The Co-Inoculation Effect on Growth with Synthetic Microbial Communities (SynComs) and Their Potential in Agrobiotechnology.

The use of rhizospheric SynComs can be a new and sustainable strategy in the agrobiotechnology sector. The objective of this study was to create the most appropriate SynCom composition; examine the ability to dissolve natural rock phosphate (RP) from Morocco in liquid-modified NBRIP medium; determine organic acids, and phytohormones; and verify plant growth promoting and nutrition uptake effect in the pot experiments of winter wheat (). A total of nine different microorganisms were isolated, which belonged to three different genera: , , and .

Phosphate Solubilizing Microorganism sp. MVY-004 and Its Significance for Biomineral Fertilizers' Development in Agrobiotechnology.

In this study, a phosphate solubilizing microorganism was isolated from the soil of an agricultural field in Lithuania. Based on 16S rRNA gene sequence analysis, the strain was identified as sp. and submitted to the NCBI database, Sector of Applied Bio-catalysis, University Institute of Biotechnology, Vilnius, Lithuania and allocated the accession number KY882273.

Solvates of Dasatinib: Diversity and Isostructurality.

A series of dasatinib crystalline forms were obtained, and a hierarchical cluster analysis of their powder X-ray diffraction patterns was performed. The resulting dendrogram implies 3 structural groups. The crystal structures of several solvates representing 2 of these groups were determined.

Mechanistic and Kinetic Insight into Spontaneous Cocrystallization of Isoniazid and Benzoic Acid.

Solid-state cocrystallization is of contemporary interest because it offers an easy and efficient way to produce cocrystals, which are recognized as prospective pharmaceutical materials. Research explaining solid-state cocrystallization mechanisms is important but still too scarce to give a broad understanding of factors governing and limiting these reactions. Here we report an investigation of the mechanism and kinetics of isoniazid cocrystallization with benzoic acid.

Protonation effects on the UV/Vis absorption spectra of imatinib: a theoretical and experimental study.

An experimental and theoretical investigation of protonation effects on the UV/Vis absorption spectra of imatinib showed systematic changes of absorption depending on the pH, and a new absorption band appeared below pH 2. These changes in the UV/Vis absorption spectra were interpreted using quantum chemical calculations. The geometry of various imatinib cations in the gas phase and in ethanol solution was optimized with the DFT/B3LYP method.

Cinnamic acid hydrogen bonds to isoniazid and N'-(propan-2-ylidene)isonicotinohydrazide, an in situ reaction product of isoniazid and acetone.

A new polymorph of the cinnamic acid-isoniazid cocrystal has been prepared by slow evaporation, namely cinnamic acid-pyridine-4-carbohydrazide (1/1), C9H8O2·C6H7N3O. The crystal structure is characterized by a hydrogen-bonded tetrameric arrangement of two molecules of isoniazid and two of cinnamic acid. Possible modification of the hydrogen bonding was investigated by changing the hydrazide group of isoniazid via an in situ reaction with acetone and cocrystallization with cinnamic acid.

The effect of pH on polymorph formation of the pharmaceutically active compound tianeptine.

The anti-depressant pharmaceutical tianeptine has been investigated to determine the dynamics of polymorph formation under various pH conditions. By varying the pH two crystalline polymorphs were isolated. The molecular and crystal structures have been determined to identify the two polymorphs.

Bis(N,N'-diphenyl-benzamidinium) fumarate.

The crystal structure of the title compound, 2C(19)H(17)N(2) (+)·C(4)H(2)O(4) (2-), consists of centrosymmetric trimers built up of two crystallographically independent N,N'-diphenyl-benzamid-in-ium cations and one fumarate dianion, which is located on a centre of inversion. The components of the trimers are linked by N-H⋯O hydrogen bonding. In the cation, the outer rings make dihedral angles of 53.

Dipotassium 4,4'-(hexane-3,4-di-yl)bis-(benzene-sulfonate) dihydrate.

The anion of the title compound, also called sygethin dihydrate, 2K(+)·C(18)H(20)O(6)S(2) (2-)·2H(2)O, has crystallographic inversion symmetry. The K(+) cation is surrounded by eight O atoms in a distorted cubic coordination geometry, forming extended K-O-S networks. There are also O-H⋯O hydrogen bonds.

N-(2,6-Dimethyl-anilino)-5,6-dihydro-4H-1,3-thia-zin-3-ium chloride monohydrate.

In the title compound, alternatively called xylazine hydro-chloride monohydrate, C(12)H(17)N(2)S(+)·Cl(-)·H(2)O, the six-membered thia-zine ring is in a half-chair conformation. In the crystal structure, six component centrosymmetric clusters are formed via inter-molecular O-H⋯Cl, N-H⋯O and N-H⋯Cl hydrogen bonds involving xylazine cations, chloride anions and water mol-ecules.