copper nanoclusters have recently emerged as promising photocatalysts for organic synthesis, owing to their exceptional light absorption ability and large surface areas for efficient interactions with substrates. Despite significant advances in cluster-based visible-light photocatalysis, the types of organic transformations that copper nanoclusters can catalyze remain limited to date. Herein, we report a structurally well-defined anionic Cu nanocluster that emits in the second near-infrared region (NIR-II, 1000-1700 nm) after photoexcitation and can conduct single-electron transfer with fluoroalkyl iodides without the need for external ligand activation.
View Article and Find Full Text PDFTo investigate the prognostic value of lymph node status in patients with cervical cancer (CC) patients who underwent neoadjuvant chemotherapy (NACT) and followed hysterectomy. Patients in two referral centers were retrospectively analyzed. The baseline tumor size and radiological lymph node status (LNr) were evaluated on pre-NACT MRI.
View Article and Find Full Text PDFTwo unprecedented tetratriacontanuclear and tetraicosanuclear gold(I) sulfido clusters (denoted as and ) with different temperature-induced stimulus-responsive behavior and emission property have been constructed by taking advantage of the judiciously designed bidentate phosphine ligand. represents the highest nuclearity of the gold(I) sulfido cluster with more than a thousand atoms in the molecule. Octagonal macrocycles based on metal-cluster nodes have been assembled for the first time.
View Article and Find Full Text PDFPurpose: To investigate the potential of intravoxel incoherent motion diffusion-weighted imaging (IVIM) for preoperative prediction of lymphovascular invasion (LVI) in gastric cancer (GC).
Methods: This study prospectively enrolled 90 patients (62 males, 28 females, 60.79 ± 9.
Stimuli-responsive structural transformation has attracted much attention for its potential to mimic the behavior of biological transformations and functions. Here, two unprecedented dodecanuclear and pentadecanuclear gold(I) sulfido clusters (denoted and , respectively) with impressive stimuli-responsive interconversion have been obtained by taking advantage of the judiciously designed tridentate phosphine ligand L as the building block. Both UV light and temperature can be applied to trigger the structural conversions between and .
View Article and Find Full Text PDFDecanuclear and pentanuclear gold(I) sulfido complexes of phenanthrene- and dibenzothiophene-based diphosphine ligands were synthesized and characterized. Unprecedented stimuli-induced reversible transformation between decanuclear and pentanuclear gold(I) sulfido complexes was observed, which could be readily monitored by NMR and UV-vis absorption spectroscopy in solution. Remarkably, the decanuclear gold(I) sulfido complex () was found to show a highly reversible transformation process, which is stable for over 10 successive cycles in solution.
View Article and Find Full Text PDFPurpose: To investigate the efficacy of diffusion-weighted imaging (DWI) and dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) for the early prediction of the pathologic response to neoadjuvant chemotherapy (NAC) in patients with locally advanced gastric cancer (LAGC).
Methods: Fifty patients with LAGC who were treated with NAC followed by radical gastrectomy were enrolled. Uncontrasted and DCE-MRI were performed within 1 week before NAC.
Background: Sexual dysfunction after cardiac surgery can seriously affect patients' quality of life, but the impact of cardiac surgery on sexual function has long been neglected. Compared with conventional cardiac surgery, minimally invasive cardiac surgery has the advantages of aesthetic appearance and no disruption of the sternal structure, which can greatly improve the patient's quality of life. However, studies focusing on the effects of minimally invasive mitral valve surgery (MIMVS) on sexual function have not been reported.
View Article and Find Full Text PDFSelf-assembly of three-dimensional (3D) metallosupramolecular cages has drawn increasing attention for their potential to interconvert between different architectures due to the dynamic and reversible features of the coordination bond. These supramolecular transformations can provide unique approaches for the construction of stimuli-responsive supramolecular model systems to mimic biological transformation processes. While gold(I) clusters have attracted much interest due to their propensity to exhibit aurophilic interactions, the construction of 3D gold(I) cluster cages has remained a challenging and daunting task.
View Article and Find Full Text PDFObjective: To compare the effects of modified triple-branched stent implantation and frozen elephant trunk technique on the quality of life (QoL) of acute Stanford Type A aortic dissection (AAAD) patients at different follow-up times.
Methods: Data from 175 AAAD survivors was collected which were divided into two groups according to different surgical techniques: (group A): modified triple-branched stent graft implantation; (group B): frozen elephant trunk. The SF-36 were used to assess the QoL at discharge (AD), the third postoperative month (POM3), and the twelfth postoperative month (POM12).
Background: Hepatocellular carcinoma (HCC) includes cryptogenic hepatocellular carcinomas (CR-HCC) that lack a defined cause. Specific DNA methylation patterns and comparisons of the aberrant alterations in DNA methylation between CR-HCC and adjacent peritumor tissues (APTs) have not yet been reported.
Methods: The SureSelectXT Methyl-Seq Target Enrichment System was used to sequence targeted DNA methylation in three paired CR-HCC tissues and APTs.
Background: The patch neointima technique is a modified valve-sparing aortic root repair surgery for acute type A aortic dissection and the short-term outcomes are satisfactory. The midterm outcomes have not been reported.
Methods: From January 2009 to December 2012, 147 patients underwent valve-sparing aortic root repair with the patch neointima technique for type A aortic dissection in our center.
Background: We studied early poor postoperative prognosis in acute Stanford type A aortic dissection (ATAAD) patients and investigated the predictive effect of interleukin-6 (IL-6) combined with D-dimer in the early poor postoperative prognosis after ATAAD.
Methods: Data on 141 ATAAD patients, who underwent emergency surgery between January 2018 and December 2018 at our hospital, were studied. We analyzed early postoperative prognosis using two patient groups.
A series of polynuclear gold(I) sulfido complexes of bis(diphenylphosphino)amine ligands has been synthesized and characterized. A rather small variation in the conformation of the bis(diphenylphosphino)amine ligands has led to distinct differences in the identity of the polynuclear gold(I) sulfido complexes formed. Unprecedented concentration-dependent and solvation-dependent reversible cluster-to-cluster transformation between a dodecanuclear gold(I) sulfido complex () and a hexanuclear gold(I) sulfido complex () has been observed.
View Article and Find Full Text PDFBackground: The efficacy of hemiarch replacement combined with a modified triple-branched stent graft in Debakey type I aortic dissection remains to be confirmed.
Methods: From January 2016 to December 2017, 167 patients with acute Debakey type I aortic dissection underwent hemiarch replacement combined with a modified triple-branched stent graft. The clinical and imaging data were retrospectively analyzed.
Stereocontrolled self-assembly of a dinuclear triple-stranded europium helicate (Eu2L3) based on DTE-functionalized ligands has been achieved via the chiral-induction strategy. The point-chirality of the ligands is transferred to give either Δ or Λ metal-centers and hence leads to the overall P or M helical senses. CD spectroscopy and NMR enantiomeric differentiation experiments have confirmed the formation of enantiomers.
View Article and Find Full Text PDFMultivalent cooperativity plays an important role in the supramolecular self-assembly process. Herein, we report a remarkable cooperative enhancement of both structural integrity and metal ion selectivity on metal-organic ML tetrahedral cages self-assembled from a tris-tridentate ligand (L) with a variety of metal ions spanning across the periodic table, including alkaline earth (Ca), transition (Cd), and all the lanthanide (Ln) metal ions. All these ML cages are stable to excess metal ions and ligands, which is in sharp contrast with the tridentate (L) ligand and bis-tridentate (L) ligand bearing the same coordination motif as L.
View Article and Find Full Text PDFLanthanide-containing molecules have many potential applications in material science and biology, that is, luminescent sensing/labling, MRI, magnetic refrigeration, and catalysis among others. Coordination-directed self-assembly has shown great power in the designed construction of well-defined supramolecular systems. However, application of this strategy to the lanthanide edifices is challenging due to the complicated and greatly labile coordination numbers and geometries for lanthanides.
View Article and Find Full Text PDFCoordination-directed self-assembly has become a well-established technique for the construction of functional supramolecular structures. In contrast to the most often exploited transition metals, trivalent lanthanides Ln(III) have been less utilized in the design of polynuclear self-assembled structures despite the wealth of stimulating applications of these elements. In particular, stereochemical control in the assembly of lanthanide chiral cage compounds is not easy to achieve in view of the usually large lability of the Ln(III) ions.
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